Compounds > perfluoro-1-4-7-10-13-pentaoxacyclopentadecane

perfluoro-1-4-7-10-13-pentaoxacyclopentadecane and Inflammation

perfluoro-1-4-7-10-13-pentaoxacyclopentadecane has been researched along with Inflammation* in 2 studies

Other Studies

2 other study(ies) available for perfluoro-1-4-7-10-13-pentaoxacyclopentadecane and Inflammation

Article	Year
Fluorine-19 MRI at 21.1 T: enhanced spin-lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo murine neuroinflammation. Magma (New York, N.Y.), 2019, Volume: 32, Issue:1 Fluorine MR would benefit greatly from enhancements in signal-to-noise ratio (SNR). This study examines the sensitivity gain of. We studied perfluoro-15-crown-5-ether (PFCE) at both field strengths (B. Compared to 9.4 T, an SNR gain of > 3 was observed for pure PFCE and > 2 for PFCE NPs at 21.1 T using 2D-FLASH. A dependency of. Enhanced SNR and T Topics: Animals; Brain; Calibration; Contrast Media; Crown Ethers; Encephalomyelitis, Autoimmune, Experimental; Female; Fluorine; Fluorine-19 Magnetic Resonance Imaging; Inflammation; Lymph Nodes; Mice; Nanoparticles; Radio Waves; Reproducibility of Results; Sensitivity and Specificity; Signal-To-Noise Ratio; Spin Labels; Spleen	2019
Accelerated fluorine-19 MRI cell tracking using compressed sensing. Magnetic resonance in medicine, 2013, Volume: 69, Issue:6 Cell tracking using perfluorocarbon labels and fluorine-19 (19F) MRI is a noninvasive approach to visualize and quantify cell populations in vivo. In this study, we investigated three-dimensional compressed sensing methods to accelerate 19F MRI data acquisition for cell tracking and evaluate the impact of acceleration on 19F signal quantification. We show that a greater than 8-fold reduction in imaging time was feasible without pronounced image degradation and with minimal impact on the image signal-to-noise ratio and 19F quantification accuracy. In 19F phantom studies, we show that apparent feature topology is maintained with compressed sensing reconstruction, and false positive signals do not appear in areas devoid of fluorine. We apply the three-dimensional compressed sensing 19F MRI methods to quantify the macrophage burden in a localized wounding-inflammation mouse model in vivo; at 8-fold image acceleration, the 19F signal distribution was accurately reproduced, with no loss in signal-to-noise ratio. Our results demonstrate that three-dimensional compressed sensing methods have potential for advancing in vivo 19F cell tracking for a wide range of preclinical and translational applications. Topics: Algorithms; Animals; Cell Tracking; Contrast Media; Crown Ethers; Data Compression; Female; Image Enhancement; Inflammation; Macrophages; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity	2013

Article

Year

Fluorine-19 MRI at 21.1 T: enhanced spin-lattice relaxation of perfluoro-15-crown-5-ether and sensitivity as demonstrated in ex vivo murine neuroinflammation.

Magma (New York, N.Y.), 2019, Volume: 32, Issue:1

Fluorine MR would benefit greatly from enhancements in signal-to-noise ratio (SNR). This study examines the sensitivity gain of. We studied perfluoro-15-crown-5-ether (PFCE) at both field strengths (B. Compared to 9.4 T, an SNR gain of > 3 was observed for pure PFCE and > 2 for PFCE NPs at 21.1 T using 2D-FLASH. A dependency of. Enhanced SNR and T

Topics: Animals; Brain; Calibration; Contrast Media; Crown Ethers; Encephalomyelitis, Autoimmune, Experimental; Female; Fluorine; Fluorine-19 Magnetic Resonance Imaging; Inflammation; Lymph Nodes; Mice; Nanoparticles; Radio Waves; Reproducibility of Results; Sensitivity and Specificity; Signal-To-Noise Ratio; Spin Labels; Spleen

2019

Accelerated fluorine-19 MRI cell tracking using compressed sensing.

Magnetic resonance in medicine, 2013, Volume: 69, Issue:6

Cell tracking using perfluorocarbon labels and fluorine-19 (19F) MRI is a noninvasive approach to visualize and quantify cell populations in vivo. In this study, we investigated three-dimensional compressed sensing methods to accelerate 19F MRI data acquisition for cell tracking and evaluate the impact of acceleration on 19F signal quantification. We show that a greater than 8-fold reduction in imaging time was feasible without pronounced image degradation and with minimal impact on the image signal-to-noise ratio and 19F quantification accuracy. In 19F phantom studies, we show that apparent feature topology is maintained with compressed sensing reconstruction, and false positive signals do not appear in areas devoid of fluorine. We apply the three-dimensional compressed sensing 19F MRI methods to quantify the macrophage burden in a localized wounding-inflammation mouse model in vivo; at 8-fold image acceleration, the 19F signal distribution was accurately reproduced, with no loss in signal-to-noise ratio. Our results demonstrate that three-dimensional compressed sensing methods have potential for advancing in vivo 19F cell tracking for a wide range of preclinical and translational applications.

Topics: Algorithms; Animals; Cell Tracking; Contrast Media; Crown Ethers; Data Compression; Female; Image Enhancement; Inflammation; Macrophages; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Pattern Recognition, Automated; Reproducibility of Results; Sensitivity and Specificity

2013