pentylenetetrazole has been researched along with Starvation in 5 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Starvation: Lengthy and continuous deprivation of food. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " infusion of phenobarbital to onset of loss of righting reflex showed that the starved animals required a larger body weight normalized dose and that they had higher phenobarbital concentrations in serum, serum water, brain and cerebrospinal fluid at the pharmacologic endpoint." | 7.67 | Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition. ( Levy, G; Wanwimolruk, S, 1987) |
| " infusion of phenobarbital to onset of loss of righting reflex showed that the starved animals required a larger body weight normalized dose and that they had higher phenobarbital concentrations in serum, serum water, brain and cerebrospinal fluid at the pharmacologic endpoint." | 3.67 | Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition. ( Levy, G; Wanwimolruk, S, 1987) |
| " The present study investigated the possible influence of the following factors on the level of melanotropic activity in whole brain, cerebral cortex, cerebellum, midbrain, and brainstem of mouse and rat: age, sex, starvation; and of the following hormones or drugs administered by the intraperitoneal or intracerebral route: norepinephrine, dihydroxyphenylalanine, pargyline, 6-hydroxy-dopamine, alpha-methyltyrosine methyl ester, reserpine, acetylcholine, pilocarpine, atropine, serotonin, p-chlorophenylalanine, pentobarbital, pentylenetetrazol, insulin, melatonin, and cycloheximide." | 3.65 | Melanotropic activity in extrahypophyseal regions of rodent brain: effect of age, hormones, and drugs. ( Chawla, RK; Katra, BS; Rudman, D, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BARTA, L | 1 |
| VEDRESNE TOTH, M | 1 |
| Rudman, D | 1 |
| Chawla, RK | 1 |
| Katra, BS | 1 |
| Wanwimolruk, S | 1 |
| Levy, G | 1 |
| Okabe, Y | 1 |
| Iizuka, H | 1 |
| Asahi, K | 1 |
| Yanagida, T | 1 |
| Krivanek, J | 1 |
| McGaugh, JL | 1 |
5 other studies available for pentylenetetrazole and Starvation
| Article | Year |
|---|---|
[Changes in the blood sugar level after Metrazol administration during starvation].
Topics: Blood Glucose; Humans; Hypoglycemia; Pancreatic Diseases; Pentylenetetrazole; Starvation | 1962 |
Melanotropic activity in extrahypophyseal regions of rodent brain: effect of age, hormones, and drugs.
Topics: Acetylcholine; Age Factors; Animals; Atropine; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Chick | 1975 |
Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition.
Topics: Animals; Blood Proteins; Body Weight; Central Nervous System; Diet; Dietary Carbohydrates; Dietary P | 1987 |
[Influence of food deprivation on efficacy and toxicity of drugs in mice].
Topics: Acetates; Aminopyrine; Analgesics; Animals; Anticonvulsants; Blood Glucose; Blood Proteins; Body Wei | 1969 |
Effects of pentylenetetrazol on memory storage in mice.
Topics: Animals; Cerebral Cortex; Discrimination Learning; Electroencephalography; Electrophysiology; Female | 1968 |