pentylenetetrazole has been researched along with Diathesis in 80 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we assessed the susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice with genetically altered uric acid levels by targeting urate oxidase, which is the enzyme responsible for uric acid breakdown." | 7.83 | Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice. ( Boon, P; Carrette, E; Delbeke, J; Glorieux, G; Larsen, LE; Portelli, J; Raedt, R; Sprengers, M; Thyrion, L; Van Lysebettens, W; Vonck, K, 2016) |
| " We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target." | 7.78 | Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. ( Fitzgerald, EF; Huganir, RL; Hunganir, RL; Jensen, FE; Klein, PM; Rakhade, SN; Sun, H; Zhou, C, 2012) |
| " In the present study, we induced lithium and pilocarpine status epilepticus (SE) in 10-day-old (P10) rats." | 7.71 | Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures. ( Dubé, C; Koning, E; Nehlig, A, 2002) |
| "5 g/l in drinking water) on bicuculline- and pentylenetetrazol (PTZ)-induced seizures and c-fos expression were studied in mice." | 7.69 | Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding. ( Fredholm, BB; Georgiev, V; Johansson, B; Kuosmanen, T, 1996) |
| "Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 5.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
| "Occurrence of seizures following long-term oral administration of caffeine (0." | 5.35 | Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine. ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2008) |
| "Three flurothyl convulsions decreased the afterdischarge threshold of the amygdala and enhanced the rate of development of electrical kindling without affecting the intensity of postictal refractoriness." | 5.27 | Unidirectional interaction between flurothyl seizures and amygdala kindling. ( Albala, BJ; Moshé, SL; Okada, R; Ono, K, 1985) |
| " 24h later, animals were subjected to seizures by using either maximal electro shock or pentylenetetrazole." | 3.85 | Increase in seizure susceptibility in sepsis like condition explained by spiking cytokines and altered adhesion molecules level with impaired blood brain barrier integrity in experimental model of rats treated with lipopolysaccharides. ( Chakrabarti, A; Medhi, B; Modi, M; Saikia, UN; Sewal, RK, 2017) |
| " In this study we assessed the susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice with genetically altered uric acid levels by targeting urate oxidase, which is the enzyme responsible for uric acid breakdown." | 3.83 | Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice. ( Boon, P; Carrette, E; Delbeke, J; Glorieux, G; Larsen, LE; Portelli, J; Raedt, R; Sprengers, M; Thyrion, L; Van Lysebettens, W; Vonck, K, 2016) |
| " Secondly, we determined seizure threshold for H1 and H3 receptors agonists and antagonists in mouse model of pentylenetetrazole (PTZ)-induced clonic seizures." | 3.81 | Morphine modulates the effects of histamine H1 and H3 receptors on seizure susceptibility in pentylenetetrazole-induced seizure model of mice. ( Alijanpour, S; Amini-Khoei, H; Amiri, S; Dehpour, AR; Gooshe, M; Haj-Mirzaian, A; Hassanipour, M; Mehr, SE; Rahimi-Balaei, M; Shirzadian, A, 2015) |
| " We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target." | 3.78 | Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. ( Fitzgerald, EF; Huganir, RL; Hunganir, RL; Jensen, FE; Klein, PM; Rakhade, SN; Sun, H; Zhou, C, 2012) |
| " Three tests were used: pentylenetetrazole (PTZ)-induced seizures, isolation-induced ultrasonic vocalizations, and motor performance." | 3.77 | Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats. ( Kubová, H; Mareš, P; Mikulecká, A, 2011) |
| "Our findings suggest that the induction of acute seizures with PTZ, but not with MES, in animals pretreated with pilocarpine (regardless of SE induction) might constitute an effective and valuable method to screen AEDs and to study mechanisms involved in pharmacoresistant temporal lobe epilepsy (TLE)." | 3.75 | Assessment of seizure susceptibility in pilocarpine epileptic and nonepileptic Wistar rats and of seizure reinduction with pentylenetetrazole and electroshock models. ( Albuquerque, C; Blanco, MM; Cavarsan, CF; dos Santos, JG; Hummel, M; Kohek, SR; Mello, LE; Perez-Mendes, P, 2009) |
| "In WT mice, morphine dose-dependently decreased the thresholds of both myoclonic jerks and clonus convulsion." | 3.74 | [Involvement of endogenous histamine in modulatory effect of morphine on seizure susceptibility in mice]. ( Chen, Z; Jin, CL; Wu, DC; Zhu, YY; Zhu-Ge, ZB, 2007) |
| " The threshold to generalized clonic seizures induced by timed intravenous infusion of pentylenetetrazole (PTZ) was used as an index of seizure propensity." | 3.74 | Seizure susceptibility alteration following reversible cholestasis in mice: Modulation by opioids and nitric oxide. ( Dehpour, AR; Doratotaj, B; Gholipour, T; Honar, H; Jannati, A; Nik, HH; Noorian, AR; Riazi, K; Shariftabrizi, A, 2008) |
| "The threshold for the clonic seizures (CST) induced by acute intravenous administration of gamma-aminobutyric acid (GABA)-antagonist pentylenetetrazole (PTZ) was assessed in male and female mice." | 3.72 | Sex and estrus cycle differences in the modulatory effects of morphine on seizure susceptibility in mice. ( Dehghani, M; Dehpour, AR; Gaskari, SA; Homayoun, H; Honar, H; Rashidi, N; Riazi, K; Sadeghipour, H, 2004) |
| " In the present study, we induced lithium and pilocarpine status epilepticus (SE) in 10-day-old (P10) rats." | 3.71 | Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures. ( Dubé, C; Koning, E; Nehlig, A, 2002) |
| "The involvement of endogenous opioids and nitric oxide (NO) in the anticonvulsant effects of stress against pentylenetetrazole (PTZ)- or electroconvulsive shock-induced seizures was assessed in mice." | 3.71 | The involvement of endogenous opioids and nitricoxidergic pathway in the anticonvulsant effects of foot-shock stress in mice. ( Dehpour, AR; Homayoun, H; Khavandgar, S, 2002) |
| "Perimenstrual catamenial epilepsy, the increase in seizure frequency that some women with epilepsy experience near the time of menstruation, may in part be related to withdrawal of the progesterone metabolite allopregnanolone, an endogenous anticonvulsant neurosteroid that is a potent positive allosteric gamma-aminobutyric acidA (GABA(A)) receptor modulator." | 3.71 | Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. ( Kim, HY; Reddy, DS; Rogawski, MA, 2001) |
| " Finally, a delayed development of pentylenetetrazole-induced seizures (creating a high-energy demand) was observed in B-CK-/- mice." | 3.71 | Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility. ( Cools, AR; Fransen, J; Heerschap, A; In 't Zandt, HJ; Jost, CR; Oerlemans, F; Streijger, F; Van Der Zee, CE; Verheij, M; Wieringa, B, 2002) |
| "5 g/l in drinking water) on bicuculline- and pentylenetetrazol (PTZ)-induced seizures and c-fos expression were studied in mice." | 3.69 | Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding. ( Fredholm, BB; Georgiev, V; Johansson, B; Kuosmanen, T, 1996) |
| "We measured the release of neuropeptide Y (NPY) from hippocampal slices of rats at various times after limbic seizures induced by a subcutaneous injection of 12 mg/kg kainic acid (KA)." | 3.69 | Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats. ( Civenni, G; Messali, S; Monno, A; Rizzi, M; Samanin, R; Vezzani, A, 1994) |
| " In flurothyl-induced seizures, CA deficient mice displayed longer latencies to the onset of both clonic and tonic-clonic seizures." | 3.68 | Reduced susceptibility to seizures in carbonic anhydrase II deficient mutant mice. ( Cammer, W; Moshé, SL; Velísek, L; Xu, SG, 1993) |
| "Epilepsy is a chronic brain disease affecting millions of people worldwide." | 1.62 | Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy. ( Mosaferi, B; Najdi, N; Salari, AA; Zeraati, M, 2021) |
| "Here, we investigated the seizure susceptibility and the role of NRG1-ErbB4 signaling in PV interneurons in the suppression of epileptic seizures for rats subject to early life hypoxia." | 1.56 | Increased Seizure Susceptibility for Rats Subject to Early Life Hypoxia Might Be Associated with Brain Dysfunction of NRG1-ErbB4 Signaling in Parvalbumin Interneurons. ( Ding, W; Fan, F; Fang, Y; Hu, L; Lei, B; Liang, D; Zhang, M, 2020) |
| "In the pentylenetetrazol (PTZ) seizure-susceptibility test, dKO mice had a shorter latency to the first epileptiform spike (p = 0." | 1.51 | Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility. ( Bolkvadze, T; Ekolle Ndode-Ekane, X; Koivisto, H; Kyyriäinen, J; Lipponen, A; Pérez, LO; Pitkänen, A; Tanila, H, 2019) |
| "Alzheimer's disease is a common age associated neurodegenerative disorder associated with an elevated risk of seizures that may be fundamentally connected to cognitive dysfunction." | 1.46 | Seizure susceptibility in the APP/PS1 mouse model of Alzheimer's disease and relationship with amyloid β plaques. ( Nuñez, A; Reyes-Marin, KE, 2017) |
| "Epilepsy or seizure disorder is among the least understood chronic medical conditions affecting over 65 million people worldwide." | 1.43 | Disruption of polycystin-L causes hippocampal and thalamocortical hyperexcitability. ( Basora, N; Contreras, D; Du, Y; Harvey, M; Luo, C; Schreiber, TH; Su, X; Wu, M; Yao, G; Zhou, J, 2016) |
| "We have reported significantly higher convulsion prevalence in patients treated with cefepime than in those treated with meropenem." | 1.40 | Convulsive liability of cefepime and meropenem in normal and corneal kindled mice. ( Araki, H; Suemaru, K; Takechi, K; Tanaka, A; Tanaka, M; Watanabe, S, 2014) |
| "Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 1.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
| "We examined the seizure susceptibility of these mice to determine if the presence (BXD29-Trl4(lps-2J)/J) or absence (C57BL/10J) of p-ACC, in strains with MCD, confers a differential response to chemi-convulsive treatment." | 1.39 | Differential seizure response in two models of cortical heterotopia. ( Gabel, LA; Ibanez, N; Manglani, M; Ramos, RL; Roberts, J; Rosen, GD, 2013) |
| " Thus we aim to evaluate the effect of an increase in Cstb gene dosage on spontaneous epileptic activity and susceptibility to PTZ-induced seizure." | 1.37 | Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB. ( Bizot, JC; Brault, V; Costet, N; Hérault, Y; Martin, B, 2011) |
| "There is some evidence that epileptic seizures could be induced or increased by 5-hydroxytryptamine (5-HT) attenuation, while augmentation of serotonin functions within the brain (e." | 1.36 | Seizure susceptibility alteration through 5-HT(3) receptor: modulation by nitric oxide. ( Dehpour, AR; Ghaffarpour, M; Ghasemi, M; Gholipour, T; Riazi, K, 2010) |
| " However, in both groups chronic administration of melatonin (20mg/kg) reversed the effect of LD cycle alteration on CST." | 1.35 | Effect of acute and chronic photoperiod modulation on pentylenetetrazole-induced clonic seizure threshold in mice. ( Dehpour, AR; Ghahremani, MH; Riazi, K; Tahsili-Fahadan, P; Yahyavi-Firouz-Abadi, N, 2008) |
| "Occurrence of seizures following long-term oral administration of caffeine (0." | 1.35 | Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine. ( Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM, 2008) |
| "Potentiation of convulsions by BSO treatment was recovered by supplying GSH (10 nmol, i." | 1.31 | The possible role of endogenous glutathione as an anticonvulsant in mice. ( Abe, K; Nakanishi, K; Saito, H, 2000) |
| "Susceptibility to PTZ-induced convulsive seizures was significantly higher in -/- versus +/+ mice." | 1.31 | Behavior and physiology of mice lacking the GABAA-receptor delta subunit. ( Banerjee, PK; Homanics, GE; Li, Z; Mihalek, RM; Olsen, RW; Spigelman, I, 2002) |
| "Stress affects seizure susceptibility in animals and humans, but the underlying mechanisms are obscure." | 1.31 | Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. ( Reddy, DS; Rogawski, MA, 2002) |
| "Infantile spasms are generalized convulsive seizures seen in the first year of life." | 1.31 | The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats. ( Burnham, WM; Edwards, HE; Vimal, S, 2002) |
| " We demonstrate that jerky has a dosage-sensitive function (haploinsufficiency) in brain and that this sensitivity to reduced jerky dosage could explain the occurrence of seizures in hemizygotes." | 1.30 | Sensitivity to jerky gene dosage underlies epileptic seizures in mice. ( Donovan, GP; Gal, J; Gudas, LJ; Harden, C; Ho, L; Sibille, E; Toth, M; Trifiletti, R, 1997) |
| "Results indicate that seizure threshold was significantly elevated with increasing ketogenic ratios (i." | 1.30 | Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat. ( Bough, KJ; Chen, RS; Eagles, DA, 1999) |
| "Pregnenolone sulfate (PS) is an endogenous neurosteroid known to antagonize GABA(A) receptor-mediated inhibitory responses and potentiate NMDA receptor-mediated excitatory responses in vitro." | 1.30 | Convulsant actions of the neurosteroid pregnenolone sulfate in mice. ( Juhng, KN; Kirkby, RD; Kokate, TG; Llamas, J; Rogawski, MA; Yamaguchi, S, 1999) |
| "glucocorticoids on convulsions." | 1.29 | Type I corticosteroid receptors modulate PTZ-induced convulsions of withdrawal seizure prone mice. ( Crabbe, JC; Keith, LD; Roberts, AJ, 1993) |
| "Convulsions were induced by heat or pentylenetetrazol on days 1, 10 or 21." | 1.29 | The effects of a single neonatally induced convulsion on spatial navigation, locomotor activity and convulsion susceptibility in the adult rat. ( Boon, F; Cain, DP; Kornelsen, RA; Leung, LS, 1996) |
| "Increased susceptibility to seizures in the deficient animals was observed as increased severity of the seizures, decreased threshold for the dose of the chemostimulant and time to seizure, or a combination thereof." | 1.29 | Indispensable amino acid deficiency and increased seizure susceptibility in rats. ( Barrett, JA; Dixon, KD; Gietzen, DW; Jones, AC; Truong, BG; Washburn, DS, 1996) |
| "Other convulsion types, e." | 1.29 | Mineralocorticoid receptors mediate the enhancing effects of corticosterone on convulsion susceptibility in mice. ( Keith, LD; Roberts, AJ, 1994) |
| "In addition, ED and latency to convulsion were measured in WSP and WSR mice at 5 different concentrations of PTZ." | 1.28 | Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice. ( Crabbe, JC; Cross, SJ; Kosobud, AE, 1992) |
| "Convulsions were caused by intraabdominal injections of corazol." | 1.28 | [Correlations of convulsive and hypoxic resistance in rats at different stages of ontogenesis]. ( Agadzhanian, NA; Starykh, EV; Torshin, VI, 1991) |
| "Three flurothyl convulsions decreased the afterdischarge threshold of the amygdala and enhanced the rate of development of electrical kindling without affecting the intensity of postictal refractoriness." | 1.27 | Unidirectional interaction between flurothyl seizures and amygdala kindling. ( Albala, BJ; Moshé, SL; Okada, R; Ono, K, 1985) |
| "Convulsions were induced in young rats (1-21 days) with pentylenetetrazol or hyperthermia." | 1.27 | A single neonatal pentylenetetrazol or hyperthermia convulsion increases kindling susceptibility in the adult rat. ( Cain, DP; Gilbert, ME, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (13.75) | 18.7374 |
| 1990's | 17 (21.25) | 18.2507 |
| 2000's | 23 (28.75) | 29.6817 |
| 2010's | 24 (30.00) | 24.3611 |
| 2020's | 5 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Villalpando-Vargas, F | 1 |
| Medina-Ceja, L | 1 |
| Santerre, A | 1 |
| Enciso-Madero, EA | 1 |
| Nesci, V | 1 |
| Russo, E | 1 |
| Arcidiacono, B | 1 |
| Citraro, R | 1 |
| Tallarico, M | 1 |
| Constanti, A | 1 |
| Brunetti, A | 1 |
| De Sarro, G | 1 |
| Leo, A | 1 |
| Liang, D | 1 |
| Fan, F | 1 |
| Ding, W | 1 |
| Fang, Y | 1 |
| Hu, L | 1 |
| Lei, B | 1 |
| Zhang, M | 1 |
| Sinha, P | 1 |
| Verma, B | 1 |
| Ganesh, S | 1 |
| Zeraati, M | 1 |
| Najdi, N | 1 |
| Mosaferi, B | 1 |
| Salari, AA | 1 |
| Díaz-Alonso, J | 1 |
| de Salas-Quiroga, A | 1 |
| Paraíso-Luna, J | 1 |
| García-Rincón, D | 1 |
| Garcez, PP | 1 |
| Parsons, M | 1 |
| Andradas, C | 1 |
| Sánchez, C | 1 |
| Guillemot, F | 1 |
| Guzmán, M | 1 |
| Galve-Roperh, I | 1 |
| Sewal, RK | 1 |
| Modi, M | 1 |
| Saikia, UN | 1 |
| Chakrabarti, A | 1 |
| Medhi, B | 1 |
| Reyes-Marin, KE | 1 |
| Nuñez, A | 1 |
| Kyyriäinen, J | 1 |
| Bolkvadze, T | 1 |
| Koivisto, H | 1 |
| Lipponen, A | 1 |
| Pérez, LO | 1 |
| Ekolle Ndode-Ekane, X | 1 |
| Tanila, H | 1 |
| Pitkänen, A | 2 |
| Chmielewska, N | 1 |
| Maciejak, P | 1 |
| Turzyńska, D | 1 |
| Sobolewska, A | 1 |
| Wisłowska-Stanek, A | 1 |
| Kołosowska, K | 1 |
| Płaźnik, A | 1 |
| Szyndler, J | 1 |
| Aksoy, D | 1 |
| Solmaz, V | 1 |
| Taşkıran, D | 1 |
| Erbaş, O | 1 |
| Tanaka, A | 2 |
| Takechi, K | 1 |
| Watanabe, S | 1 |
| Tanaka, M | 1 |
| Suemaru, K | 1 |
| Araki, H | 1 |
| Dai, YJ | 1 |
| Xu, ZH | 1 |
| Feng, B | 1 |
| Xu, CL | 1 |
| Zhao, HW | 1 |
| Wu, DC | 2 |
| Hu, WW | 1 |
| Chen, Z | 3 |
| Johnson, AC | 1 |
| Tremble, SM | 1 |
| Chan, SL | 1 |
| Moseley, J | 1 |
| LaMarca, B | 1 |
| Nagle, KJ | 1 |
| Cipolla, MJ | 1 |
| Amini-Khoei, H | 1 |
| Rahimi-Balaei, M | 1 |
| Amiri, S | 1 |
| Haj-Mirzaian, A | 1 |
| Hassanipour, M | 1 |
| Shirzadian, A | 1 |
| Gooshe, M | 1 |
| Alijanpour, S | 1 |
| Mehr, SE | 1 |
| Dehpour, AR | 6 |
| Yao, G | 1 |
| Luo, C | 1 |
| Harvey, M | 1 |
| Wu, M | 1 |
| Schreiber, TH | 1 |
| Du, Y | 1 |
| Basora, N | 1 |
| Su, X | 1 |
| Contreras, D | 1 |
| Zhou, J | 1 |
| Thyrion, L | 1 |
| Portelli, J | 1 |
| Raedt, R | 1 |
| Glorieux, G | 1 |
| Larsen, LE | 1 |
| Sprengers, M | 1 |
| Van Lysebettens, W | 1 |
| Carrette, E | 1 |
| Delbeke, J | 1 |
| Vonck, K | 1 |
| Boon, P | 1 |
| Grauncke, AC | 1 |
| Souza, TL | 1 |
| Ribeiro, LR | 1 |
| Brant, F | 1 |
| Machado, FS | 1 |
| Oliveira, MS | 1 |
| Shen, Y | 1 |
| Qin, H | 1 |
| Chen, J | 1 |
| Mou, L | 1 |
| He, Y | 1 |
| Yan, Y | 1 |
| Zhou, H | 1 |
| Lv, Y | 1 |
| Wang, J | 1 |
| Zhou, YD | 1 |
| Qin, R | 1 |
| Cao, S | 1 |
| Lyu, T | 1 |
| Qi, C | 1 |
| Zhang, W | 1 |
| Wang, Y | 1 |
| Tahsili-Fahadan, P | 1 |
| Yahyavi-Firouz-Abadi, N | 1 |
| Riazi, K | 4 |
| Ghahremani, MH | 1 |
| Blanco, MM | 1 |
| dos Santos, JG | 1 |
| Perez-Mendes, P | 1 |
| Kohek, SR | 1 |
| Cavarsan, CF | 1 |
| Hummel, M | 1 |
| Albuquerque, C | 1 |
| Mello, LE | 1 |
| Bae, MH | 1 |
| Bissonette, GB | 1 |
| Mars, WM | 1 |
| Michalopoulos, GK | 1 |
| Achim, CL | 1 |
| Depireux, DA | 1 |
| Powell, EM | 1 |
| Gholipour, T | 2 |
| Ghasemi, M | 1 |
| Ghaffarpour, M | 1 |
| Uzüm, G | 1 |
| Akgün-Dar, K | 1 |
| Aksu, U | 1 |
| Mikulecká, A | 1 |
| Mareš, P | 2 |
| Kubová, H | 2 |
| Brault, V | 1 |
| Martin, B | 1 |
| Costet, N | 1 |
| Bizot, JC | 1 |
| Hérault, Y | 1 |
| Harai, T | 1 |
| Inoue, R | 1 |
| Fujita, Y | 1 |
| Horio, M | 1 |
| Hashimoto, K | 1 |
| Hongou, K | 1 |
| Miyawaki, T | 1 |
| Mori, H | 1 |
| Buga, AM | 1 |
| Vintilescu, R | 1 |
| Balseanu, AT | 1 |
| Pop, OT | 1 |
| Streba, C | 1 |
| Toescu, E | 1 |
| Popa-Wagner, A | 2 |
| Gabel, LA | 1 |
| Manglani, M | 1 |
| Ibanez, N | 1 |
| Roberts, J | 1 |
| Ramos, RL | 1 |
| Rosen, GD | 1 |
| Rakhade, SN | 1 |
| Fitzgerald, EF | 1 |
| Klein, PM | 1 |
| Zhou, C | 1 |
| Sun, H | 1 |
| Huganir, RL | 1 |
| Hunganir, RL | 1 |
| Jensen, FE | 1 |
| Spigelman, I | 1 |
| Li, Z | 1 |
| Banerjee, PK | 1 |
| Mihalek, RM | 1 |
| Homanics, GE | 1 |
| Olsen, RW | 1 |
| Nehlig, A | 1 |
| Dubé, C | 1 |
| Koning, E | 1 |
| Schmoll, H | 1 |
| Badan, I | 1 |
| Grecksch, G | 1 |
| Walker, L | 1 |
| Kessler, C | 1 |
| SVORAD, D | 2 |
| ONUMA, T | 1 |
| DOLINA, SA | 1 |
| SWINYARD, EA | 1 |
| SCHIFFMAN, DO | 1 |
| GOODMAN, LS | 1 |
| Wu, HM | 1 |
| Liang, YC | 1 |
| Chen, SH | 2 |
| Huang, CC | 1 |
| Tsai, JJ | 1 |
| Hsieh, CL | 1 |
| Hsu, KS | 1 |
| Honar, H | 2 |
| Homayoun, H | 2 |
| Rashidi, N | 1 |
| Dehghani, M | 1 |
| Sadeghipour, H | 1 |
| Gaskari, SA | 1 |
| Chen, WF | 1 |
| Chang, H | 1 |
| Huang, LT | 1 |
| Lai, MC | 1 |
| Yang, CH | 1 |
| Wan, TH | 1 |
| Yang, SN | 1 |
| Locke, CJ | 1 |
| Williams, SN | 1 |
| Schwarz, EM | 1 |
| Caldwell, GA | 1 |
| Caldwell, KA | 1 |
| Tchekalarova, J | 2 |
| Zhu-Ge, ZB | 1 |
| Zhu, YY | 1 |
| Jin, CL | 1 |
| Kharatishvili, I | 1 |
| Immonen, R | 1 |
| Gröhn, O | 1 |
| Noorian, AR | 1 |
| Jannati, A | 1 |
| Doratotaj, B | 1 |
| Nik, HH | 1 |
| Shariftabrizi, A | 1 |
| El Yacoubi, M | 1 |
| Ledent, C | 1 |
| Parmentier, M | 1 |
| Costentin, J | 1 |
| Vaugeois, JM | 1 |
| Holmes, GL | 2 |
| Albala, BJ | 2 |
| Moshé, SL | 3 |
| McCaughran, JA | 1 |
| Manetto, C | 1 |
| Vezzani, A | 1 |
| Civenni, G | 1 |
| Rizzi, M | 1 |
| Monno, A | 1 |
| Messali, S | 1 |
| Samanin, R | 1 |
| Roberts, AJ | 2 |
| Keith, LD | 2 |
| Crabbe, JC | 2 |
| Velísek, L | 1 |
| Xu, SG | 1 |
| Cammer, W | 1 |
| Kornelsen, RA | 1 |
| Boon, F | 1 |
| Leung, LS | 1 |
| Cain, DP | 2 |
| Gietzen, DW | 1 |
| Dixon, KD | 1 |
| Truong, BG | 1 |
| Jones, AC | 1 |
| Barrett, JA | 1 |
| Washburn, DS | 1 |
| Sircar, R | 1 |
| Johansson, B | 1 |
| Georgiev, V | 2 |
| Kuosmanen, T | 1 |
| Fredholm, BB | 1 |
| Madeja, M | 1 |
| Musshoff, U | 1 |
| Speckmann, EJ | 1 |
| Donovan, GP | 1 |
| Harden, C | 1 |
| Gal, J | 1 |
| Ho, L | 1 |
| Sibille, E | 1 |
| Trifiletti, R | 1 |
| Gudas, LJ | 1 |
| Toth, M | 1 |
| Snyder-Keller, A | 1 |
| Keller, RW | 1 |
| Kokate, TG | 1 |
| Juhng, KN | 1 |
| Kirkby, RD | 1 |
| Llamas, J | 1 |
| Yamaguchi, S | 1 |
| Rogawski, MA | 3 |
| Bough, KJ | 1 |
| Chen, RS | 1 |
| Eagles, DA | 1 |
| Abe, K | 1 |
| Nakanishi, K | 1 |
| Saito, H | 1 |
| Silveira, DC | 1 |
| Schachter, SC | 1 |
| Geula, C | 1 |
| Schomer, DL | 1 |
| Reddy, DS | 2 |
| Kim, HY | 1 |
| Golarai, G | 1 |
| Greenwood, AC | 1 |
| Feeney, DM | 1 |
| Connor, JA | 1 |
| Kambourova, T | 1 |
| Edwards, HE | 1 |
| Vimal, S | 1 |
| Burnham, WM | 1 |
| Khavandgar, S | 1 |
| Jost, CR | 1 |
| Van Der Zee, CE | 1 |
| In 't Zandt, HJ | 1 |
| Oerlemans, F | 1 |
| Verheij, M | 1 |
| Streijger, F | 1 |
| Fransen, J | 1 |
| Heerschap, A | 1 |
| Cools, AR | 1 |
| Wieringa, B | 1 |
| Chiba, S | 1 |
| Muneoka, Y | 1 |
| Sato, Y | 1 |
| Miyagishi, T | 1 |
| Kosobud, AE | 1 |
| Cross, SJ | 1 |
| Giorgi, O | 1 |
| Orlandi, M | 1 |
| Geic, M | 1 |
| Corda, MG | 1 |
| Agadzhanian, NA | 1 |
| Torshin, VI | 1 |
| Starykh, EV | 1 |
| Schmidt, J | 1 |
| Okada, R | 1 |
| Ono, K | 1 |
| Gilbert, ME | 1 |
| Hunt, WA | 1 |
80 other studies available for pentylenetetrazole and Diathesis
| Article | Year |
|---|---|
The anticonvulsant effect of sparteine on pentylenetetrazole-induced seizures in rats: a behavioral, electroencephalographic, morphological and molecular study.
Topics: Animals; Anticonvulsants; Behavior, Animal; Biomarkers; Brain; Disease Management; Disease Models, A | 2020 |
Metabolic Alterations Predispose to Seizure Development in High-Fat Diet-Treated Mice: the Role of Metformin.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Blood Glucose; Body Composition; Depression; | 2020 |
Increased Seizure Susceptibility for Rats Subject to Early Life Hypoxia Might Be Associated with Brain Dysfunction of NRG1-ErbB4 Signaling in Parvalbumin Interneurons.
Topics: Animals; Animals, Newborn; Brain; Cell Count; Disease Susceptibility; Female; Gene Expression Regula | 2020 |
Trehalose Ameliorates Seizure Susceptibility in Lafora Disease Mouse Models by Suppressing Neuroinflammation and Endoplasmic Reticulum Stress.
Topics: Animals; Autophagy; Brain; Calcium-Binding Proteins; Disease Models, Animal; Disease Susceptibility; | 2021 |
Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy.
Topics: Animals; Anxiety; Behavior, Animal; Cognitive Dysfunction; Convulsants; Disease Models, Animal; Dise | 2021 |
Loss of Cannabinoid CB1 Receptors Induces Cortical Migration Malformations and Increases Seizure Susceptibility.
Topics: Animals; Cell Movement; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Electropora | 2017 |
Increase in seizure susceptibility in sepsis like condition explained by spiking cytokines and altered adhesion molecules level with impaired blood brain barrier integrity in experimental model of rats treated with lipopolysaccharides.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Cytokines; Disease Models, Animal; Disease Sus | 2017 |
Seizure susceptibility in the APP/PS1 mouse model of Alzheimer's disease and relationship with amyloid β plaques.
Topics: Alzheimer Disease; Animals; Benzylamines; Cerebral Cortex; Disease Models, Animal; Disease Susceptib | 2017 |
Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility.
Topics: Animals; Anxiety; Avoidance Learning; Brain Waves; Convulsants; Disease Models, Animal; Disease Susc | 2019 |
The role of UCH-L1, MMP-9, and GFAP as peripheral markers of different susceptibility to seizure development in a preclinical model of epilepsy.
Topics: Animals; Biomarkers; Brain Chemistry; Convulsants; Disease Susceptibility; Glial Fibrillary Acidic P | 2019 |
The association between seizure predisposition and inflammation in a rat model of fatty liver disease.
Topics: Animals; Brain; Convulsants; Disease Susceptibility; Electroencephalography; Fatty Liver; Fructose; | 2014 |
Convulsive liability of cefepime and meropenem in normal and corneal kindled mice.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Convulsants; Disease Susceptibility; Drug | 2014 |
Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures.
Topics: Animals; Convulsants; Disease Models, Animal; Disease Susceptibility; Electroshock; Female; Fever; M | 2014 |
Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Convulsants; Diet, High-Fat; Disease Models, Anima | 2014 |
Morphine modulates the effects of histamine H1 and H3 receptors on seizure susceptibility in pentylenetetrazole-induced seizure model of mice.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Histamine | 2015 |
Disruption of polycystin-L causes hippocampal and thalamocortical hyperexcitability.
Topics: Animals; Calcium Channels; Cerebral Cortex; Cilia; Cyclic AMP; Cyclic AMP Response Element-Binding P | 2016 |
Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice.
Topics: Animals; Brain; Convulsants; Disease Models, Animal; Disease Susceptibility; Mice; Mice, Inbred C57B | 2016 |
Increased susceptibility to pentylenetetrazol following survival of cerebral malaria in mice.
Topics: Animals; Body Weight; Convulsants; Disease Models, Animal; Disease Susceptibility; Electroencephalog | 2016 |
Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons.
Topics: Animals; Animals, Newborn; Astrocytes; Coculture Techniques; Dendrites; Disease Susceptibility; Enzy | 2016 |
CDYL Deficiency Disrupts Neuronal Migration and Increases Susceptibility to Epilepsy.
Topics: Actin Cytoskeleton; Actins; Animals; Brain; Cell Movement; Cell Polarity; Chromatin; Co-Repressor Pr | 2017 |
Effect of acute and chronic photoperiod modulation on pentylenetetrazole-induced clonic seizure threshold in mice.
Topics: Animals; Circadian Rhythm; Disease Susceptibility; Male; Melatonin; Mice; Pentylenetetrazole; Photop | 2008 |
Assessment of seizure susceptibility in pilocarpine epileptic and nonepileptic Wistar rats and of seizure reinduction with pentylenetetrazole and electroshock models.
Topics: Analysis of Variance; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Disease Suscept | 2009 |
Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; A | 2010 |
Seizure susceptibility alteration through 5-HT(3) receptor: modulation by nitric oxide.
Topics: Animals; Anticonvulsants; Arginine; Disease Models, Animal; Disease Susceptibility; Dose-Response Re | 2010 |
The effects of atorvastatin on memory deficit and seizure susceptibility in pentylentetrazole-kindled rats.
Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Atorvastatin; Avoidance Learning; Disease S | 2010 |
Rebound increase in seizure susceptibility but not isolation-induced calls after single administration of clonazepam and Ro 19-8022 in infant rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Clonazepam; Disease Susceptibility; GABA Modulators | 2011 |
Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.
Topics: Animals; Atrophy; Brain; Cystatin B; Disease Models, Animal; Disease Susceptibility; Down Syndrome; | 2011 |
Decreased susceptibility to seizures induced by pentylenetetrazole in serine racemase knockout mice.
Topics: Amino Acids; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Convulsants | 2012 |
Repeated PTZ treatment at 25-day intervals leads to a highly efficient accumulation of doublecortin in the dorsal hippocampus of rats.
Topics: Animals; Biomarkers; Bromodeoxyuridine; Cell Count; Cell Lineage; Disease Susceptibility; Dose-Respo | 2012 |
Differential seizure response in two models of cortical heterotopia.
Topics: Agenesis of Corpus Callosum; Animals; Cerebral Cortex; Choristoma; Convulsants; Disease Models, Anim | 2013 |
Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Disks La | 2012 |
Behavior and physiology of mice lacking the GABAA-receptor delta subunit.
Topics: Animals; Behavior, Animal; Cell Membrane; Disease Susceptibility; Female; Kinetics; Male; Mice; Mice | 2002 |
Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures.
Topics: Aging; Animals; Animals, Newborn; Cerebellar Cortex; Disease Models, Animal; Disease Susceptibility; | 2002 |
Kindling status in sprague-dawley rats induced by pentylenetetrazole: involvement of a critical development period.
Topics: Animals; Biomarkers; Blotting, Northern; Disease Models, Animal; Disease Susceptibility; Epilepsy; G | 2003 |
[Susceptibility to convulsions in phylogenesis; experimental convulsions in vertebrates produced with cardiazole].
Topics: Animals; Disease Susceptibility; Pentylenetetrazole; Phylogeny; Seizures; Vertebrates | 1955 |
Paroxysmal susceptibility in the light of phylogenesis; experimental convulsions in vertebrates, elicited by cardiazol.
Topics: Animals; Disease Susceptibility; Pentylenetetrazole; Phylogeny; Seizures; Vertebrates | 1955 |
Relationships of the predisposition to convulsions with the action potentials of the autonomic nerves and the brain. II. Changes in action potential of the autonomic nerves and the brain under conditions for increasing the predisposition to convulsions.
Topics: Action Potentials; Autonomic Nervous System; Autonomic Pathways; Brain; Disease Susceptibility; Huma | 1957 |
[ON PHYSIOLOGICAL ANALYSIS OF "PREDISPOSITION TO CONVULSIONS"].
Topics: Brain; Camphor; Cerebral Cortex; Disease Susceptibility; Electrophysiological Phenomena; Electrophys | 1963 |
Effect of variations in extracellular sodium concentration on the susceptibility of mice to pentylenetetrazole (metrazol)-induced seizures.
Topics: Animals; Blood; Disease Susceptibility; Mice; Pentylenetetrazole; Seizures; Sodium | 1955 |
Valacyclovir treatment ameliorates the persistently increased pentylenetetrazol-induced seizure susceptibility in mice with herpes simplex virus type 1 infection.
Topics: Acyclovir; Animals; Antiviral Agents; Behavior, Animal; Body Weight; Disease Susceptibility; Dose-Re | 2004 |
Sex and estrus cycle differences in the modulatory effects of morphine on seizure susceptibility in mice.
Topics: Animals; Anticonvulsants; Convulsants; Disease Susceptibility; Dose-Response Relationship, Drug; Est | 2004 |
Alterations in long-term seizure susceptibility and the complex of PSD-95 with NMDA receptor from animals previously exposed to perinatal hypoxia.
Topics: Animals; Animals, Newborn; Brain; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Disease M | 2006 |
Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis ele | 2006 |
Effects of postnatal caffeine exposure on seizure susceptibility in developing rats.
Topics: Age Factors; Aminophylline; Animals; Animals, Newborn; Behavior, Animal; Bicuculline; Caffeine; Cent | 2007 |
[Involvement of endogenous histamine in modulatory effect of morphine on seizure susceptibility in mice].
Topics: Animals; Disease Susceptibility; Dose-Response Relationship, Drug; Histamine; Histidine Decarboxylas | 2007 |
Quantitative diffusion MRI of hippocampus as a surrogate marker for post-traumatic epileptogenesis.
Topics: Animals; Brain Injuries; Cerebral Cortex; Convulsants; Diffusion Magnetic Resonance Imaging; Disease | 2007 |
Seizure susceptibility alteration following reversible cholestasis in mice: Modulation by opioids and nitric oxide.
Topics: 1-Naphthylisothiocyanate; Alkaline Phosphatase; Animals; Bilirubin; Biomarkers; Cholestasis; Corn Oi | 2008 |
Evidence for the involvement of the adenosine A(2A) receptor in the lowered susceptibility to pentylenetetrazol-induced seizures produced in mice by long-term treatment with caffeine.
Topics: Analysis of Variance; Animals; Caffeine; Disease Models, Animal; Disease Susceptibility; Dose-Respon | 2008 |
Effect of a single brief seizure on subsequent seizure susceptibility in the immature rat.
Topics: Animals; Disease Susceptibility; Electroshock; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; | 1984 |
Potentiation of hyperthermia-induced convulsions in the developing rat by previous treatment with pentylenetetrazol.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Male; Pentylenetetrazole; Rats; Rats, Inbre | 1983 |
Enhanced neuropeptide Y release in the hippocampus is associated with chronic seizure susceptibility in kainic acid treated rats.
Topics: Animals; Antibodies; Chronic Disease; Disease Susceptibility; Dose-Response Relationship, Drug; Elec | 1994 |
Mineralocorticoid receptors mediate the enhancing effects of corticosterone on convulsion susceptibility in mice.
Topics: Animals; Corticosterone; Disease Susceptibility; Kainic Acid; Male; Mice; Mice, Inbred Strains; Pent | 1994 |
Type I corticosteroid receptors modulate PTZ-induced convulsions of withdrawal seizure prone mice.
Topics: Aminoglutethimide; Animals; Desoxycorticosterone; Dexamethasone; Disease Susceptibility; Ethanol; Ma | 1993 |
Reduced susceptibility to seizures in carbonic anhydrase II deficient mutant mice.
Topics: Acoustic Stimulation; Animals; Carbonic Anhydrases; Disease Susceptibility; Epilepsy, Tonic-Clonic; | 1993 |
The effects of a single neonatally induced convulsion on spatial navigation, locomotor activity and convulsion susceptibility in the adult rat.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Disease Susceptibility; Hot Temperature; Mal | 1996 |
Indispensable amino acid deficiency and increased seizure susceptibility in rats.
Topics: Amino Acids; Animals; Bicuculline; Differential Threshold; Disease Susceptibility; Drug Administrati | 1996 |
Repeated postnatal phencyclidine administration in female juvenile rat delays onset of puberty but has no effect on pentylenetetrazol-induced seizure-susceptibility.
Topics: Animals; Animals, Newborn; Disease Susceptibility; Estrus; Female; Ovulation; Pentylenetetrazole; Ph | 1995 |
Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding.
Topics: Animals; Autoradiography; Behavior, Animal; Bicuculline; Brain; Caffeine; Disease Susceptibility; Ma | 1996 |
Diversity of potassium channels contributing to differences in brain area-specific seizure susceptibility: sensitivity of different potassium channels to the epileptogenic agent pentylenetetrazol.
Topics: Animals; Brain Mapping; Cerebellum; Cerebral Cortex; Disease Susceptibility; Epilepsy; Hippocampus; | 1997 |
Sensitivity to jerky gene dosage underlies epileptic seizures in mice.
Topics: Aging; Alleles; Amino Acid Sequence; Animals; Brain; Cerebral Cortex; Disease Susceptibility; DNA Pr | 1997 |
Prenatal cocaine exposure increases susceptibility to drug-induced seizures. c-fos induction and brain cocaine levels.
Topics: Animals; Brain; Cocaine; Disease Susceptibility; Female; Gene Expression Regulation; Male; Pentylene | 1998 |
Convulsant actions of the neurosteroid pregnenolone sulfate in mice.
Topics: Animals; Convulsants; Disease Susceptibility; Drug Synergism; Injections, Intraventricular; Male; Mi | 1999 |
Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Body Weight; Convulsants; Diet; Differential Threshold; Disea | 1999 |
The possible role of endogenous glutathione as an anticonvulsant in mice.
Topics: Animals; Brain; Buthionine Sulfoximine; Convulsants; Disease Susceptibility; Drug Synergism; Glutath | 2000 |
Increased susceptibility to generalized seizures after immunolesions of the basal forebrain cholinergic neurons in rats.
Topics: Acetylcholinesterase; Animals; Convulsants; Denervation; Disease Susceptibility; Epilepsy, Generaliz | 2000 |
Neurosteroid withdrawal model of perimenstrual catamenial epilepsy.
Topics: 20-alpha-Dihydroprogesterone; Adult; Animals; Behavior, Animal; Disease Models, Animal; Disease Susc | 2001 |
Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Injuries; Cell Count; Cell Death; Chronic Disease; Denta | 2001 |
Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptors.
Topics: Adenosine; Angiotensin II; Angiotensin III; Angiotensins; Animals; Brain; Convulsants; Disease Susce | 2001 |
Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.
Topics: 5-alpha Reductase Inhibitors; Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Convu | 2002 |
The effects of ACTH and adrenocorticosteroids on seizure susceptibility in 15-day-old male rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Dehydroepiandrosterone; Desoxycor | 2002 |
The involvement of endogenous opioids and nitricoxidergic pathway in the anticonvulsant effects of foot-shock stress in mice.
Topics: Animals; Convulsants; Differential Threshold; Disease Susceptibility; Electroshock; Endorphins; Foot | 2002 |
Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility.
Topics: Animals; Behavior, Animal; Brain; Convulsants; Creatine Kinase; Creatine Kinase, BB Form; Disease Su | 2002 |
[Seizure susceptibility in aged rats--pentylenetetrazol-induced seizures and amygdaloid kindling seizures].
Topics: Aging; Amygdala; Animals; Disease Susceptibility; Kindling, Neurologic; Male; Pentylenetetrazole; Ra | 1992 |
Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice.
Topics: Animals; Body Weight; Brain; Disease Susceptibility; Dose-Response Relationship, Drug; Environment; | 1992 |
MK-801 prevents the decrease in 35S-TBPS binding in the rat cerebral cortex induced by pentylenetetrazol kindling.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convul | 1991 |
[Correlations of convulsive and hypoxic resistance in rats at different stages of ontogenesis].
Topics: Age Factors; Animals; Animals, Newborn; Atmosphere Exposure Chambers; Disease Models, Animal; Diseas | 1991 |
Lithium suppresses seizure susceptibility in pentylenetetrazol-kindled rats.
Topics: Animals; Chlorides; Disease Susceptibility; Female; Kindling, Neurologic; Lithium; Lithium Chloride; | 1986 |
Unidirectional interaction between flurothyl seizures and amygdala kindling.
Topics: Amygdala; Animals; Disease Susceptibility; Electric Stimulation; Flurothyl; Kindling, Neurologic; Ma | 1985 |
A single neonatal pentylenetetrazol or hyperthermia convulsion increases kindling susceptibility in the adult rat.
Topics: Amygdala; Animals; Animals, Newborn; Disease Susceptibility; Hippocampus; Hyperthermia, Induced; Kin | 1985 |
Changes in the neuro-excitability of alcohol-dependent rats undergoing withdrawal as measured by the pentylenetetrazole seizure threshold.
Topics: Animals; Disease Susceptibility; Ethanol; Humans; Male; Pentylenetetrazole; Proadifen; Rats; Seizure | 1973 |