pentylenetetrazole has been researched along with Metabolic Acidosis in 4 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most seizures stop spontaneously; however, the molecular mechanisms that terminate seizures remain unknown." | 1.35 | Seizure termination by acidosis depends on ASIC1a. ( Albert, GW; Howard, MA; Schnizler, MK; Severson, MA; Welsh, MJ; Wemmie, JA; Ziemann, AE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ziemann, AE | 1 |
| Schnizler, MK | 1 |
| Albert, GW | 1 |
| Severson, MA | 1 |
| Howard, MA | 1 |
| Welsh, MJ | 1 |
| Wemmie, JA | 1 |
| Howse, DC | 2 |
| Caspers, H | 1 |
| Speckmann, EJ | 1 |
| Plum, F | 1 |
| Duffy, TE | 1 |
4 other studies available for pentylenetetrazole and Metabolic Acidosis
| Article | Year |
|---|---|
Seizure termination by acidosis depends on ASIC1a.
Topics: Acid Sensing Ion Channels; Acidosis; Analysis of Variance; Animals; Animals, Newborn; Behavior, Anim | 2008 |
Metabolic responses to status epilepticus in the rat, cat, and mouse.
Topics: Acidosis; Animals; Anticonvulsants; Blood Pressure; Brain Chemistry; Cats; Electroencephalography; F | 1979 |
Cerebral pO 2 , pCO 2 and pH: changes during convulsive activity and their significance for spontaneous arrest of seizures.
Topics: Acidosis; Action Potentials; Animals; Carbon Dioxide; Cerebral Cortex; Electric Stimulation; Electro | 1972 |
Metabolic effects of seizures.
Topics: Acidosis; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bicarbonates; Blood Flow Velocity; | 1974 |