Page last updated: 2024-11-08

pentylenetetrazole and Hypoglycemia

pentylenetetrazole has been researched along with Hypoglycemia in 7 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.

Research Excerpts

ExcerptRelevanceReference
"The sensitivity to insulin hypoglycemic convulsions has been shown to decrease at early times (16 and 24 hr) and increase at later times (1 week) after gold thioglucose (GTG) treatment."1.26Change in sensitivity to insulin hypoglycemic convulsions after gold thioglucose treatment: time course of development. ( Fish, KW; Holliday, JF; Luby, JL; Marrazzi, MA, 1981)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BARTA, L1
VEDRESNE TOTH, M1
Luby, JL1
Holliday, JF3
Fish, KW2
Marrazzi, MA3
Churchill, B1
Kaul, CL1
David, J1
Grewal, RS1
Kokka, N1
Garcia, JF1
George, R1
Elliot, HW1
Roberge, A1
Charbonneau, R1

Other Studies

7 other studies available for pentylenetetrazole and Hypoglycemia

ArticleYear
[Changes in the blood sugar level after Metrazol administration during starvation].
    Gyermekgyogyaszat : az Orvosegeszsegugyi Szakszervezet Gyermekorvos Szakcsoportjanak folyoirata = Pediatriia, 1962, Volume: 13

    Topics: Blood Glucose; Humans; Hypoglycemia; Pancreatic Diseases; Pentylenetetrazole; Starvation

1962
Change in sensitivity to insulin hypoglycemic convulsions after gold thioglucose treatment: time course of development.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Animals; Aurothioglucose; Body Weight; Brain; Female; Gold; Gold Sodium Thiomalate; Hypoglycemia; In

1981
Comparison of insulin hypoglycemia-induced and fluoroacetate-induced convulsions in gold thioglucose lesioned mice.
    Biochemical pharmacology, 1981, Dec-01, Volume: 30, Issue:23

    Topics: Animals; Aurothioglucose; Blood Glucose; Body Weight; Citrates; Citric Acid; Female; Fluoroacetates;

1981
Effects of bipiperidyl mustard (BPM) lesions on insulin hypoglycemic convulsions.
    Physiology & behavior, 1982, Volume: 29, Issue:3

    Topics: Animals; Aurothioglucose; Body Weight; Eating; Female; Hypoglycemia; Insulin; Mice; Mice, Inbred CBA

1982
The incidence of electroshock and pentylenetetrazole (Metrazol) induced convulsions in hypoglycaemic and acute and chronic hyperglycaemic states in mice.
    Pharmacological research communications, 1980, Volume: 12, Issue:8

    Topics: Animals; Electroshock; Hyperglycemia; Hypoglycemia; Male; Maximum Allowable Concentration; Mice; Pen

1980
Growth hormone and ACTH secretion: evidence for an inverse relationship in rats.
    Endocrinology, 1972, Volume: 90, Issue:3

    Topics: Adrenocorticotropic Hormone; Amphetamine; Animals; Blood Glucose; Cold Temperature; Dexamethasone; E

1972
Protective effects of arginine against hepatic coma, insulin shock and epilepsy.
    Life sciences, 1969, Apr-15, Volume: 8, Issue:8

    Topics: Ammonia; Animals; Arginine; Brain Chemistry; Epilepsy, Absence; Hepatic Encephalopathy; Hypoglycemia

1969