pentylenetetrazole has been researched along with Schizophrenia in 38 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In Akt1(-/-) and wild-type mice, seizures induced using pentylenetetrazol (a GABAAR antagonist) were measured, and GABAAR expression and GABAergic interneuron abundance in the brain were examined." | 1.43 | Akting up in the GABA hypothesis of schizophrenia: Akt1 deficiency modulates GABAergic functions and hippocampus-dependent functions. ( Chang, CY; Chen, YW; Lai, WS; Wang, TW, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (81.58) | 18.7374 |
| 1990's | 1 (2.63) | 18.2507 |
| 2000's | 2 (5.26) | 29.6817 |
| 2010's | 4 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cerletti, U | 1 |
| Bini, L | 1 |
| Forsingdal, A | 1 |
| Fejgin, K | 1 |
| Nielsen, V | 1 |
| Werge, T | 1 |
| Nielsen, J | 1 |
| Chang, CY | 1 |
| Chen, YW | 1 |
| Wang, TW | 1 |
| Lai, WS | 1 |
| BIANCHI, JA | 1 |
| CHIARELLO, CJ | 1 |
| Brigitta, B | 1 |
| István, B | 1 |
| Gábor, US | 1 |
| Gábor, G | 1 |
| COSSA, P | 1 |
| Baran, B | 1 |
| Bitter, I | 1 |
| Ungvari, GS | 1 |
| Gazdag, G | 1 |
| LEIBERMAN, DM | 1 |
| HOENIG, J | 1 |
| LAFON, R | 1 |
| PASSOUANT, P | 1 |
| MINVIELLE, J | 1 |
| FREUND, G | 1 |
| STOLC, V | 1 |
| POGADY, J | 1 |
| PLZAK, M | 1 |
| FISCHER, R | 1 |
| LEDEREROVA, E | 1 |
| TOMANOVA, M | 1 |
| MISUREC, J | 1 |
| NAHUNEK, K | 2 |
| WOLFF, K | 1 |
| FISCHER-WILLIAMS, M | 1 |
| COOPER, RA | 1 |
| FINNEGAN, BC | 1 |
| Koch, M | 1 |
| Ebert, U | 1 |
| Stephens, JH | 2 |
| Richard, P | 1 |
| McHugh, PR | 1 |
| Shakow, D | 2 |
| Barkai, AI | 1 |
| Berger, H | 1 |
| Villeneuve, A | 1 |
| Kazamatsuri, H | 1 |
| Hofling, CK | 1 |
| Winslow, WW | 1 |
| Kellner, R | 1 |
| Fink, M | 1 |
| Abrams, R | 1 |
| Tourney, G | 1 |
| Gabrynowicz, JW | 1 |
| Dumbrill, M | 1 |
| Uzunov, G | 1 |
| Iordanov, B | 1 |
| Doseva, I | 1 |
| Vikhliaev, IuI | 1 |
| Klygul', TA | 1 |
| Prokudin, VN | 1 |
| Adronati, SA | 1 |
| Varga, E | 1 |
| Haits, G | 1 |
| Schulz, H | 1 |
| Müller, J | 1 |
| Roth, B | 1 |
| Stein, J | 1 |
| Miller, JF | 1 |
| Fildisevski, P | 1 |
| Jus, A | 1 |
| Gerard, K | 1 |
| Ekiert, H | 1 |
| Piotrowski, A | 1 |
| Gogol, Z | 1 |
2 reviews available for pentylenetetrazole and Schizophrenia
| Article | Year |
|---|---|
THE CONFUSED GERIATRIC PATIENT.
Topics: Androgens; Dementia; Diagnosis, Differential; Estrogens; Geriatrics; Glutamates; Intracranial Arteri | 1964 |
Drug therapy.
Topics: Affective Symptoms; Antidepressive Agents; Butyrophenones; Cannabis; Clinical Trials as Topic; Human | 1972 |
3 trials available for pentylenetetrazole and Schizophrenia
| Article | Year |
|---|---|
[Fluorothyl: pharmacological aspect and clinical use].
Topics: Affective Symptoms; Animals; Bemegride; Bipolar Disorder; Central Nervous System Stimulants; Clinica | 1968 |
Drug therapy.
Topics: Affective Symptoms; Antidepressive Agents; Butyrophenones; Cannabis; Clinical Trials as Topic; Human | 1972 |
A clinical trial of leptazole with nicotinic acid in the management of psycho-geriatric patients.
Topics: Aged; Clinical Trials as Topic; Dementia; Female; Humans; Intracranial Arteriosclerosis; Male; Menta | 1968 |
34 other studies available for pentylenetetrazole and Schizophrenia
| Article | Year |
|---|---|
Electroshock
Topics: Animal Experimentation; Animals; Convulsants; Dogs; Electroconvulsive Therapy; Electroshock; Humans; | 2018 |
15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes.
Topics: Animals; Auditory Perceptual Disorders; Autistic Disorder; Behavior, Animal; Chromosome Deletion; Ch | 2016 |
Akting up in the GABA hypothesis of schizophrenia: Akt1 deficiency modulates GABAergic functions and hippocampus-dependent functions.
Topics: Animals; Brain Waves; Cell Count; Cell Differentiation; Convulsants; Female; GABA Antagonists; GABAe | 2016 |
Comparative results of electric shock and metrazol treatments of dementia praecox.
Topics: Convulsive Therapy; Electroconvulsive Therapy; Electroshock; Pentylenetetrazole; Schizophrenia; Ther | 1947 |
[The birth of convulsive therapy].
Topics: Biological Psychiatry; Brain; Camphor; Convulsants; Convulsive Therapy; Electroconvulsive Therapy; H | 2008 |
Respective indications of cures by insulin, cardiazolic and electric shocks.
Topics: Insulin; Mental Disorders; Pentylenetetrazole; Psychotic Disorders; Schizophrenia; Seizures; Therape | 1946 |
Respective indications of insulin therapy, cardiazoltherapy and electrochoctherapy.
Topics: Insulin; Mental Disorders; Pentylenetetrazole; Psychotic Disorders; Schizophrenia; Seizures; Therape | 1946 |
The birth of convulsive therapy revisited: a reappraisal of László Meduna's first cohort of patients.
Topics: Adolescent; Adult; Biological Psychiatry; Camphor; Convulsants; Convulsive Therapy; Female; History, | 2012 |
Photometrazol sensitivity in catatonic schizophrenia.
Topics: Humans; Pentylenetetrazole; Schizophrenia; Schizophrenia, Catatonic | 1953 |
[EEG study of the sleep of hebephreno-catatonic schizophrenics; comparison with resting curve and cardiazol activation].
Topics: Catatonia; Electroencephalography; Humans; Pentylenetetrazole; Schizophrenia; Sleep | 1955 |
[Studies of the mechanism of action of cardiazol in convulsive therapy].
Topics: Convulsive Therapy; Humans; Pentylenetetrazole; Schizophrenia | 1955 |
The effect of insulin and cardiazoleshock on protein-bound iodine in blood, studied in schizophrenic patients.
Topics: Blood Proteins; Convulsive Therapy; Humans; Insulin; Iodides; Iodine; Pentylenetetrazole; Schizophre | 1960 |
[PHOTOMETRAZOLE THRESHOLD DURING THERAPY WITH VARIOUS ANTIDEPRESSIVE AGENTS].
Topics: Antidepressive Agents; Imipramine; Mental Disorders; Neurasthenia; Pentylenetetrazole; Psychotic Dis | 1963 |
[PHOTOMETRAZOLE THRESHOLD DURING THERAPY WITH VARIOUS ANTIDEPRESSIVE AGENTS].
Topics: Antidepressive Agents; Imipramine; Mental Disorders; Neurasthenia; Pentylenetetrazole; Psychotic Dis | 1963 |
DEPTH RECORDING FROM THE HUMAN BRAIN IN EPILEPSY.
Topics: Adolescent; Amygdala; Astrocytoma; Bemegride; Caudate Nucleus; Child; Chlorpromazine; Electroencepha | 1963 |
LEPTAZOL THERAPY.
Topics: Convulsive Therapy; Drug Therapy; Pentylenetetrazole; Schizophrenia; Toxicology | 1965 |
[Study on the pentazole-neuroleptic and neuroleptic treatment of schizophrenia].
Topics: Antipsychotic Agents; Chlorpromazine; Pentylenetetrazole; Reserpine; Schizophrenia | 1961 |
Deficient sensorimotor gating following seizures in amygdala-kindled rats.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Cues; Disease Models, Animal; Electri | 1998 |
Long-term follow-up of patients with a diagnosis of paranoid state and hospitalized, 1913 to 1940.
Topics: Adult; Electroconvulsive Therapy; Female; Follow-Up Studies; Hallucinations; Hospital Records; Hospi | 2000 |
Psychological deficit in schizophrenia.
Topics: Aspirations, Psychological; Association; Autonomic Nervous System; Cognition; Cooperative Behavior; | 1977 |
Combined electroconvulsive and drug therapy.
Topics: Anesthesia; Apnea; Atropine; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect | 1985 |
On the electroencephalogram of man. Fourteenth report.
Topics: Adolescent; Adult; Anesthesia; Attention; Cerebral Cortex; Electrodes; Electroencephalography; Epile | 1969 |
EEG activation with Dimefline hydrochloride.
Topics: Adolescent; Adult; Alcoholism; Central Nervous System Stimulants; Craniocerebral Trauma; Electroence | 1969 |
Answers to questions frequently asked about ECT.
Topics: Age Factors; Anesthesia, Intravenous; Brain Damage, Chronic; Brain Neoplasms; Depression; Electrocon | 1972 |
A history of therapeutic fashions in psychiatry, 1800-1966.
Topics: Convulsive Therapy; Electroconvulsive Therapy; History, 19th Century; History, 20th Century; Hospita | 1967 |
Some observations on the psychology (and some fewer, on the biology) of schizophrenia.
Topics: Blood Pressure; Body Temperature; Galvanic Skin Response; Heart Rate; Humans; Insulin; Oxygen Consum | 1971 |
[Effect of some stabilizers on erythrocyte membrane permeability in schizophrenia].
Topics: Cell Membrane Permeability; Erythrocytes; Humans; Pentylenetetrazole; Phosphorus Isotopes; Schizophr | 1969 |
Long-term course and prognosis in schizophrenia.
Topics: Adolescent; Adult; Aged; Child; Convulsive Therapy; Cross-Cultural Comparison; Electroconvulsive The | 1970 |
[Comparison of the characteristics of the effect of tranquilizing agents under experimental and clinical conditions].
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Diseases; Chlordiazepoxide; Depre | 1971 |
Therapeutic efficacy and the treatment of psychoses over the last three decades.
Topics: Adult; Bipolar Disorder; Convulsive Therapy; Electroconvulsive Therapy; Female; Humans; Imipramine; | 1968 |
Bioelectrically controlled convulsion treatment of endogenous psychoses under general anaesthesia and muscular relaxation. I. Changes of the passive EEG.
Topics: Adult; Aged; Anesthesia, General; Bipolar Disorder; Convulsive Therapy; Electrocardiography; Electro | 1968 |
Management of chronic mental patients.
Topics: Adult; Aged; Humans; Intracranial Arteriosclerosis; Male; Mental Disorders; Middle Aged; Nicotinic A | 1965 |
[Activation of EEG by cardiazol and its role in the differentiation of some clinical pictures in psychiatry].
Topics: Electroencephalography; Epilepsy, Temporal Lobe; Humans; Pentylenetetrazole; Schizophrenia | 1964 |
[Photo-cardiazol threshold in schizophrenics with a familial history].
Topics: Adult; Female; Humans; Light; Male; Pentylenetetrazole; Schizophrenia | 1966 |