pentylenetetrazole has been researched along with Necrosis in 1 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epilepsy seizures was induced by repetitive injections of pentylenetetrazol at a dose of 37 mg per kg." | 1.51 | Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice. ( Cheng, Y; Ding, H; Li, J; Mai, Q; Tang, L; Wang, H; Xiao, Y; Zeng, X; Zhang, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, Y | 1 |
| Mai, Q | 1 |
| Zeng, X | 1 |
| Wang, H | 1 |
| Xiao, Y | 1 |
| Tang, L | 1 |
| Li, J | 1 |
| Zhang, Y | 1 |
| Ding, H | 1 |
1 other study available for pentylenetetrazole and Necrosis
| Article | Year |
|---|---|
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Triphosphate; Animals; Catalase; Exploratory Behavior; Female | 2019 |