Page last updated: 2024-08-23

perfosfamide and Breast Neoplasms

perfosfamide has been researched along with Breast Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's20 (74.07)18.2507
2000's3 (11.11)29.6817
2010's0 (0.00)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Dziegiel, P; Jablonska, K; Maciejczyk, A; Matkowski, R; Partynska, A; Suchanski, J; Szymczak-Kulus, K; Ugorski, M; Urbaniak, A1
Bocci, G; Kerbel, RS; Nicolaou, KC1
Blomqvist, C; Larsson, R; Nygren, P; Villman, K1
Braine, HG; Clarke, B; Davidson, NE; Davis, JM; Huelskamp, AM; Noga, SJ; Ohly, K; Passos-Coelho, JL; Schepers, KG; Wright, SK1
Crown, JP; Kritz, A; Moore, MA; Norton, L; Reich, L; Schneider, JG; Wasserheit, C; Wong, G1
Bearman, SI; Jones, RB; Myers, S; Purdy, M; Shpall, EJ; Stemmer, SM1
Davidson, NE; Davis, J; Huelskamp, AM; Kennedy, MJ; Noga, SJ; Ohly, K; Passos-Coelho, J1
Colvin, OM; Gamcsik, MP; Millis, KK1
Gurtler, J; Liebmann, J1
Chen, G; Waxman, DJ1
Davis, JM; Eby, LL; Noga, SJ; Schepers, KG1
Graham, CH; Kapitain, SJ; Kerbel, RS; Kobayashi, H; Man, S; Stankiewicz, KS1
Kuroi, K; Sato, Y; Toge, T; Yamaguchi, Y1
Clarke, B; Davidson, NE; Davis, JM; Huelskamp, AM; Kennedy, MJ; Noga, SJ; Passos-Coelho, J; Ross, AA1
Bast, RC; Bearman, SI; Bonner, HS; Franklin, WA; Hami, L; McCulloch, W; Peters, WP; Shaw, L; Shpall, EJ; Stemmer, SM1
Sladek, NE; Sreerama, L1
Bearman, SI; Cagnoni, PJ; Capizzi, R; Franklin, WA; Hami, L; Jones, RB; Ross, M; Schein, PS; Shpall, EJ1
Ericson, SG; Fortney, J; Gibson, LF; Landreth, KS; Lynch, JP; Magro, G1
Adams, DJ; Boal, JH; Colvin, OM; Flowers, JL; Gamcsik, MP; Ludeman, SM; Shao, KL; Springer, JB1
Bast, RC; Houston, LL; O'Briant, KC; Peters, WP; Shpall, EJ1
Affronti, ML; Bast, RC; Eggleston, S; Johnston, C; Jones, RB; Rosner, GL; Ross, M; Shpall, EJ; Tepperburg, M; Vandermark, R1
Antman, KH; Eder, JP; Frei, E; Herman, TS; Holden, SA; Teicher, BA1
Anderson, IC; Bast, RC; Edwards, S; Eggleston, S; Johnston, C; Joines, WT; Jones, RB; Ross, M; Shpall, EJ; Tepperberg, M1
Hug, V; Johnston, D; Polyzos, A; Thames, HD1
Finders, M; Hortobagyi, G; Hug, V; Thames, H1
Daidone, MG; De Lena, M; Sanfilippo, O; Silvestrini, R; Varini, M; Zaffaroni, N1

Trials

6 trial(s) available for perfosfamide and Breast Neoplasms

ArticleYear
Predictive factors for peripheral-blood progenitor-cell collections using a single large-volume leukapheresis after cyclophosphamide and granulocyte-macrophage colony-stimulating factor mobilization.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:3

    Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Breast Neoplasms; Cyclophosphamide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukocyte Count; Middle Aged; Platelet Count; Predictive Value of Tests; Thiotepa

1995
Factors affecting the mobilization of primitive and committed hematopoietic progenitors into the peripheral blood of cancer patients.
    Bone marrow transplantation, 1994, Volume: 14, Issue:6

    Topics: Adult; Antigens, CD; Antigens, CD34; Blood Cells; Bone Marrow Cells; Bone Marrow Transplantation; Breast Neoplasms; Cell Separation; Combined Modality Therapy; Cyclophosphamide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Interleukin-1; Middle Aged; Ovarian Neoplasms; Stem Cell Factor

1994
New strategies in marrow purging for breast cancer patients receiving high-dose chemotherapy with autologous bone marrow transplantation.
    Breast cancer research and treatment, 1993, Volume: 26 Suppl

    Topics: Amifostine; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Stem Cells

1993
Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support.
    Blood, 1994, Jun-01, Volume: 83, Issue:11

    Topics: Adult; Amifostine; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Hematopoietic Stem Cells; Humans; Transplantation, Autologous

1994
Use of amifostine in bone marrow purging.
    Seminars in oncology, 1996, Volume: 23, Issue:4 Suppl 8

    Topics: Adult; Amifostine; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Hematopoietic Stem Cells; Hodgkin Disease; Humans; Lymphoma, Non-Hodgkin; Middle Aged; Premedication; Treatment Outcome

1996
4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support: a phase I trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplastic Stem Cells; Survival Rate

1991

Other Studies

21 other study(ies) available for perfosfamide and Breast Neoplasms

ArticleYear
Prolactin-induced protein (PIP) increases the sensitivity of breast cancer cells to drug-induced apoptosis.
    Scientific reports, 2023, 04-21, Volume: 13, Issue:1

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Female; Glycoproteins; Humans; Membrane Transport Proteins; Mice; Paclitaxel; Prolactin

2023
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.
    Cancer research, 2002, Dec-01, Volume: 62, Issue:23

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Bridged-Ring Compounds; Cell Division; Cell Survival; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Endothelium, Vascular; Epothilones; Humans; Paclitaxel; Tumor Cells, Cultured

2002
Predictive value of in vitro assessment of cytotoxic drug activity in advanced breast cancer.
    Anti-cancer drugs, 2005, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Survival; Cyclophosphamide; Disease Progression; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Female; Fluorometry; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Predictive Value of Tests; Prospective Studies; Quality Control; Retrospective Studies; Taxoids; Treatment Outcome; Tumor Cells, Cultured

2005
Administration of human recombinant granulocyte colony-stimulating factor (filgrastim) accelerates granulocyte recovery following high-dose chemotherapy and autologous marrow transplantation with 4-hydroperoxycyclophosphamide-purged marrow in women with m
    Cancer research, 1993, Nov-15, Volume: 53, Issue:22

    Topics: Adult; Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Length of Stay; Leukocyte Count; Middle Aged; Neutrophils; Novobiocin; Recombinant Proteins; Thiotepa

1993
Amifostine shortens bone marrow recovery period in breast cancer patients.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:1

    Topics: Amifostine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Breast Neoplasms; Cyclophosphamide; Humans; Leukocytes

1995
Noninvasive detection of elevated glutathione levels in MCF-7 cells resistant to 4-hydroperoxycyclophosphamide.
    Cancer research, 1995, May-15, Volume: 55, Issue:10

    Topics: Breast Neoplasms; Cell Division; Cyclophosphamide; Drug Resistance; Glutathione; Humans; Magnetic Resonance Spectroscopy; Tumor Cells, Cultured

1995
Combination intraventricular therapy with thiotepa and cytarabine in meningeal carcinomatosis due to breast cancer: in vitro evidence for supra-additive cytotoxicity.
    Anti-cancer drugs, 1995, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Cytarabine; Drug Resistance; Drug Synergism; Female; Humans; Injections, Intraventricular; Meningeal Neoplasms; Middle Aged; Salvage Therapy; Thiotepa; Tumor Cells, Cultured

1995
Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells.
    Biochemical pharmacology, 1995, May-26, Volume: 49, Issue:11

    Topics: Aldehyde Dehydrogenase; Aldehydes; Breast Neoplasms; Buthionine Sulfoximine; Cell Line; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Ethacrynic Acid; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Humans; Methionine Sulfoximine

1995
Comparison of progenitor cell concentration techniques: continuous flow separation versus density-gradient isolation.
    Journal of hematotherapy, 1993,Fall, Volume: 2, Issue:3

    Topics: Adult; Bone Marrow Cells; Bone Marrow Purging; Breast Neoplasms; Cell Count; Cell Separation; Centrifugation, Density Gradient; Child; Cyclophosphamide; Erythrocyte Count; Hematocrit; Hematopoietic Stem Cells; Humans; Indicators and Reagents; Neoplasms; United States; United States Food and Drug Administration

1993
Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents.
    Journal of the National Cancer Institute, 1994, Jul-06, Volume: 86, Issue:13

    Topics: Animals; Breast Neoplasms; Cisplatin; Cyclophosphamide; Drug Resistance; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Time Factors; Tumor Cells, Cultured

1994
Modulation of suppressor cell activities by cyclophosphamide in breast cancer patients.
    Journal of clinical laboratory analysis, 1994, Volume: 8, Issue:3

    Topics: Breast Neoplasms; Concanavalin A; Cyclophosphamide; Female; Humans; T-Lymphocytes, Regulatory

1994
Bone marrow micrometastases in chemotherapy-responsive advanced breast cancer: effect of ex vivo purging with 4-hydroperoxycyclophosphamide.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: Adult; Bone Marrow; Bone Marrow Purging; Breast Neoplasms; Cyclophosphamide; Female; Humans; Middle Aged; Prospective Studies; Tumor Stem Cell Assay

1994
Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
    Biochemical pharmacology, 1993, Jun-22, Volume: 45, Issue:12

    Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Benzaldehydes; Breast Neoplasms; Cell Line; Cyclophosphamide; Drug Resistance; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Humans; Hydrogen-Ion Concentration; Isoenzymes; NAD; NADP; Subcellular Fractions; Temperature

1993
Regulation of BAX and BCL-2 expression in breast cancer cells by chemotherapy.
    Breast cancer research and treatment, 1999, Volume: 55, Issue:2

    Topics: Adenocarcinoma; Annexin A5; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Estrogens; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1999
Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:4

    Topics: Acrolein; Antineoplastic Agents, Alkylating; Aziridines; Breast Neoplasms; Cell Count; Cell Nucleus; Cell Survival; Cyclophosphamide; Humans; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Tumor Cells, Cultured

2000
Elimination of clonogenic breast cancer cells from human bone marrow. A comparison of immunotoxin treatment with chemoimmunoseparation using 4-hydroperoxycyclophosphamide, monoclonal antibodies, and magnetic microspheres.
    Cancer, 1991, Sep-15, Volume: 68, Issue:6

    Topics: Antibodies, Monoclonal; Bone Marrow; Bone Marrow Examination; Bone Marrow Transplantation; Bone Neoplasms; Breast Neoplasms; Cell Separation; Clone Cells; Cyclophosphamide; Humans; Immunotoxins; In Vitro Techniques; Magnetics; Microspheres; Transplantation, Autologous; Tumor Stem Cell Assay

1991
Preclinical studies relating to the use of thiotepa in the high-dose setting alone and in combination.
    Seminars in oncology, 1990, Volume: 17, Issue:1 Suppl 3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Cell Hypoxia; Cell Survival; Cyclophosphamide; Drug Administration Schedule; Drug Combinations; Fluorocarbons; Half-Life; Humans; Hydroxyethyl Starch Derivatives; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Thiotepa; Tumor Cells, Cultured

1990
Immunopharmacologic purging of breast cancer from bone marrow for autologous bone marrow transplantation.
    Progress in clinical and biological research, 1990, Volume: 333

    Topics: Antibodies, Monoclonal; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Breast Neoplasms; Colony-Forming Units Assay; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Humans; Magnetics; Microspheres; Transplantation, Autologous; Tumor Cells, Cultured

1990
Chemoresistance is not a cause of the apparent failure of adjuvant chemotherapy in postmenopausal women.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Fluorouracil; Humans; Menopause; Middle Aged; Tumor Stem Cell Assay; Vinblastine

1988
Chemosensitivities of human clonogenic breast tumor cells.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:8

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclophosphamide; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Humans; In Vitro Techniques; Tumor Stem Cell Assay

1986
Reliability of an in vitro short-term assay to predict the drug sensitivity of human breast cancer.
    Cancer, 1985, Aug-01, Volume: 56, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colony-Forming Units Assay; Combined Modality Therapy; Cyclophosphamide; DNA, Neoplasm; Doxorubicin; Female; Humans; Mastectomy; RNA, Neoplasm; Tumor Stem Cell Assay; Vincristine

1985