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pentylenetetrazole and Nasal Obstruction

pentylenetetrazole has been researched along with Nasal Obstruction in 1 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Nasal Obstruction: Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.

Research Excerpts

ExcerptRelevanceReference
"Our data revealed that seizure threshold was increased 6 to 72 hours after nasal obstruction, reaching a peak 48 hours afterward, compared with either control or sham-operated mice (P<0."5.35Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels. ( Dehpour, AR; Fakhimi, A; Ghasemi, M; Niaki, SE; Shafaroodi, H; Shakiba, B, 2008)
"Our data revealed that seizure threshold was increased 6 to 72 hours after nasal obstruction, reaching a peak 48 hours afterward, compared with either control or sham-operated mice (P<0."1.35Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels. ( Dehpour, AR; Fakhimi, A; Ghasemi, M; Niaki, SE; Shafaroodi, H; Shakiba, B, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Niaki, SE1
Shafaroodi, H1
Ghasemi, M1
Shakiba, B1
Fakhimi, A1
Dehpour, AR1

Other Studies

1 other study available for pentylenetetrazole and Nasal Obstruction

ArticleYear
Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels.
    Epilepsy & behavior : E&B, 2008, Volume: 13, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Animals; Brain; Carbon Dioxide; Diazoxide; Dose-Respon

2008