pep005 and Granuloma

Granuloma faciale (GF) is a rare chronic inflammatory dermatosis of unknown etiology, characterized by leukocitoclastic vasculitis usually occurring on the face. We report a case of 60-years-old man with 3 year history of multiple actinic keratoses (AK) and persistent asymptomatic erythematous papules and plaques located over his left temporal region and the cheek: histopathology was consistent with GF. Herein we describe the successful treatment of the lesion with ingenol mebutate 0.015% gel focusing on the clinical, dermoscopic and histopathological findings of GF both before and after treatment.

Topics: Administration, Cutaneous; Biopsy; Dermatologic Agents; Dermoscopy; Diterpenes; Facial Dermatoses; Gels; Granuloma; Humans; Keratosis, Actinic; Male; Middle Aged; Remission Induction; Skin; Treatment Outcome