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pentylenetetrazole and Hypotension

pentylenetetrazole has been researched along with Hypotension in 6 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Fluorometry and dual-wave-length spectrophotometry were used to detect transitory shifts in the redox state of mitochondrial NADH and cytochrome aa3 in the exposed cerebral cortex of anesthetized paralyzed cats as seizures were induced with pentylenetetrazol."3.66Redox transitions in mitochondria of cat cerebral cortex with seizures and hemorrhagic hypotension. ( Hempel, FG; Kariman, K; Saltzman, HA, 1980)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MESSERICH, J1
NUSSER, E1
DONATH, H1
Hempel, FG1
Kariman, K1
Saltzman, HA1
Vern, B1
Schuette, WH1
Whitehouse, WC1
Mutsuga, N1
Kramer, HJ1
Rambauske, F1

Other Studies

6 other studies available for pentylenetetrazole and Hypotension

ArticleYear
[OUR EXPERIENCES WITH THE CENTRAL AND PERIPHERAL CIRCULATORY STIMULANT SYMPATOCARD].
    Die Medizinische Welt, 1963, Nov-30, Volume: 48

    Topics: Balneology; Central Nervous System Agents; Central Nervous System Stimulants; Convalescence; Geriatr

1963
[ON THE EFFECT OF A COMBINATION OF SYMPATHOL AND CARDIAZOL IN PATIENTS WITH HYPOTONIC CIRCULATORY REGULATION DISORDERS].
    Medizinische Klinik, 1964, Dec-04, Volume: 59

    Topics: Blood Pressure; Drug Synergism; Drug Therapy; Heart Rate; Humans; Hypotension; Pentylenetetrazole; P

1964
Redox transitions in mitochondria of cat cerebral cortex with seizures and hemorrhagic hypotension.
    The American journal of physiology, 1980, Volume: 238, Issue:2

    Topics: Animals; Cats; Cerebral Cortex; Cytochromes; Hemorrhage; Hypotension; Mitochondria; NAD; Oxidation-R

1980
Cortical oxygen consumption and NADH flourescence during metrazol seizures in normotensive and hypotensive cats.
    Experimental neurology, 1976, Volume: 52, Issue:1

    Topics: Animals; Blood Pressure; Cats; Cerebral Cortex; Fluorescence; Fluorometry; Hypotension; NAD; Oxygen

1976
[Drug therapy of hypotension].
    Deutsche medizinische Wochenschrift (1946), 1978, Dec-01, Volume: 103, Issue:48

    Topics: Amphetamine; Benzamides; Ephedrine; Humans; Hypotension; Methamphetamine; Mineralocorticoids; Pentyl

1978
[The management of hypotension using Sympatocard].
    Wiener medizinische Wochenschrift (1946), 1967, Dec-09, Volume: 117, Issue:49

    Topics: Blood Pressure; Female; Humans; Hypotension; Male; Pentylenetetrazole; Synephrine

1967