Page last updated: 2024-08-23

perfosfamide and Leukemia

perfosfamide has been researched along with Leukemia in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199012 (48.00)18.7374
1990's9 (36.00)18.2507
2000's1 (4.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blicharski, K; Fedoročko, P; Mazur, L; Mikeš, J; Niemeyer, U; Opydo-Chanek, M; Śladowska, K1
Shibayama, Y; Sugawara, M; Takada, K; Takekuma, Y; Tazawa, Y; Usukubo, I1
Ambinder, RF; Blackford, AL; Davis-Sproul, JM; Gocke, CD; Gore, SD; Jones, RJ; Kasamon, YL; Seifter, EJ1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S1
Colvin, MO; Hess, AD; Kaizer, H; Körbling, M; Santos, GW; Tutschka, PJ1
Braine, H; Colvin, M; Kaizer, H; Korbling, M; Santos, G; Saral, R; Stuart, R; Tutschka, P1
Douay, L; Giarratana, MC; Gorin, NC; Hu, C1
Ball, ED; Malley, V; Rubin, J1
Rosenfeld, CS1
Jones, RJ1
Clarkson, BD; Gulati, SC; Haley, JD; Lemoli, RM; Strife, A1
Jollow, DJ; Peters, RH; Stuart, RK1
Kaizer, H; Rowley, SD; Santos, GW; Yeager, AM1
Peters, RH; Stuart, RK1
Moreb, J; Rueth, S; Zucali, JR1
Colvin, OM; Santos, GW1
Konno, T; Minegishi, M; Minegishi, N; Tsuchiya, S1
Gorin, NC1
Flesch, M; Hervé, P1
Andersson, BS; Beran, M; Farquhar, D; McCredie, KB; Wang, Y1
Braine, HG; Colvin, OM; Davis, J; Jones, RJ; Rowley, SD; Santos, GW; Saral, R; Sensenbrenner, LL; Yeager, A; Zuehlsdorf, M1
Debusscher, L; Delforge, A; Loos, M; Rongé-Collard, E; Socquet, M; Stryckmans, P1
Beschorner, WE; Braine, HG; Brookmeyer, R; Burns, WH; Fuller, DJ; Kaizer, H; Korbling, M; Mangan, KF; Saral, R; Stuart, RK1
Douay, L1
Goldman, JM; Gordon, MY; Gordon-Smith, EC1

Reviews

3 review(s) available for perfosfamide and Leukemia

ArticleYear
Purging with 4-hydroperoxycyclophosphamide.
    Journal of hematotherapy, 1992,Winter, Volume: 1, Issue:4

    Topics: Acute Disease; Bone Marrow Purging; Bone Marrow Transplantation; Clinical Trials as Topic; Cyclophosphamide; Humans; Leukemia; Lymphoma

1992
Ex vivo chemopurging of autologous bone marrow with 4-hydroperoxycyclophosphamide to eliminate occult leukemic cells. Laboratory and clinical observations.
    The American journal of pediatric hematology/oncology, 1990,Fall, Volume: 12, Issue:3

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Busulfan; Child; Cyclophosphamide; Humans; Leukemia; Neoplastic Stem Cells; Remission Induction; Transplantation, Autologous; Whole-Body Irradiation

1990
Pharmacological purging of bone marrow with reference to autografting.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic

1986

Trials

3 trial(s) available for perfosfamide and Leukemia

ArticleYear
Extended follow-up of autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide (4-HC) purging for indolent or transformed non-Hodgkin lymphomas.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011, Volume: 17, Issue:3

    Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Cyclophosphamide; Female; Follow-Up Studies; Humans; Leukemia; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Survival Analysis; Transplantation Conditioning; Transplantation, Autologous

2011
Pharmacological purging of bone marrow with reference to autografting.
    Clinics in haematology, 1986, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic

1986
Autologous bone marrow transplantation in acute leukemia: a phase I study of in vitro treatment of marrow with 4-hydroperoxycyclophosphamide to purge tumor cells.
    Blood, 1985, Volume: 65, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; In Vitro Techniques; Leukemia; Leukopenia; Male; Middle Aged; Postoperative Complications; Transplantation, Autologous

1985

Other Studies

20 other study(ies) available for perfosfamide and Leukemia

ArticleYear
Comparison of
    Anticancer research, 2017, Volume: 37, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Membrane; Cell Survival; Cyclophosphamide; Esterases; Gene Expression Regulation, Neoplastic; Humans; Ifosfamide; Leukemia; Membrane Potential, Mitochondrial

2017
Schedule-dependent cytotoxicity of Etoposide and cyclophosphamide in P-glycoprotein-expressing human leukemic K-562 cells.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Cycle; Cell Survival; Cyclophosphamide; Drug Administration Schedule; Etoposide; Humans; K562 Cells; Leukemia

2014
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines.
    Investigational new drugs, 2007, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors

2007
4-hydroperoxycyclophosphamide: a model for eliminating residual human tumour cells and T-lymphocytes from the bone marrow graft.
    British journal of haematology, 1982, Volume: 52, Issue:1

    Topics: Bone Marrow Transplantation; Cells, Cultured; Cyclophosphamide; Hematopoietic Stem Cells; Humans; Leukemia; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; T-Lymphocytes; Transplantation, Autologous

1982
Autologous bone marrow transplantation in acute leukemia and non-Hodgkin's lymphoma: a phase I study of 4-hydroperoxycyclophosphamide (4HC) incubation of marrow prior to cryopreservation.
    Haematology and blood transfusion, 1983, Volume: 28

    Topics: Acute Disease; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; Drug Evaluation; Freezing; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Tissue Preservation

1983
Amifostine (WR-2721) protects normal haematopoietic stem cells against cyclophosphamide derivatives' toxicity without compromising their antileukaemic effects.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A Suppl 1

    Topics: Amifostine; Antineoplastic Agents; Bone Marrow Purging; Bone Marrow Transplantation; Cyclophosphamide; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leukemia; Neoplastic Stem Cells

1995
A combination of anti-CD15 monoclonal antibody PM-81 and 4-hydroperoxycyclophosphamide augments tumor cytotoxicity while sparing normal progenitor cells.
    Journal of hematotherapy, 1994,Summer, Volume: 3, Issue:2

    Topics: Acute Disease; Antibodies, Monoclonal; Bone Marrow Purging; Combined Modality Therapy; Cyclophosphamide; Cytotoxicity, Immunologic; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid; Leukocytes, Mononuclear; Lewis X Antigen; Tumor Cells, Cultured

1994
Antileukemic activity of phenylalanine methyl ester (PME): a lysosomotropic peptide methyl ester.
    Stem cells (Dayton, Ohio), 1994, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blast Crisis; Child; Cyclophosphamide; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Monocytes; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Temperature; Tumor Cells, Cultured

1994
TGF-beta 3 protects normal human hematopoietic progenitor cells treated with 4-hydroperoxycyclophosphamide in vitro.
    Experimental hematology, 1992, Volume: 20, Issue:11

    Topics: Bone Marrow Cells; Bone Marrow Purging; Cell Survival; Cyclophosphamide; Erythroid Precursor Cells; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Lymphoma; Macrophages; Transforming Growth Factor beta; Tumor Cells, Cultured

1992
Role of glutathione in the in vitro synergism between 4-hydroperoxy-cyclophosphamide and cisplatin in leukemia cell lines.
    Cancer research, 1991, May-15, Volume: 51, Issue:10

    Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Drug Screening Assays, Antitumor; Drug Synergism; Glutathione; Humans; Kinetics; Leukemia; Leukemia, Experimental; Methionine Sulfoximine

1991
Synergism between 4-hydroperoxycyclophosphamide and cisplatin: importance of incubation sequence and measurement of cisplatin accumulation.
    Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3

    Topics: Cell Survival; Cisplatin; Cyclophosphamide; Drug Synergism; Humans; Leukemia; Platinum; Spectrophotometry, Atomic; Tumor Cells, Cultured

1990
The effects of tumor necrosis factor-alpha on early human hematopoietic progenitor cells treated with 4-hydroperoxycyclophosphamide.
    Blood, 1990, Aug-15, Volume: 76, Issue:4

    Topics: Cell Line; Cyclophosphamide; Hematopoietic Stem Cells; Humans; Interleukin-1; Leukemia; Tumor Necrosis Factor-alpha

1990
Effects of in vitro treatment with 4-hydroperoxycyclophosphamide and hyperthermia on leukemic progenitor cells.
    The Tohoku journal of experimental medicine, 1989, Volume: 159, Issue:2

    Topics: Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Female; Fever; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Infant; Leukemia; Male; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Autologous bone marrow transplantation in acute leukemia.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Acute Disease; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Bone Marrow Transplantation; Cyclophosphamide; Hematopoietic Stem Cells; Humans; Leukemia; Magnetics; Neprilysin; Rabbits; Recurrence; Ricin; Transplantation, Autologous; Whole-Body Irradiation

1986
[Cellular sorting methods in autologous (elimination of residual malignant cells) or allogeneic (T lymphocyte elimination) bone marrow grafts. Clinical pilot studies].
    Nouvelle revue francaise d'hematologie, 1986, Volume: 28, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cell Separation; Centrifugation, Density Gradient; Cyclophosphamide; Graft vs Host Disease; Humans; Lectins; Leukemia; Lymphocyte Depletion; Methylprednisolone; Neoplasms; Neprilysin; Pilot Projects; Plant Lectins; Ricin; Soybean Proteins; T-Lymphocytes; Transplantation, Autologous; Transplantation, Homologous

1986
The effects of acetaldophosphamide, a novel stable aldophosphamide analogue, on normal human and leukemic progenitor cells in vitro: implications for use in bone marrow purging.
    Cancer research, 1988, Jan-15, Volume: 48, Issue:2

    Topics: Bone Marrow; Bone Marrow Transplantation; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Leukemia; Neoplastic Stem Cells; Phosphoramide Mustards; Regeneration

1988
CFU-GM content of bone marrow graft correlates with time to hematologic reconstitution following autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide-purged bone marrow.
    Blood, 1987, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Child; Child, Preschool; Colony-Forming Units Assay; Cyclophosphamide; Female; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Leukocyte Count; Macrophages; Male; Middle Aged; Platelet Count; Transplantation, Autologous

1987
Effect of 4-hydroperoxycyclophosphamide on leukemic and normal human myeloid progenitor cells.
    Leukemia research, 1985, Volume: 9, Issue:5

    Topics: Acute Disease; Bone Marrow; Cyclophosphamide; Dose-Response Relationship, Drug; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Myeloid, Acute; Tumor Stem Cell Assay

1985
Cyclophosphamide derivatives for in vitro cleansing of leukemic bone marrow.
    Revue francaise de transfusion et immuno-hematologie, 1985, Volume: 28, Issue:5

    Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Burkitt Lymphoma; Cell Line; Cell Separation; Cyclophosphamide; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Experimental; Mice; Rats

1985
4-Hydroperoxycyclophosphamide inhibits proliferation by human granulocyte-macrophage colony-forming cells (GM-CFC) but spares more primitive progenitor cells.
    Leukemia research, 1985, Volume: 9, Issue:8

    Topics: Anemia, Aplastic; Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Drug Resistance; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Macrophages; Transplantation, Autologous

1985