pentylenetetrazole has been researched along with Dysentery, Shiga bacillus in 3 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neurologic manifestations, mainly convulsions, are the most frequent extraintestinal complications of shigellosis." | 5.30 | Involvement of tumor necrosis factor alpha and interleukin-1beta in enhancement of pentylenetetrazole-induced seizures caused by Shigella dysenteriae. ( Ashkenazi, S; Kaminsky, E; Shulman, L; Vanichkin, A; Weizman, A; Yuhas, Y, 1999) |
| "The mean convulsion scores were 0." | 5.30 | Role of nitric oxide in the enhancement of pentylenetetrazole-induced seizures caused by Shigella dysenteriae. ( Ashkenazi, S; Balter-Seri, J; Kaminsky, E; Nofech-Mozes, Y; Weizman, A; Yuhas, Y, 1999) |
| "We have previously demonstrated that pretreatment of mice with Shigella dysenteriae sonicate enhanced their susceptibility to pentylenetetrazole-induced seizures and that tumor necrosis factor alpha (TNF-alpha) was proconvulsive in this respect." | 3.72 | Bidirectional concentration-dependent effects of tumor necrosis factor alpha in Shigella dysenteriae-related seizures. ( Ashkenazi, S; Weizman, A; Yuhas, Y, 2003) |
| "Neurologic manifestations, mainly convulsions, are the most frequent extraintestinal complications of shigellosis." | 1.30 | Involvement of tumor necrosis factor alpha and interleukin-1beta in enhancement of pentylenetetrazole-induced seizures caused by Shigella dysenteriae. ( Ashkenazi, S; Kaminsky, E; Shulman, L; Vanichkin, A; Weizman, A; Yuhas, Y, 1999) |
| "The mean convulsion scores were 0." | 1.30 | Role of nitric oxide in the enhancement of pentylenetetrazole-induced seizures caused by Shigella dysenteriae. ( Ashkenazi, S; Balter-Seri, J; Kaminsky, E; Nofech-Mozes, Y; Weizman, A; Yuhas, Y, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuhas, Y | 3 |
| Weizman, A | 3 |
| Ashkenazi, S | 3 |
| Shulman, L | 1 |
| Kaminsky, E | 2 |
| Vanichkin, A | 1 |
| Balter-Seri, J | 1 |
| Nofech-Mozes, Y | 1 |
3 other studies available for pentylenetetrazole and Dysentery, Shiga bacillus
| Article | Year |
|---|---|
Bidirectional concentration-dependent effects of tumor necrosis factor alpha in Shigella dysenteriae-related seizures.
Topics: Animals; Dose-Response Relationship, Immunologic; Dysentery, Bacillary; Mice; Mice, Inbred ICR; Pent | 2003 |
Involvement of tumor necrosis factor alpha and interleukin-1beta in enhancement of pentylenetetrazole-induced seizures caused by Shigella dysenteriae.
Topics: Animals; Blood-Brain Barrier; Dysentery, Bacillary; Interleukin-1; Male; Mice; Mice, Inbred ICR; Pen | 1999 |
Role of nitric oxide in the enhancement of pentylenetetrazole-induced seizures caused by Shigella dysenteriae.
Topics: Animals; Convulsants; Dysentery, Bacillary; Enzyme Inhibitors; Male; Mice; Mice, Inbred ICR; Nitric | 1999 |