pentylenetetrazole has been researched along with Infarction, Middle Cerebral Artery in 3 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine (3,5-DBr-D: -Tyr) were studied in rat models of stroke and epileptic seizures caused by middle cerebral artery occlusion (MCAo) through respective intracerebral injection of endothelin-1 (ET-1) and intraperitoneal (i." | 7.77 | Halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine produces beneficial effects in experimental stroke and seizures. ( Cao, W; Glushakov, A; Martynyuk, AE; Mecca, AP; Seubert, CN; Shah, HP; Shi, P; Sumners, C, 2011) |
| "The effects of the halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine (3,5-DBr-D: -Tyr) were studied in rat models of stroke and epileptic seizures caused by middle cerebral artery occlusion (MCAo) through respective intracerebral injection of endothelin-1 (ET-1) and intraperitoneal (i." | 3.77 | Halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine produces beneficial effects in experimental stroke and seizures. ( Cao, W; Glushakov, A; Martynyuk, AE; Mecca, AP; Seubert, CN; Shah, HP; Shi, P; Sumners, C, 2011) |
| "Finally, we showed that kainate induced seizures and glycemia were not modified by spadin treatments." | 1.38 | Spadin as a new antidepressant: absence of TREK-1-related side effects. ( Borsotto, M; Coppola, T; Gandin, C; Heurteaux, C; Labbal, F; Mazella, J; Moha Ou Maati, H; Veyssiere, J; Widmann, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, W | 1 |
| Glushakov, A | 1 |
| Shah, HP | 1 |
| Mecca, AP | 1 |
| Sumners, C | 1 |
| Shi, P | 1 |
| Seubert, CN | 1 |
| Martynyuk, AE | 1 |
| Moha Ou Maati, H | 1 |
| Veyssiere, J | 1 |
| Labbal, F | 1 |
| Coppola, T | 1 |
| Gandin, C | 1 |
| Widmann, C | 1 |
| Mazella, J | 1 |
| Heurteaux, C | 1 |
| Borsotto, M | 1 |
| Reed, RR | 1 |
| Ciesel, C | 1 |
| Owens, G | 1 |
3 other studies available for pentylenetetrazole and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Halogenated aromatic amino acid 3,5-dibromo-D: -tyrosine produces beneficial effects in experimental stroke and seizures.
Topics: Animals; Blood Pressure; Brain; Caspase 3; Disease Models, Animal; Endothelin-1; Epilepsy; Heart Rat | 2011 |
Spadin as a new antidepressant: absence of TREK-1-related side effects.
Topics: Animals; Antidepressive Agents; Biophysical Phenomena; Blood Glucose; Brain Infarction; CD8 Antigens | 2012 |
Induced seizures as therapy of experimental strokes in dogs.
Topics: Animals; Blood Pressure; Brain; Carotid Stenosis; Convulsants; Disease Models, Animal; Dogs; Electri | 1971 |