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pentylenetetrazole and Drug Overdose

pentylenetetrazole has been researched along with Drug Overdose in 5 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"The effects of 3,5,3'-triiodothyronine (T3) levels on threshold, latency and duration of pentylenetetrazole-induced seizures were tested in rats treated with thyroxine (300 micrograms/kg."3.69T3 deficiency prolongs convulsions induced by acute pentylenetetrazole. ( Chambert, G; Pacheco-Rosado, J; Quevedo-Corona, L; Zamudio-Hernández, SR, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WHITEHEAD, RW1
ROTH, LW1
DRAPER, WB1
HARGROVE, EA1
FORD, FR1
FAZEKAS, JF2
GOLDBAUM, LR2
KOPPANYI, T2
SHEA, J1
SHEA, JG1
Pacheco-Rosado, J1
Quevedo-Corona, L1
Zamudio-Hernández, SR1
Chambert, G1

Other Studies

5 other studies available for pentylenetetrazole and Drug Overdose

ArticleYear
Antidotal action of metrazol against pentothal sodium overdose.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Barbital; Barbiturates; Drug Overdose; Pentylenetetrazole; Sodium; Thiopental

1946
Acute and chronic barbiturate intoxication recent advances in therapeutic management.
    California medicine, 1952, Volume: 77, Issue:6

    Topics: Barbiturates; Combined Modality Therapy; Conduct Disorder; Death; Disease Management; Drug Overdose;

1952
Study on the effect of overdoses of pentylenetetrazol and pentobarbital sodium combinations in human subjects.
    The Medical annals of the District of Columbia, 1954, Volume: 23, Issue:3

    Topics: Barbiturates; Drug Overdose; Humans; Pentobarbital; Pentylenetetrazole

1954
Study of the effect of overdoses of pentylenetetrazol and barbiturate combinations in human volunteers.
    The American journal of the medical sciences, 1956, Volume: 231, Issue:5

    Topics: Barbiturates; Drug Overdose; Healthy Volunteers; Humans; Pentylenetetrazole

1956
T3 deficiency prolongs convulsions induced by acute pentylenetetrazole.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1997, Volume: 29, Issue:11

    Topics: Animals; Antithyroid Agents; Colon; Convulsants; Drug Overdose; Male; Methimazole; Pentylenetetrazol

1997