pentylenetetrazole has been researched along with Eclampsia in 7 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Eclampsia: Onset of HYPERREFLEXIA; SEIZURES; or COMA in a previously diagnosed pre-eclamptic patient (PRE-ECLAMPSIA).
Excerpt | Relevance | Reference |
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"Our findings indicate that the administration of nicotine may attenuate microglial activity and increase eclampsia-like seizure threshold in rat hippocampus through the α7 nicotinic receptor." | 7.83 | Nicotine increases eclampsia-like seizure threshold and attenuates microglial activity in rat hippocampus through the α7 nicotinic acetylcholine receptor. ( Bao, J; Han, X; Li, X; Liu, H; Liu, Y; Thakur, M; Ye, A, 2016) |
"Eclampsia is characterized by high morbidity and mortality wordwide." | 5.51 | Magnesium sulfate attenuates brain edema by lowering AQP4 expression and inhibits glia-mediated neuroinflammation in a rodent model of eclampsia. ( Li, X; Liu, H; Yang, Y, 2019) |
"Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 5.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
"Our findings indicate that the administration of nicotine may attenuate microglial activity and increase eclampsia-like seizure threshold in rat hippocampus through the α7 nicotinic receptor." | 3.83 | Nicotine increases eclampsia-like seizure threshold and attenuates microglial activity in rat hippocampus through the α7 nicotinic acetylcholine receptor. ( Bao, J; Han, X; Li, X; Liu, H; Liu, Y; Thakur, M; Ye, A, 2016) |
"Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical-imaging syndrome as well as a critical maternal complication." | 1.56 | Contribution of excess inflammation to a possible rat model of eclamptic reversible posterior leukoencephalopathy syndrome induced by lipopolysaccharide and pentylenetetrazol: A preliminary study. ( Chen, D; Fang, X; Liang, Y; Liu, Y; Xie, M; Zhang, W, 2020) |
"Eclampsia is characterized by high morbidity and mortality wordwide." | 1.51 | Magnesium sulfate attenuates brain edema by lowering AQP4 expression and inhibits glia-mediated neuroinflammation in a rodent model of eclampsia. ( Li, X; Liu, H; Yang, Y, 2019) |
"Eclampsia is a poorly understood but potentially fatal complication of pregnancy." | 1.40 | Decreased seizure threshold in an eclampsia-like model induced in pregnant rats with lipopolysaccharide and pentylenetetrazol treatments. ( Brennecke, SP; Di, X; Hu, B; Huang, Q; Liu, H; Liu, L, 2014) |
"Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 1.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (28.57) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (57.14) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
Authors | Studies |
---|---|
Fang, X | 1 |
Liang, Y | 1 |
Chen, D | 1 |
Liu, Y | 2 |
Xie, M | 1 |
Zhang, W | 1 |
Li, X | 2 |
Liu, H | 3 |
Yang, Y | 1 |
Huang, Q | 1 |
Liu, L | 1 |
Hu, B | 1 |
Di, X | 1 |
Brennecke, SP | 1 |
Johnson, AC | 1 |
Tremble, SM | 1 |
Chan, SL | 1 |
Moseley, J | 1 |
LaMarca, B | 1 |
Nagle, KJ | 1 |
Cipolla, MJ | 1 |
Han, X | 1 |
Bao, J | 1 |
Ye, A | 1 |
Thakur, M | 1 |
GEISER-RAUCH, D | 1 |
Browne, TR | 1 |
Penry, JK | 1 |
1 review available for pentylenetetrazole and Eclampsia
Article | Year |
---|---|
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Elec | 1973 |
6 other studies available for pentylenetetrazole and Eclampsia
Article | Year |
---|---|
Contribution of excess inflammation to a possible rat model of eclamptic reversible posterior leukoencephalopathy syndrome induced by lipopolysaccharide and pentylenetetrazol: A preliminary study.
Topics: Animals; Astrocytes; Blood Pressure; Blood-Brain Barrier; Brain; Disease Models, Animal; Eclampsia; | 2020 |
Magnesium sulfate attenuates brain edema by lowering AQP4 expression and inhibits glia-mediated neuroinflammation in a rodent model of eclampsia.
Topics: Animals; Aquaporin 4; Astrocytes; Brain Edema; CA3 Region, Hippocampal; Cytokines; Disease Models, A | 2019 |
Decreased seizure threshold in an eclampsia-like model induced in pregnant rats with lipopolysaccharide and pentylenetetrazol treatments.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Eclampsia; Female; Humans; Lipopolysaccharides; Ma | 2014 |
Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Convulsants; Diet, High-Fat; Disease Models, Anima | 2014 |
Nicotine increases eclampsia-like seizure threshold and attenuates microglial activity in rat hippocampus through the α7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Blood Pressure; CA1 Region, Hippocampa | 2016 |
[Cardiazol-activated EEG in former eclampsia patients].
Topics: Eclampsia; Electroencephalography; Female; Humans; Pentylenetetrazole; Pregnancy | 1958 |