perfluorooctanoic acid has been researched along with Acute Liver Injury, Drug-Induced in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 6 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, B; Lu, W; Luan, T; Tu, L; Yao, Y; Yu, T; Zhang, R | 1 |
| Chen, J; Lin, H; Liu, F; Liu, Z; Shen, L; Wu, H; Yang, H; Zhang, H; Zhang, X; Zhong, Y | 1 |
| Ikeda-Araki, A; Kojima, H; Kubota, A; Murase, W; Nakagawa, K; Shizu, R; Terasaki, M; Yoshinari, K | 1 |
| An, H; Ao, L; Cao, J; Chen, Q; Cui, H; He, S; Ling, X; Liu, J; Wang, L; Yang, W; Yang, Z; Zou, P | 1 |
| Chen, YK; Lai, MQ; Wang, Q; Xie, XL; Xu, LL; Zhang, QY; Zhong, MT | 1 |
| Arif, W; Chen, J; Irudayaraj, J; Kalsotra, A; Li, J; Wen, Y | 1 |
| Wu, W; Wu, X; Xie, G; Xu, X; Yang, B | 1 |
| Chen, B; Ding, Y; Du, Q; Gao, N; He, J; Jia, X; Jiang, J; Li, N; Liu, W; Liu, Z; Lu, X; Tang, J; Wu, Y; Zhang, H; Zhu, W | 1 |
| Ehrich, MF; Orbach, SM; Rajagopalan, P | 1 |
| Klaunig, JE; Li, X; Wang, Z | 1 |
| Dai, J; Guo, H; Guo, X; Guo, Y; Sheng, N; Sun, S; Sun, Y; Wang, J; Yao, J; Zhang, X | 1 |
| Abedi-Valugerdi, M; Depierre, JW; Hassan, M; Nelson, BD; Qazi, MR | 1 |
| Hu, Z; Kuang, H; Liu, F; Wang, J; Wei, J; Wu, L; Yang, B; Yang, S; Zhang, D; Zhou, L; Zou, T; Zou, W | 1 |
| Bitter, K; Buhrke, T; Krüger, E; Lampen, A; Pevny, S; Rößler, M | 1 |
| Liu, F; Liu, W; Wu, L; Xia, L; Yang, B; Yang, J; Zhang, D; Zou, T; Zou, W | 1 |
| Dai, J; Wang, J; Yan, S; Zhang, H; Zheng, F | 1 |
| Dai, J; Guo, X; Wang, J; Yan, S; Zhang, H | 1 |
| Dai, J; Guo, X; Guo, Y; Pan, Y; Sheng, N; Sun, Y; Zheng, F; Zhou, X | 1 |
| Anderson-Mahoney, P; Dahlgren, J; Gray, D; Kotlerman, J; Takhar, H | 1 |
| Chen, PC; Chiang, CK; Hung, KY; Lin, CY; Lin, LY; Su, YN; Wang, WJ | 1 |
| Bae, HI; Kim, SH; Shin, HI; Son, HY; Yang, JH | 1 |
21 other study(ies) available for perfluorooctanoic acid and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Metabolomics analysis of the 3D L-02 cell cultures revealing the key role of metabolism of amino acids in ameliorating hepatotoxicity of perfluorooctanoic acid.
Topics: Amino Acids; Caprylates; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Fluorocarbons; Humans; Metabolomics | 2022 |
Assessing the hepatotoxicity of PFOA, PFOS, and 6:2 Cl-PFESA in black-spotted frogs (Rana nigromaculata) and elucidating potential association with gut microbiota.
Topics: Alanine Transaminase; Alkanesulfonic Acids; Animals; Caprylates; Catalase; Chemical and Drug Induced Liver Injury; Ethers; Fluorocarbons; Gastrointestinal Microbiome; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Male; Malondialdehyde; Mitogen-Activated Protein Kinases; Molecular Docking Simulation; NF-E2-Related Factor 2; Ranidae | 2022 |
Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays.
Topics: Chemical and Drug Induced Liver Injury; HEK293 Cells; Humans; NF-E2-Related Factor 2; PPAR alpha; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcriptional Activation; Transcriptome | 2023 |
PPARα/ACOX1 as a novel target for hepatic lipid metabolism disorders induced by per- and polyfluoroalkyl substances: An integrated approach.
Topics: Alkanesulfonic Acids; Animals; Caprylates; Chemical and Drug Induced Liver Injury; Cross-Sectional Studies; Environmental Pollutants; Fluorocarbons; Humans; Lipid Metabolism; Lipid Metabolism Disorders; Mice; Non-alcoholic Fatty Liver Disease; Nutrition Surveys; PPAR alpha; Rats | 2023 |
Gestational GenX and PFOA exposures induce hepatotoxicity, metabolic pathway, and microbiome shifts in weanling mice.
Topics: Animals; Caprylates; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Fluorocarbons; Liver; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Microbiota; Pregnancy | 2024 |
Effect of PFOA on DNA Methylation and Alternative Splicing in Mouse Liver.
Topics: Alternative Splicing; Animals; Apoptosis; Caprylates; Cell Proliferation; Chemical and Drug Induced Liver Injury; DNA Methylation; DNA Methyltransferase 3A; Fatty Liver; Female; Fluorocarbons; Liver; Mice; Protein Isoforms; RNA-Binding Proteins; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Adverse bioeffect of perfluorooctanoic acid on liver metabolic function in mice.
Topics: Animals; Caprylates; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Down-Regulation; Environmental Pollutants; Fibroblast Growth Factors; Fluorocarbons; Insulin; Lipid Metabolism; Liver; Liver Function Tests; Male; Mice; Mice, Inbred Strains; Pancreas | 2018 |
Role of the Nrf2-ARE pathway in perfluorooctanoic acid (PFOA)-induced hepatotoxicity in Rana nigromaculata.
Topics: Animals; Caprylates; Chemical and Drug Induced Liver Injury; Environmental Pollutants; Fluorocarbons; Glutathione; Liver; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Protective Agents; Ranidae; Reactive Oxygen Species; Signal Transduction | 2018 |
High-throughput toxicity testing of chemicals and mixtures in organotypic multi-cellular cultures of primary human hepatic cells.
Topics: Acetaminophen; Adult; Aged; Animals; Apoptosis; Caprylates; Cell Culture Techniques; Cell Survival; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Drug Interactions; Ethanol; Female; Fluorocarbons; Glutathione; Hepatocytes; High-Throughput Screening Assays; Humans; Isoniazid; Male; Middle Aged; Rats, Inbred Lew; Toxicity Tests | 2018 |
The effects of perfluorooctanoate on high fat diet induced non-alcoholic fatty liver disease in mice.
Topics: Animals; Caprylates; Cell Proliferation; Chemical and Drug Induced Liver Injury; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Diet, High-Fat; Disease Models, Animal; Disease Progression; Environmental Pollutants; Fluorocarbons; Gene Expression Regulation; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; PPAR alpha; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Risk Assessment; Signal Transduction; Time Factors | 2019 |
Comparative Hepatotoxicity of Novel PFOA Alternatives (Perfluoropolyether Carboxylic Acids) on Male Mice.
Topics: Animals; Caprylates; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Ethers; Fluorocarbons; Liver; Male; Mice | 2019 |
Sub-acute, moderate-dose, but not short-term, low-dose dietary pre-exposure of mice to perfluorooctanoate aggravates concanavalin A-induced hepatitis.
Topics: Administration, Oral; Animals; Caprylates; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Fluorocarbons; Liver; Male; Mice; Mice, Inbred C57BL; Time Factors; Transaminases | 2013 |
Involvement of oxidative stress and inflammation in liver injury caused by perfluorooctanoic acid exposure in mice.
Topics: Animals; Caprylates; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Fluorocarbons; Hepatitis; Immunologic Factors; Male; Mice; Oxidative Stress; Reactive Oxygen Species | 2014 |
Perfluorooctanoic acid (PFOA) affects distinct molecular signalling pathways in human primary hepatocytes.
Topics: Caprylates; Cell Cycle; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cyclins; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Fluorocarbons; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Hepatocytes; Humans; Oligonucleotide Array Sequence Analysis; PPAR alpha; PPAR gamma; Primary Cell Culture; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Time Factors; Transcription Factor AP-1; Transcriptome | 2015 |
Quercetin protects against perfluorooctanoic acid-induced liver injury by attenuating oxidative stress and inflammatory response in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Bile Acids and Salts; Caprylates; Chemical and Drug Induced Liver Injury; Cytokines; Fluorocarbons; Hepatocytes; Inflammation; Liver Function Tests; Male; Mice; Oxidative Stress; Quercetin | 2015 |
Perfluorooctanoic acid exposure induces endoplasmic reticulum stress in the liver and its effects are ameliorated by 4-phenylbutyrate.
Topics: Animals; Apoptosis; Caprylates; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Stress; Fluorocarbons; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Mice; Phenylbutyrates; Reactive Oxygen Species; Signal Transduction; Unfolded Protein Response | 2015 |
High perfluorooctanoic acid exposure induces autophagy blockage and disturbs intracellular vesicle fusion in the liver.
Topics: Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Caprylates; Cell Survival; Chemical and Drug Induced Liver Injury; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Environmental Pollutants; Fluorocarbons; Gene Expression Profiling; Gene Expression Regulation; Hep G2 Cells; Humans; Liver; Lysosomes; Male; Membrane Fusion Proteins; Mice, Inbred BALB C; Proteolysis; Random Allocation; RNA Interference | 2017 |
Comparative hepatotoxicity of 6:2 fluorotelomer carboxylic acid and 6:2 fluorotelomer sulfonic acid, two fluorinated alternatives to long-chain perfluoroalkyl acids, on adult male mice.
Topics: Alkanesulfonic Acids; Animals; Caprylates; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Fluorocarbons; Lipid Metabolism; Liver; Male; Mice; Organ Size; PPAR alpha; PPAR gamma; Sulfonic Acids | 2017 |
Self-reported health effects among community residents exposed to perfluorooctanoate.
Topics: Adolescent; Adult; Aged; Caprylates; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Cross-Sectional Studies; Dose-Response Relationship, Drug; Environmental Exposure; Female; Fluorocarbons; Humans; Male; Middle Aged; Ohio; Prevalence; Respiratory Tract Diseases; Surveys and Questionnaires; Water Pollution, Chemical; West Virginia | 2008 |
Investigation of the associations between low-dose serum perfluorinated chemicals and liver enzymes in US adults.
Topics: Adolescent; Adult; Alanine Transaminase; Caprylates; Chemical and Drug Induced Liver Injury; Environmental Exposure; Environmental Pollutants; Female; Fluorocarbons; gamma-Glutamyltransferase; Humans; Insulin Resistance; Liver; Male; Metabolic Syndrome; Middle Aged; Obesity; United States; Young Adult | 2010 |
Perfluorooctanoic acid-induced hepatic toxicity following 21-day oral exposure in mice.
Topics: Animals; Caprylates; Caspase 3; Chemical and Drug Induced Liver Injury; Cytokines; Dose-Response Relationship, Drug; Fluorocarbons; Liver; Liver Function Tests; Male; Mice; Mice, Inbred ICR; Organ Size; Toxicity Tests, Chronic | 2008 |