Page last updated: 2024-08-23

perfosfamide and Pregnancy

perfosfamide has been researched along with Pregnancy in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's4 (26.67)18.2507
2000's6 (40.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hales, BF; Huang, C2
Hales, BF; Vinson, RK1
Cornel, L; Little, SA; Mirkes, PE; Soleman, D1
Barrier, M; Beyer, R; Kerr, MK; Little, SA; Mikheev, AM; Mikheeva, S; Mirkes, PE1
Jacob-Müller, U; Spielmann, H1
Cornel, L; Doggett, B; Mirkes, PE1
Hales, BF; Moallem, SA1
Adel Moallem, S; Hales, BF1
Little, SA; Mirkes, PE3
Cornel, LM; Mirkes, PE; Wilson, KL1
Hales, BF; Jain, R1
Hales, BF; Slott, VL1

Other Studies

15 other study(ies) available for perfosfamide and Pregnancy

ArticleYear
Teratogen responsive signaling pathways in organogenesis stage mouse limbs.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 27, Issue:2

    Topics: Animals; Cluster Analysis; Cyclophosphamide; Female; Forelimb; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Regulatory Networks; Genes, Tumor Suppressor; Gestational Age; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Oncogenes; Organogenesis; Pregnancy; Signal Transduction; Teratogens; Time Factors; Tissue Culture Techniques; Transcription Factors; Transcriptional Activation

2009
Effects of exposure to a DNA damaging agent on the hypoxia inducible factors in organogenesis stage mouse limbs.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Animals; Apoptosis Regulatory Proteins; Cyclophosphamide; DNA; DNA Damage; DNA-Binding Proteins; Female; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Limb Buds; Mice; Organogenesis; Pregnancy; Repressor Proteins; Transcription Factors; Vascular Endothelial Growth Factor A

2012
Genotoxic stress response gene expression in the mid-organogenesis rat conceptus.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:1

    Topics: Animals; Cyclophosphamide; DNA Damage; Female; Gene Expression Regulation, Developmental; In Situ Hybridization; Mutation; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnancy; Rats; RNA, Antisense; Stress, Physiological

2003
Teratogen-induced activation of the mitochondrial apoptotic pathway in the yolk sac of day 9 mouse embryos.
    Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Caspases; Cyclophosphamide; Drug Resistance; Enzyme Activation; Female; Fetal Heart; Fetal Proteins; Gestational Age; Head; Hot Temperature; Mice; Mitochondria; Organ Culture Techniques; Organ Specificity; Pregnancy; Staurosporine; Teratogens; Yolk Sac

2003
Alterations in gene expression induced in day-9 mouse embryos exposed to hyperthermia (HS) or 4-hydroperoxycyclophosphamide (4CP): analysis using cDNA microarrays.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:2

    Topics: Animals; Cholesterol; Cyclophosphamide; Embryo, Mammalian; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, p53; Hyperthermia, Induced; Mice; Oligonucleotide Array Sequence Analysis; Pregnancy; RNA, Messenger; Teratogens

2004
Investigation on cyclophosphamide treatment during the preimplantation period. II. In vitro studies on the effects of cyclophosphamide and its metabolites 4-OH-cyclophosphamide, phosphoramide mustard, and acrolein on blastulation of four-cell and eight-ce
    Teratology, 1981, Volume: 23, Issue:1

    Topics: Acrolein; Aldehydes; Animals; Blastocyst; Cyclophosphamide; Dose-Response Relationship, Drug; Embryonic Development; Female; Mice; Phosphoramide Mustards; Pregnancy; Teratogens

1981
Induction of a heat shock response (HSP 72) in rat embryos exposed to selected chemical teratogens.
    Teratology, 1994, Volume: 49, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acetoxyacetylaminofluorene; Animals; Antibodies, Monoclonal; Arsenites; Cadmium; Cadmium Chloride; Chlorides; Cyclophosphamide; Embryonic and Fetal Development; Female; Fetal Death; Fetal Proteins; Gene Expression Regulation; Heat-Shock Proteins; Pregnancy; Rats; Rats, Sprague-Dawley; Sodium Compounds; Sodium Salicylate; Stress, Physiological; Teratogens

1994
Induction of apoptosis and cathepsin D in limbs exposed in vitro to an activated analog of cyclophosphamide.
    Teratology, 1995, Volume: 52, Issue:1

    Topics: Animals; Apoptosis; Cathepsin D; Cyclophosphamide; DNA; Embryonic and Fetal Development; Female; Forelimb; Immunohistochemistry; In Vitro Techniques; Mice; Microscopy, Immunoelectron; Phagocytosis; Pregnancy; Teratogens

1995
Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse.
    Biology of reproduction, 1996, Volume: 55, Issue:2

    Topics: Animals; Apoptosis; Clusterin; Culture Techniques; Cyclophosphamide; DNA; Extremities; Female; Glycoproteins; Immunohistochemistry; Mice; Microscopy, Confocal; Microscopy, Immunoelectron; Molecular Chaperones; Pregnancy; Teratogens; Transglutaminases

1996
Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine.
    Toxicology and applied pharmacology, 2000, Feb-01, Volume: 162, Issue:3

    Topics: Animals; Apoptosis; Caspases; Culture Techniques; Cyclophosphamide; Cytochrome c Group; DNA Fragmentation; Embryo Implantation; Embryo, Mammalian; Enzyme Activation; Female; Hyperthermia, Induced; Male; Mice; Mitochondria; Myocardium; Pregnancy; Staurosporine; Teratogens

2000
Teratogen-induced activation of ERK, JNK, and p38 MAP kinases in early postimplantation murine embryos.
    Teratology, 2000, Volume: 62, Issue:1

    Topics: Animals; Apoptosis; Culture Techniques; Cyclophosphamide; Embryo, Mammalian; Enzyme Activation; Female; Gestational Age; Hot Temperature; JNK Mitogen-Activated Protein Kinases; Kinetics; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pregnancy; Signal Transduction; Staurosporine; Teratogens; Tissue Distribution

2000
Effects of 4-hydroperoxycyclophosphamide (4-OOH-CP) and 4-hydroperoxydechlorocyclophosphamide (4-OOH-deCICP) on the cell cycle of post implantation rat embryos.
    Teratology, 1992, Volume: 45, Issue:2

    Topics: Abnormalities, Drug-Induced; Acrolein; Animals; Biotransformation; Cell Cycle; Cell Separation; Culture Techniques; Cyclophosphamide; DNA; Embryo, Mammalian; Female; Flow Cytometry; Osmolar Concentration; Phosphoramide Mustards; Pregnancy; Rats; Teratogens

1992
Differential effects of 4-hydroperoxycyclophosphamide on limb development in vitro.
    Teratology, 1986, Volume: 34, Issue:3

    Topics: Abnormalities, Drug-Induced; Alkaline Phosphatase; Animals; Creatine Kinase; Cyclophosphamide; DNA; Dose-Response Relationship, Drug; Extremities; Female; Forelimb; Gestational Age; Hindlimb; Limb Deformities, Congenital; Mice; Mice, Inbred ICR; Organ Culture Techniques; Pregnancy; Proteins; RNA

1986
Role of the 4-hydroxy intermediate in the in vitro embryotoxicity of cyclophosphamide and dechlorocyclophosphamide.
    Toxicology and applied pharmacology, 1988, Volume: 92, Issue:2

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Female; Hydroxylation; Pregnancy; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Teratogens

1988
DNA cross-linking and single-strand breaks induced by teratogenic concentrations of 4-hydroperoxycyclophosphamide and phosphoramide mustard in postimplantation rat embryos.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Animals; Cyclophosphamide; DNA Damage; DNA, Single-Stranded; Embryonic Development; Endopeptidase K; Female; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Phosphoramide Mustards; Pregnancy; Rats; Serine Endopeptidases

1987