pentylenetetrazole has been researched along with Depressive Disorder in 16 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated the effects of mirtazapine on pentylenetetrazole (PTZ)- and maximal electroconvulsive shock (MES)-induced seizures in mice." | 7.74 | Mirtazapine does not affect pentylenetetrazole- and maximal electroconvulsive shock-induced seizures in mice. ( Kayir, H; Sezer, Z; Uzbay, TI; Yilmaz, I, 2007) |
| "for 15 days." | 5.46 | Ferulic Acid Supplementation for Management of Depression in Epilepsy. ( Goel, RK; Kaur, T; Singh, T, 2017) |
| "Depression was evaluated in all experimental groups using the tail suspension and sucrose preference test on days 1, 5, 10 and 15, 2 h after pentylenetetrazole challenge." | 5.46 | Adjuvant quercetin therapy for combined treatment of epilepsy and comorbid depression. ( Goel, RK; Kaur, T; Singh, T, 2017) |
| "The present study aimed to develop a neurochemistry-based single or adjuvant therapy approach for comprehensive management of epilepsy and associated depression employing pentylenetetrazole-kindled animals." | 3.83 | Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression. ( Goel, RK; Singh, T, 2016) |
| " We have investigated the effects of mirtazapine on pentylenetetrazole (PTZ)- and maximal electroconvulsive shock (MES)-induced seizures in mice." | 3.74 | Mirtazapine does not affect pentylenetetrazole- and maximal electroconvulsive shock-induced seizures in mice. ( Kayir, H; Sezer, Z; Uzbay, TI; Yilmaz, I, 2007) |
| "for 15 days." | 1.46 | Ferulic Acid Supplementation for Management of Depression in Epilepsy. ( Goel, RK; Kaur, T; Singh, T, 2017) |
| "Depression was evaluated in all experimental groups using the tail suspension and sucrose preference test on days 1, 5, 10 and 15, 2 h after pentylenetetrazole challenge." | 1.46 | Adjuvant quercetin therapy for combined treatment of epilepsy and comorbid depression. ( Goel, RK; Kaur, T; Singh, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, T | 3 |
| Kaur, T | 2 |
| Goel, RK | 3 |
| BOOKER, WM | 2 |
| FRENCH, DM | 2 |
| CARLSSON, A | 1 |
| THEANDER, G | 1 |
| CHOPRA, BL | 1 |
| SCHERRER, P | 1 |
| LECLERC, J | 1 |
| LATOUCHE, M | 1 |
| LARSON, E | 1 |
| WYNN, MF | 1 |
| ADAMS, JP | 1 |
| VIDAL-TEIXIDOR, R | 1 |
| LISS, L | 1 |
| SOLZE, DA | 1 |
| FISCHER, R | 1 |
| KRAEMER, R | 1 |
| MELLINGHOFF, ML | 1 |
| MOLANO, PA | 1 |
| RHODES, C | 1 |
| Uzbay, TI | 2 |
| Kayir, H | 2 |
| Ceyhan, M | 1 |
| Yilmaz, I | 1 |
| Sezer, Z | 1 |
| Barkai, AI | 1 |
16 other studies available for pentylenetetrazole and Depressive Disorder
| Article | Year |
|---|---|
Ferulic Acid Supplementation for Management of Depression in Epilepsy.
Topics: Animals; Anticonvulsants; Brain; Coumaric Acids; Depression; Depressive Disorder; Disease Models, An | 2017 |
Evidence in support of using a neurochemistry approach to identify therapy for both epilepsy and associated depression.
Topics: Animals; Anticonvulsants; Brain; Depression; Depressive Disorder; Disease Models, Animal; Dopamine; | 2016 |
Adjuvant quercetin therapy for combined treatment of epilepsy and comorbid depression.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Combined Modality Therapy; Convulsants; Depressio | 2017 |
Re-evaluation of the effectiveness of metrazol as an analeptic agent in barbiturate depression.
Topics: Barbital; Barbiturates; Central Nervous System Stimulants; Depression; Depressive Disorder; Pentylen | 1948 |
On the stimulant and depressant effects of pentamethylenetetrazol in sodium diethyl barbiturate depression.
Topics: Barbital; Barbiturates; Central Nervous System Stimulants; Depression; Depressive Disorder; Humans; | 1946 |
A case of acute melancholia treated with cardiazol and insulin.
Topics: Bipolar Disorder; Depressive Disorder; Humans; Insulin; Mental Disorders; Pentylenetetrazole; Psycho | 1946 |
[Spectacular cure by cardiazol therapy of an atypical melancholia apparently incurable].
Topics: Convulsive Therapy; Depression; Depressive Disorder; Humans; Pentylenetetrazole | 1953 |
Studies of pentobarbital depression.
Topics: Barbiturates; Depression; Depressive Disorder; Humans; Pentobarbital; Pentylenetetrazole; Poisoning; | 1954 |
[On the treatment of depressive states in aged persons].
Topics: Dementia; Depression; Depressive Disorder; Humans; Inositol; Pentylenetetrazole; Psychotic Disorders | 1963 |
THE HISTOMORPHOLOGY OF EXPERIMENTAL EXCITATION.
Topics: Acridines; Coloring Agents; Depression; Depressive Disorder; Hippocampus; Histology; Lysergic Acid D | 1964 |
[Observations on the therapeutic use of sub-shock doses of cardiazol].
Topics: Convulsive Therapy; Depression; Depressive Disorder; Pentylenetetrazole; Shock | 1950 |
[Recent experiences with sub-shock cardiazol therapy].
Topics: Aged; Convulsive Therapy; Depression; Depressive Disorder; Humans; Pentylenetetrazole | 1950 |
Re-evaluation of the effectiveness of pentamethylenetetrazol (metrazol) as an analeptic agent during thiopental depression.
Topics: Central Nervous System Stimulants; Depression; Depressive Disorder; Humans; Pentylenetetrazole; Thio | 1950 |
Effects of tianeptine on onset time of pentylenetetrazole-induced seizures in mice: possible role of adenosine A1 receptors.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anticonvulsants; Antidep | 2007 |
Mirtazapine does not affect pentylenetetrazole- and maximal electroconvulsive shock-induced seizures in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Chi-Square Distribution; Depressive | 2007 |
Combined electroconvulsive and drug therapy.
Topics: Anesthesia; Apnea; Atropine; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect | 1985 |