pentylenetetrazole has been researched along with Magnesium Deficiency in 5 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Excerpt | Relevance | Reference |
|---|---|---|
| " No differences in convulsive thresholds to Metrazol were obtained, however, between untreated Swiss-Webster mice and mice of the same strain made audiosuseptible by rubidium chloride intake or magnesium deficiency." | 3.66 | Metrazol thresholds in inbred and non-inbred audiosensitive mice. ( Alexander, GJ; Alexander, RB; Kopeloff, LM, 1981) |
| "Hydrogen sulfide (H2 S) is a gas transmitter that may mediate cerebral ischemic injury." | 1.40 | Aggravation of seizure-like events by hydrogen sulfide: involvement of multiple targets that control neuronal excitability. ( Chen, JG; Guan, XL; He, JG; Hu, ZL; Luo, Y; Wang, F; Wu, PF; Xiao, W; Zhang, JT; Zhou, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Guo, Y | 1 |
| He, L | 1 |
| Chen, C | 1 |
| Luo, J | 1 |
| Ma, Y | 1 |
| Li, J | 1 |
| Yang, Y | 1 |
| Yang, Q | 1 |
| Du, C | 1 |
| Zhang, Y | 1 |
| Li, Z | 1 |
| Xu, X | 1 |
| Tian, X | 1 |
| Wang, X | 1 |
| Luo, Y | 1 |
| Wu, PF | 1 |
| Zhou, J | 1 |
| Xiao, W | 1 |
| He, JG | 1 |
| Guan, XL | 1 |
| Zhang, JT | 1 |
| Hu, ZL | 1 |
| Wang, F | 1 |
| Chen, JG | 1 |
| Alexander, GJ | 1 |
| Kopeloff, LM | 1 |
| Alexander, RB | 1 |
| Spasov, AA | 1 |
| Iezhitsa, IN | 1 |
| Kharitonova, MV | 1 |
| Kravchenko, MS | 1 |
| Vamecq, J | 1 |
| Bac, P | 1 |
| Herrenknecht, C | 1 |
| Maurois, P | 1 |
| Delcourt, P | 1 |
| Stables, JP | 1 |
5 other studies available for pentylenetetrazole and Magnesium Deficiency
| Article | Year |
|---|---|
Overexpression of miRNA-137 in the brain suppresses seizure activity and neuronal excitability: A new potential therapeutic strategy for epilepsy.
Topics: Adolescent; Adult; Animals; Brain; Disease Models, Animal; Epilepsy; Female; Humans; Inhibitory Post | 2018 |
Aggravation of seizure-like events by hydrogen sulfide: involvement of multiple targets that control neuronal excitability.
Topics: 4-Aminopyridine; Animals; Disease Models, Animal; Entorhinal Cortex; Hydrogen Sulfide; Magnesium Def | 2014 |
Metrazol thresholds in inbred and non-inbred audiosensitive mice.
Topics: Acoustic Stimulation; Animals; Convulsants; Epilepsy, Reflex; Magnesium Deficiency; Male; Mice; Pent | 1981 |
Effect of magnesium chloride and magnesium L-aspartate on seizure threshold in rats under conditions of dietary magnesium deficiency.
Topics: Animals; Anticonvulsants; Aspartic Acid; Magnesium Chloride; Magnesium Deficiency; Male; Pentylenete | 2007 |
Synthesis and anticonvulsant and neurotoxic properties of substituted N-phenyl derivatives of the phthalimide pharmacophore.
Topics: Administration, Oral; Animals; Anticonvulsants; Batrachotoxins; Cerebral Cortex; Convulsants; Electr | 2000 |