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peptide elongation factor 2 and Alzheimer Disease

peptide elongation factor 2 has been researched along with Alzheimer Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Ma, T1
Cox, AO; Furdui, CM; Holland, CE; Kasica, NP; Koscielniak, E; Lee, J; Ma, T; Ryazanov, AG; Wang, X; Wu, H; Yang, Q; Yang, W; Zhou, X; Zimmermann, HR1
Lizarazo, S; Tsai, NP; Yook, Y1
Ma, T; Ryazanov, AG; Yang, W; Zhou, X1
Beckelman, BC; Kasica, NP; Keene, CD; Ma, T; Ryazanov, AG; Yang, W; Zhou, X; Zimmermann, HR1
Chen, Y; Klann, E; Ma, T; Marambaud, P; Vingtdeux, V; Viollet, B; Zhao, H1
Alafuzoff, I; Li, X; Pei, JJ; Soininen, H; Winblad, B1
Bierer, L; Gotlib, J; Haroutunian, V; Johnson, G; Merril, C; Nairn, AC; Wallace, W1

Reviews

1 review(s) available for peptide elongation factor 2 and Alzheimer Disease

ArticleYear
Roles of eukaryotic elongation factor 2 kinase (eEF2K) in neuronal plasticity, cognition, and Alzheimer disease.
    Journal of neurochemistry, 2023, Volume: 166, Issue:1

    Topics: Alzheimer Disease; Cognition; Elongation Factor 2 Kinase; Humans; Neuronal Plasticity; Peptide Elongation Factor 2; Phosphorylation; Signal Transduction

2023

Other Studies

7 other study(ies) available for peptide elongation factor 2 and Alzheimer Disease

ArticleYear
Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer's disease model mice.
    Journal of neurochemistry, 2022, Volume: 160, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Elongation Factor 2 Kinase; Mice; Peptide Elongation Factor 2; Phosphorylation; Syndrome

2022
Amyloid beta induces Fmr1-dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2.
    Journal of cellular physiology, 2022, Volume: 237, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Eukaryotic Initiation Factor-2; Fragile X Mental Retardation Protein; Humans; Mice; Peptide Elongation Factor 2; Phosphorylation

2022
Suppression of the kinase for elongation factor 2 alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.
    Neurobiology of aging, 2021, Volume: 98

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Hippocampus; Imidazoles; Long-Term Potentiation; Mice, Transgenic; Neuronal Plasticity; Peptide Elongation Factor 2; Phosphorylation; Protein Biosynthesis; Receptor, Metabotropic Glutamate 5

2021
Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice.
    The Journal of clinical investigation, 2019, 02-01, Volume: 129, Issue:2

    Topics: Alzheimer Disease; Animals; Dendritic Spines; Disease Models, Animal; Elongation Factor 2 Kinase; Female; Humans; Long-Term Potentiation; Male; Mice; Mice, Knockout; Peptide Elongation Factor 2; Phosphorylation; Post-Synaptic Density; Signal Transduction

2019
Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Sep-03, Volume: 34, Issue:36

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Elongation Factor 2 Kinase; Excitatory Postsynaptic Potentials; Female; Hippocampus; Humans; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Peptide Elongation Factor 2; Presenilin-1; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Signal Transduction

2014
Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain.
    The FEBS journal, 2005, Volume: 272, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Alzheimer Disease; Autoantibodies; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Case-Control Studies; Cell Cycle Proteins; Elongation Factor 2 Kinase; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Male; Middle Aged; Peptide Elongation Factor 2; Phosphoproteins; Phosphorylation; Protein Kinases; TOR Serine-Threonine Kinases

2005
Increased phosphorylation of elongation factor 2 in Alzheimer's disease.
    Brain research. Molecular brain research, 1992, Volume: 15, Issue:3-4

    Topics: Adenosine Diphosphate Ribose; Alzheimer Disease; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Humans; Nerve Tissue Proteins; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoproteins; Phosphorylation; Polyribosomes; Protein Biosynthesis; Reticulocytes

1992