pentylenetetrazole has been researched along with Morphine Abuse in 5 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine dependence increased a PTZ-induced long-term potentiation (LTP) of the population spike in CA1 in vitro." | 7.75 | Morphine dependence increases the response to a brief pentylenetetrazol administration in rat hippocampal CA1 in vitro. ( Fathollahi, Y; Jafarzadeh, Z; Omrani, A; Salmani, ME; Salmanzadeh, F; Semnanian, S, 2009) |
| "Morphine dependence increased a PTZ-induced long-term potentiation (LTP) of the population spike in CA1 in vitro." | 3.75 | Morphine dependence increases the response to a brief pentylenetetrazol administration in rat hippocampal CA1 in vitro. ( Fathollahi, Y; Jafarzadeh, Z; Omrani, A; Salmani, ME; Salmanzadeh, F; Semnanian, S, 2009) |
| "The role of morphine-dependence on the seizure susceptibility has been evaluated with models of pentylenetetrazol (PTZ)-kindling and acute convulsions induced by PTZ, N-methyl-D-aspartic acid (NMDA), picrotoxin and caffeine in adult male rats." | 1.31 | Chemical kindling and seizure susceptibility in morphine dependent rats. ( Atapour, N; Kalantaripour, TP; Niazi, M; Nourpanah, M, 2000) |
| "Morphine dependence was induced in 90-day-old mice (weighing 29 to 32 g) by a 6-day schedule of twice daily i." | 1.27 | Effect of different convulsant drugs on some seizure parameters in morphine-dependent mice. ( Aleman, V; de Muñoz, DM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jafarzadeh, Z | 1 |
| Fathollahi, Y | 1 |
| Semnanian, S | 1 |
| Omrani, A | 1 |
| Salmanzadeh, F | 1 |
| Salmani, ME | 1 |
| Aleman, V | 1 |
| de Muñoz, DM | 1 |
| Emmett-Oglesby, MW | 1 |
| Harris, CM | 1 |
| Lane, JD | 1 |
| Lal, H | 1 |
| Mucha, RF | 1 |
| Fassos, FF | 1 |
| Perl, FM | 1 |
| Atapour, N | 1 |
| Kalantaripour, TP | 1 |
| Nourpanah, M | 1 |
| Niazi, M | 1 |
5 other studies available for pentylenetetrazole and Morphine Abuse
| Article | Year |
|---|---|
Morphine dependence increases the response to a brief pentylenetetrazol administration in rat hippocampal CA1 in vitro.
Topics: Animals; Convulsants; Disease Models, Animal; Drug Interactions; Electric Stimulation; Evoked Potent | 2009 |
Effect of different convulsant drugs on some seizure parameters in morphine-dependent mice.
Topics: 3-Mercaptopropionic Acid; 4-Aminopyridine; Aminopyridines; Animals; Bicuculline; Brain; Convulsants; | 1983 |
Withdrawal from morphine generalizes to a pentylenetetrazol stimulus.
Topics: Animals; Discrimination, Psychological; Humans; Male; Morphine; Morphine Dependence; Pentylenetetraz | 1984 |
Withdrawal-like effects of pentylenetetrazol and valproate in the naive organism: a model of motivation produced by opiate withdrawal?
Topics: Animals; Avoidance Learning; Conditioning, Classical; Disease Models, Animal; Dose-Response Relation | 1995 |
Chemical kindling and seizure susceptibility in morphine dependent rats.
Topics: Animals; Caffeine; Convulsants; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Ago | 2000 |