peplomycin and Vulvar-Neoplasms

peplomycin has been researched along with Vulvar-Neoplasms* in 2 studies

Trials

1 trial(s) available for peplomycin and Vulvar-Neoplasms

Article	Year
[Combination chemotherapy of peplomycin, vincristine, mitomycin C, and cisplatin in gynecologic carcinomas]. Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:10 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Genital Neoplasms, Female; Humans; Middle Aged; Mitomycin; Peplomycin; Uterine Cervical Neoplasms; Vincristine; Vulvar Neoplasms	1994

Other Studies

1 other study(ies) available for peplomycin and Vulvar-Neoplasms

Article	Year
[Combination chemotherapy with peplomycin, cis-platinum and mitomycin C in gynecologic cancer]. Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:11 Eight patients with gynecologic cancer (cervix: 6, corpus: 1 and vulva: 1) were treated with combination chemotherapy, PPM therapy consisting of continuously infused PEP 4mg/m2 days 1-5, CDDP 13 mg/m2 days 1-5, and MMC 3mg/m2 day 1. This was repeated every three to five weeks. Six of the eight patients were evaluable, two had a complete response and one had a partial response, for an overall response rate of 50%. Because of hematological toxicity, blood transfusion was carried out in four patients. Nephrotoxicity and pulmonary toxicity were slight. Nausea and vomiting were controlled with dexamethasone and domperidone. PPM therapy is considered to be an effective and useful combination chemotherapy for patients with gynecologic cancer. Topics: Adenocarcinoma; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Humans; Middle Aged; Mitomycin; Mitomycins; Peplomycin; Uterine Cervical Neoplasms; Uterine Neoplasms; Vulvar Neoplasms	1985

Article

Year

[Combination chemotherapy with peplomycin, cis-platinum and mitomycin C in gynecologic cancer].

Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:11

Eight patients with gynecologic cancer (cervix: 6, corpus: 1 and vulva: 1) were treated with combination chemotherapy, PPM therapy consisting of continuously infused PEP 4mg/m2 days 1-5, CDDP 13 mg/m2 days 1-5, and MMC 3mg/m2 day 1. This was repeated every three to five weeks. Six of the eight patients were evaluable, two had a complete response and one had a partial response, for an overall response rate of 50%. Because of hematological toxicity, blood transfusion was carried out in four patients. Nephrotoxicity and pulmonary toxicity were slight. Nausea and vomiting were controlled with dexamethasone and domperidone. PPM therapy is considered to be an effective and useful combination chemotherapy for patients with gynecologic cancer.

Topics: Adenocarcinoma; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Female; Humans; Middle Aged; Mitomycin; Mitomycins; Peplomycin; Uterine Cervical Neoplasms; Uterine Neoplasms; Vulvar Neoplasms

1985