pentylenetetrazole has been researched along with Encephalitis in 8 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Encephalitis: Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was conducted to evaluate the effect of embelin (EMB) on various epileptic models and related brain inflammation." | 8.02 | Embelin ameliorates cognitive dysfunction and progression of kindling in pentylenetetrazol-induced kindling in mice by attenuating brain inflammation. ( Agarwal, NB; Hoda, U; Jain, GK; Jain, S; Samim, M, 2021) |
| "Evidence suggests that improving brain inflammation can inhibit the epileptogenesis process and help the emergence of new drugs for the treatment of epilepsy." | 5.72 | Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model. ( Akkaya, R; Filiz, AK; Karabulut, S, 2022) |
| "Seizures are sustained neuronal hyperexcitability in brain that result in loss of consciousness and injury." | 5.48 | Activation of BDNF-TrkB signaling pathway-regulated brain inflammation in pentylenetetrazole-induced seizures in zebrafish. ( Han, L; He, Q; Ji, X; Jin, M; Liu, K; Sheng, W, 2018) |
| "RESV modified brain inflammation during epileptogenesis and found to possess nootropic activity in the kindled mice." | 5.46 | Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice. ( Agarwal, NB; Hoda, U; Parvez, S; Raisuddin, S; Vohora, D, 2017) |
| "Erythropoietin (EPO) suppresses epileptic seizures, but the mechanism is unclear." | 5.40 | Erythropoietin pretreatment suppresses seizures and prevents the increase in inflammatory mediators during pentylenetetrazole-induced generalized seizures. ( Akgün-Dar, K; Albeniz, I; Bahçekapılı, N; Kandil, A; Kapucu, A; Üzüm, G; Yağız, O, 2014) |
| "This study was conducted to evaluate the effect of embelin (EMB) on various epileptic models and related brain inflammation." | 4.02 | Embelin ameliorates cognitive dysfunction and progression of kindling in pentylenetetrazol-induced kindling in mice by attenuating brain inflammation. ( Agarwal, NB; Hoda, U; Jain, GK; Jain, S; Samim, M, 2021) |
| "Evidence suggests that improving brain inflammation can inhibit the epileptogenesis process and help the emergence of new drugs for the treatment of epilepsy." | 1.72 | Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model. ( Akkaya, R; Filiz, AK; Karabulut, S, 2022) |
| "The overexpression of AZGP1 reduced the seizure severity, prolonged the latency of kindling, and alleviated epileptiform discharges in EEG changes induced by PTZ." | 1.48 | Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats. ( Chen, L; Ding, X; Liu, X; Liu, Y; Mo, L; Tan, X; Wang, T; Wei, X; Wen, Y; Xu, T; Yin, M; Yu, X, 2018) |
| "Seizures are sustained neuronal hyperexcitability in brain that result in loss of consciousness and injury." | 1.48 | Activation of BDNF-TrkB signaling pathway-regulated brain inflammation in pentylenetetrazole-induced seizures in zebrafish. ( Han, L; He, Q; Ji, X; Jin, M; Liu, K; Sheng, W, 2018) |
| "RESV modified brain inflammation during epileptogenesis and found to possess nootropic activity in the kindled mice." | 1.46 | Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice. ( Agarwal, NB; Hoda, U; Parvez, S; Raisuddin, S; Vohora, D, 2017) |
| "Erythropoietin (EPO) suppresses epileptic seizures, but the mechanism is unclear." | 1.40 | Erythropoietin pretreatment suppresses seizures and prevents the increase in inflammatory mediators during pentylenetetrazole-induced generalized seizures. ( Akgün-Dar, K; Albeniz, I; Bahçekapılı, N; Kandil, A; Kapucu, A; Üzüm, G; Yağız, O, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karabulut, S | 1 |
| Filiz, AK | 1 |
| Akkaya, R | 1 |
| Hoda, U | 2 |
| Jain, S | 1 |
| Samim, M | 1 |
| Jain, GK | 1 |
| Agarwal, NB | 2 |
| Liu, Y | 1 |
| Wang, T | 1 |
| Liu, X | 1 |
| Wen, Y | 1 |
| Xu, T | 1 |
| Yu, X | 1 |
| Wei, X | 1 |
| Ding, X | 1 |
| Mo, L | 1 |
| Yin, M | 1 |
| Tan, X | 1 |
| Chen, L | 1 |
| Jin, M | 1 |
| Sheng, W | 1 |
| Han, L | 1 |
| He, Q | 1 |
| Ji, X | 1 |
| Liu, K | 1 |
| Bahçekapılı, N | 1 |
| Akgün-Dar, K | 1 |
| Albeniz, I | 1 |
| Kapucu, A | 1 |
| Kandil, A | 1 |
| Yağız, O | 1 |
| Üzüm, G | 1 |
| Vohora, D | 1 |
| Parvez, S | 1 |
| Raisuddin, S | 1 |
| VOINESCO, S | 1 |
| PETRESCO, A | 1 |
| Földi, M | 1 |
| Obál, F | 1 |
| Kahán, A | 1 |
| Wagner, A | 1 |
| Csanda, E | 1 |
| Börcsök, E | 1 |
1 trial available for pentylenetetrazole and Encephalitis
| Article | Year |
|---|---|
[Lymphogenous encephalopathy: a new clinical picture and its management].
Topics: Adult; Animals; Brain Diseases; Cerebrospinal Fluid; Cerebrovascular Circulation; Child; Clinical Tr | 1967 |
7 other studies available for pentylenetetrazole and Encephalitis
| Article | Year |
|---|---|
Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model.
Topics: Animals; Cognitive Dysfunction; Cyclooxygenase 2; Encephalitis; Epilepsy; Kindling, Neurologic; Male | 2022 |
Embelin ameliorates cognitive dysfunction and progression of kindling in pentylenetetrazol-induced kindling in mice by attenuating brain inflammation.
Topics: Animals; Benzoquinones; Cognitive Dysfunction; Encephalitis; Kindling, Neurologic; Male; Mice; Penty | 2021 |
Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats.
Topics: Adipokines; Animals; Brain Waves; Carrier Proteins; Convulsants; Cytokines; Disease Models, Animal; | 2018 |
Activation of BDNF-TrkB signaling pathway-regulated brain inflammation in pentylenetetrazole-induced seizures in zebrafish.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Encephalitis; Epilepsy; G | 2018 |
Erythropoietin pretreatment suppresses seizures and prevents the increase in inflammatory mediators during pentylenetetrazole-induced generalized seizures.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Convulsants; Cytokines; Drug Administration | 2014 |
Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antioxidants; Avoidance Learning; | 2017 |
[Anatomico-clinical aspects of certain poorly classified encephalitides and perivenous encephalitides during diseases of panencephalitic nature].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Encephalitis; Female; Humans; Labor, Obstetric; Med | 1958 |