pentylenetetrazole has been researched along with Dementia in 30 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (96.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SWENSON, WM | 2 |
| GRIMES, BP | 2 |
| FONG, TC | 1 |
| GROSS, M | 1 |
| FINN, MH | 1 |
| LIEBERMAN, AL | 1 |
| SCHWARTZ, SS | 1 |
| COOPER, M | 1 |
| SUTER, WB | 1 |
| LINDEN, ME | 1 |
| COURTNEY, D | 1 |
| HOWLAND, AO | 1 |
| BARRABEE, P | 1 |
| WINGATE, JH | 1 |
| PHILLIPS, BD | 1 |
| GREENBLATT, M | 1 |
| ERWIN, HJ | 2 |
| BUTTERWORTH, TR | 2 |
| JOHNSON, FG | 1 |
| SLUZYNSKI, L | 1 |
| ANDERSON, DE | 1 |
| RADICH, B | 1 |
| PROCTOR, RC | 1 |
| BAILEY, WH | 1 |
| MOREHOUSE, WG | 1 |
| TENNENT, JJ | 1 |
| VIDAL-TEIXIDOR, R | 1 |
| CLARKE, ET | 1 |
| WOLFF, K | 1 |
| LEAKE, CD | 1 |
| COHN, AG | 1 |
| COHN, WM | 1 |
| ROBINSON, DB | 1 |
| Rueda, N | 1 |
| Flórez, J | 1 |
| Martínez-Cué, C | 1 |
| Klawans, HL | 1 |
| Genovese, N | 1 |
| Cole, JO | 2 |
| Stotsky, BA | 2 |
| Lu, LM | 1 |
| Sniffin, CM | 1 |
| Gabrynowicz, JW | 1 |
| Dumbrill, M | 1 |
| LaBrecque, DC | 1 |
| Goldberg, RI | 1 |
| Ananth, JV | 1 |
| Deutsch, M | 1 |
| Ban, TA | 1 |
| Danto, BL | 1 |
| Salzberger, GJ | 1 |
2 reviews available for pentylenetetrazole and Dementia
| Article | Year |
|---|---|
THE CONFUSED GERIATRIC PATIENT.
Topics: Androgens; Dementia; Diagnosis, Differential; Estrogens; Geriatrics; Glutamates; Intracranial Arteri | 1964 |
Pharmacology of dementia.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aged; Aminopyridines; Central Nervous System | 1986 |
5 trials available for pentylenetetrazole and Dementia
| Article | Year |
|---|---|
Pharmacology of dementia.
Topics: 4-Aminopyridine; Acetylcholine; Adenosine Triphosphate; Aged; Aminopyridines; Central Nervous System | 1986 |
A controlled study of the efficacy of pentylenetetrazol (Metrazol) with hard-core hospitalized psychogeriatric patients.
Topics: Aged; Analysis of Variance; Chronic Disease; Clinical Trials as Topic; Dementia; Evaluation Studies | 1972 |
A clinical trial of leptazole with nicotinic acid in the management of psycho-geriatric patients.
Topics: Aged; Clinical Trials as Topic; Dementia; Female; Humans; Intracranial Arteriosclerosis; Male; Menta | 1968 |
A double-blind study of pentylenetetrazol combined with niacin in senile patients.
Topics: Aged; Clinical Trials as Topic; Dementia; Humans; Male; Nicotinic Acids; Pentylenetetrazole | 1967 |
Senilex in the treatment of geriatric patients.
Topics: Aged; Dementia; Female; Humans; Male; Nicotinic Acids; Pentylenetetrazole; Psychiatric Status Rating | 1971 |
24 other studies available for pentylenetetrazole and Dementia
| Article | Year |
|---|---|
Oral use of metrazol in senile patients.
Topics: Dementia; Mental Disorders; Patients; Pentylenetetrazole; Psychotic Disorders | 1953 |
Oral metrazol therapy in psychoses with cerebral arteriosclerosis.
Topics: Arteriosclerosis; Dementia; Intracranial Arteriosclerosis; Pentylenetetrazole; Psychotic Disorders | 1953 |
Oral metrazol therapy in psychotic senile and arteriosclerotic patients.
Topics: Arteriosclerosis; Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1954 |
Evaluation of intravenous and oral use of metrazol in hospitalized arteriosclerotic psychiatric patients.
Topics: Aged; Arteriosclerosis; Dementia; Disease; Humans; Mental Disorders; Pentylenetetrazole; Psychotic D | 1954 |
Oral metrazol therapy in senility; a preliminary report.
Topics: Aging; Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1955 |
Interdisciplinary research in the use of oral pentylenetetrazol (metrazol) in the emotional disorders of the aged; studies in gerontologic human relations. V.
Topics: Dementia; Geriatrics; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1956 |
Effects of L-glutavite compared with metrazol and vitamins on aged female psychotic patients.
Topics: Aged; Dementia; Disease; Glutamates; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorde | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Evaluation of nicozol in the care of the senile psychotic.
Topics: Dementia; Humans; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1957 |
Experiences with metrazol therapy in senile individuals.
Topics: Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1957 |
A re-evaluation of the oral use of metrazol in senile patients.
Topics: Dementia; Mental Disorders; Patients; Pentylenetetrazole; Psychotic Disorders | 1957 |
Metrazol treatment of the geriatric patient.
Topics: Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1957 |
An analeptic tranquilizer for senile psychoses; report of clinical and pharmacological studies of nicozol with reserpine.
Topics: Central Nervous System Stimulants; Dementia; Mental Disorders; Niacin; Pentylenetetrazole; Psychotic | 1958 |
Oral pentylenetetrazol in geriatric practice.
Topics: Aged; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1960 |
[On the treatment of depressive states in aged persons].
Topics: Dementia; Depression; Depressive Disorder; Humans; Inositol; Pentylenetetrazole; Psychotic Disorders | 1963 |
Observations on Benizol therapy in general practice. Ninety senile patients.
Topics: Arteriosclerosis; Dementia; General Practice; Geriatrics; Humans; Niacin; Nicotinic Acids; Pentylene | 1962 |
TREATING CONFUSED GERIATRIC PATIENTS.
Topics: Confusion; Dementia; Drug Therapy; Geriatrics; Glutamates; Humans; Mental Disorders; Pentylenetetraz | 1964 |
Oral metrazol treatment of senile and arteriosclerotic psychoses.
Topics: Arteriosclerosis; Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1955 |
Evaluation of certain drugs in geriatric patients: effects of chlorpromazine, reserpine, pentylenetetrazol U. S. P., and placebo on eighty-four female geriatric patients in a state hospital.
Topics: Chlorpromazine; Dementia; Female; Hospitals, State; Mental Disorders; Pentylenetetrazole; Psychotic | 1959 |
Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome.
Topics: Acetylcholine; Animals; Brain; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Disease Mod | 2008 |
Improving psychiatric drug therapy. A matter of dosage and choice.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anticoagulants; Antidepressive Agents; Antiparkinson Agents; B | 1974 |
Triflupromazine versus pentylenetetrazol-nicotinic acid for treatment of chronic brain disease on a general-hospital psychiatric service.
Topics: Aged; Dementia; Female; Humans; Intracranial Arteriosclerosis; Male; Nicotinic Acids; Pentylenetetra | 1969 |
Medical aspects and emotional responses to geriatric behavior problems.
Topics: Aged; Dementia; Emotions; Female; Humans; Mental Disorders; Middle Aged; Pentylenetetrazole | 1966 |