Page last updated: 2024-11-08

pentylenetetrazole and Inadequate Sleep

pentylenetetrazole has been researched along with Inadequate Sleep in 4 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Research Excerpts

ExcerptRelevanceReference
"Sleep deprivation has been shown to be an activator of seizures in clinical and animal studies."1.40Pentylenetetrazol-induced seizures are exacerbated by sleep deprivation through orexin receptor-mediated hippocampal cell proliferation. ( Liu, XM; Ni, LY; Song, Y; Tang, JY; Zhu, MJ, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reichert, S1
Pavón Arocas, O1
Rihel, J1
Ben, J1
Marques Gonçalves, F1
Alexandre Oliveira, P1
Vieira Peres, T1
Hohl, A1
Bainy Leal, R1
Abrão Cavalheiro, E1
Daniel Schroder Prediger, R1
Walz, R1
Ni, LY1
Zhu, MJ1
Song, Y1
Liu, XM1
Tang, JY1
Vale, NB1
Leite, JR1

Other Studies

4 other studies available for pentylenetetrazole and Inadequate Sleep

ArticleYear
The Neuropeptide Galanin Is Required for Homeostatic Rebound Sleep following Increased Neuronal Activity.
    Neuron, 2019, 10-23, Volume: 104, Issue:2

    Topics: 4-Aminopyridine; Aconitine; Animals; Caffeine; Extracellular Signal-Regulated MAP Kinases; GABA Anta

2019
Brain MAPKs levels are differentially associated with seizures threshold and severity progression in pentylenetetrazole-kindled mice.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:9

    Topics: Animals; Brain; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protei

2013
Pentylenetetrazol-induced seizures are exacerbated by sleep deprivation through orexin receptor-mediated hippocampal cell proliferation.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:2

    Topics: Animals; Benzoxazoles; CA3 Region, Hippocampal; Cell Proliferation; Convulsants; Dentate Gyrus; Hipp

2014
Decreased susceptibility to local anesthetics-induced convulsions after paradoxical sleep deprivation.
    Psychopharmacology, 1988, Volume: 94, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Lidocaine; Male; Mice; Pentylenetetrazole; Seizures; Sleep

1988