Page last updated: 2024-11-08

pentylenetetrazole and Water Intoxication

pentylenetetrazole has been researched along with Water Intoxication in 2 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Water Intoxication: A condition resulting from the excessive retention of water with sodium depletion.

Research Excerpts

ExcerptRelevanceReference
"Hypoosmolar treatment (water intoxication) was performed by the intraperitoneal administration of distilled water to a volume of 10% of the body weight; Six groups of rats were studied."1.32Influence of hypoosmolality on the blood-brain barrier permeability during epileptic seizures. ( Kaya, M; Küçük, M; Oztaş, B; Tuğran, N, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oztaş, B1
Kaya, M1
Küçük, M1
Tuğran, N1
Binder, DK1
Papadopoulos, MC1
Haggie, PM1
Verkman, AS1

Other Studies

2 other studies available for pentylenetetrazole and Water Intoxication

ArticleYear
Influence of hypoosmolality on the blood-brain barrier permeability during epileptic seizures.
    Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:4

    Topics: Animals; Blood-Brain Barrier; Convulsants; Osmosis; Pentylenetetrazole; Permeability; Rats; Rats, Wi

2003
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-15, Volume: 24, Issue:37

    Topics: Animals; Aquaporin 4; Aquaporins; Astrocytes; Brain Edema; Cerebral Cortex; Convulsants; Dextrans; D

2004