pentylenetetrazole has been researched along with Kidney Diseases in 2 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Topiramate, a voltage-gated calcium channel inhibitor, has an evident effect in the treatment of childhood epilepsy; however, topiramate may cause nephrotoxicity." | 3.74 | Topiramate and vitamin e modulate antioxidant enzyme activities, nitric oxide and lipid peroxidation levels in pentylenetetrazol-induced nephrotoxicity in rats. ( Armagan, A; Bülbül, M; Kutluhan, S; Naziroglu, M; Soyupek, S; Vural, H; Yilmaz, M; Yilmaz, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armagan, A | 1 |
| Kutluhan, S | 1 |
| Yilmaz, M | 1 |
| Yilmaz, N | 1 |
| Bülbül, M | 1 |
| Vural, H | 1 |
| Soyupek, S | 1 |
| Naziroglu, M | 1 |
| Ramzan, I | 1 |
| Levy, G | 1 |
2 other studies available for pentylenetetrazole and Kidney Diseases
| Article | Year |
|---|---|
Topiramate and vitamin e modulate antioxidant enzyme activities, nitric oxide and lipid peroxidation levels in pentylenetetrazol-induced nephrotoxicity in rats.
Topics: Animals; Anticonvulsants; Antioxidants; Catalase; Dose-Response Relationship, Drug; Drug Therapy, Co | 2008 |
Kinetics of drug action in disease states. XXXIII: Disparate effects of pentylenetetrazol in rats as a function of renal disease model and pharmacologic endpoint.
Topics: Animals; Female; Kidney Diseases; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Uranyl N | 1989 |