pentylenetetrazole has been researched along with Ischemia in 4 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report herein the influence of nimodipine, a selective central nervous system calcium channel blocker, in 60 rabbits with seizures that had been induced through ischemia, postischemia reperfusion, pentylenetetrazol, and bicuculline." | 3.67 | Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents. ( Anderson, RE; Meyer, FB; Sharbrough, FW; Sundt, TM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Zhang, X | 1 |
| Wu, Y | 1 |
| Zhao, B | 1 |
| Liu, X | 1 |
| Pan, Y | 1 |
| Liu, Y | 1 |
| Ding, Y | 1 |
| Qiu, M | 1 |
| Wang, YZ | 1 |
| Zhao, G | 1 |
| Meldrum, BS | 1 |
| Papy, JJ | 1 |
| Toure, MF | 1 |
| Brierley, JB | 1 |
| Meyer, FB | 1 |
| Anderson, RE | 1 |
| Sundt, TM | 1 |
| Sharbrough, FW | 1 |
| Myers, RR | 1 |
| Stockard, JJ | 1 |
| Fleming, NI | 1 |
| France, CJ | 1 |
| Bickford, RG | 1 |
4 other studies available for pentylenetetrazole and Ischemia
| Article | Year |
|---|---|
Wnt/β-catenin signaling mediates the seizure-facilitating effect of postischemic reactive astrocytes after pentylenetetrazole-kindling.
Topics: Animals; Astrocytes; beta Catenin; Ischemia; Male; Mice, Inbred C57BL; Pentylenetetrazole; Seizures; | 2016 |
Four models for studying cerebral lesions secondary to epileptic seizures.
Topics: Animals; Astrocytes; Bicuculline; Blood Gas Analysis; Blood Glucose; Blood Pressure; Body Temperatur | 1975 |
Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents.
Topics: Animals; Anticonvulsants; Bicuculline; Calcium Channel Blockers; Central Nervous System; Convulsants | 1986 |
The use of on-line telephonic computer analysis of the E.E.G. in anaesthesia.
Topics: Anesthesia; Anesthesia, Inhalation; Animals; Cerebrovascular Circulation; Communication; Computers; | 1973 |