pentylenetetrazole has been researched along with Neuromuscular Diseases in 1 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Neuromuscular Diseases: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For the former, the MES test, clonic seizures induced by pentylenetetrazol, 90 mg/kg, s." | 1.26 | Differential selectivity of several barbiturates on experimental seizures and neurotoxicity in the mouse. ( Blake, GJ; Gilbert, MB; Raines, A; Richardson, B, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raines, A | 1 |
| Blake, GJ | 1 |
| Richardson, B | 1 |
| Gilbert, MB | 1 |
1 other study available for pentylenetetrazole and Neuromuscular Diseases
| Article | Year |
|---|---|
Differential selectivity of several barbiturates on experimental seizures and neurotoxicity in the mouse.
Topics: Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Male; Mice; Neuromuscular Disease | 1979 |