pentylenetetrazole has been researched along with Edema-Proteinuria-Hypertension Gestosis in 2 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 5.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
| "Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical-imaging syndrome as well as a critical maternal complication." | 1.56 | Contribution of excess inflammation to a possible rat model of eclamptic reversible posterior leukoencephalopathy syndrome induced by lipopolysaccharide and pentylenetetrazol: A preliminary study. ( Chen, D; Fang, X; Liang, Y; Liu, Y; Xie, M; Zhang, W, 2020) |
| "Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 1.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, X | 1 |
| Liang, Y | 1 |
| Chen, D | 1 |
| Liu, Y | 1 |
| Xie, M | 1 |
| Zhang, W | 1 |
| Johnson, AC | 1 |
| Tremble, SM | 1 |
| Chan, SL | 1 |
| Moseley, J | 1 |
| LaMarca, B | 1 |
| Nagle, KJ | 1 |
| Cipolla, MJ | 1 |
2 other studies available for pentylenetetrazole and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Contribution of excess inflammation to a possible rat model of eclamptic reversible posterior leukoencephalopathy syndrome induced by lipopolysaccharide and pentylenetetrazol: A preliminary study.
Topics: Animals; Astrocytes; Blood Pressure; Blood-Brain Barrier; Brain; Disease Models, Animal; Eclampsia; | 2020 |
Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Convulsants; Diet, High-Fat; Disease Models, Anima | 2014 |