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pentylenetetrazole and Deficiency, Magnesium

pentylenetetrazole has been researched along with Deficiency, Magnesium in 5 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Research Excerpts

ExcerptRelevanceReference
" No differences in convulsive thresholds to Metrazol were obtained, however, between untreated Swiss-Webster mice and mice of the same strain made audiosuseptible by rubidium chloride intake or magnesium deficiency."3.66Metrazol thresholds in inbred and non-inbred audiosensitive mice. ( Alexander, GJ; Alexander, RB; Kopeloff, LM, 1981)
"Hydrogen sulfide (H2 S) is a gas transmitter that may mediate cerebral ischemic injury."1.40Aggravation of seizure-like events by hydrogen sulfide: involvement of multiple targets that control neuronal excitability. ( Chen, JG; Guan, XL; He, JG; Hu, ZL; Luo, Y; Wang, F; Wu, PF; Xiao, W; Zhang, JT; Zhou, J, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, W1
Guo, Y1
He, L1
Chen, C1
Luo, J1
Ma, Y1
Li, J1
Yang, Y1
Yang, Q1
Du, C1
Zhang, Y1
Li, Z1
Xu, X1
Tian, X1
Wang, X1
Luo, Y1
Wu, PF1
Zhou, J1
Xiao, W1
He, JG1
Guan, XL1
Zhang, JT1
Hu, ZL1
Wang, F1
Chen, JG1
Alexander, GJ1
Kopeloff, LM1
Alexander, RB1
Spasov, AA1
Iezhitsa, IN1
Kharitonova, MV1
Kravchenko, MS1
Vamecq, J1
Bac, P1
Herrenknecht, C1
Maurois, P1
Delcourt, P1
Stables, JP1

Other Studies

5 other studies available for pentylenetetrazole and Deficiency, Magnesium

ArticleYear
Overexpression of miRNA-137 in the brain suppresses seizure activity and neuronal excitability: A new potential therapeutic strategy for epilepsy.
    Neuropharmacology, 2018, Volume: 138

    Topics: Adolescent; Adult; Animals; Brain; Disease Models, Animal; Epilepsy; Female; Humans; Inhibitory Post

2018
Aggravation of seizure-like events by hydrogen sulfide: involvement of multiple targets that control neuronal excitability.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:5

    Topics: 4-Aminopyridine; Animals; Disease Models, Animal; Entorhinal Cortex; Hydrogen Sulfide; Magnesium Def

2014
Metrazol thresholds in inbred and non-inbred audiosensitive mice.
    Neurotoxicology, 1981, Volume: 2, Issue:1

    Topics: Acoustic Stimulation; Animals; Convulsants; Epilepsy, Reflex; Magnesium Deficiency; Male; Mice; Pent

1981
Effect of magnesium chloride and magnesium L-aspartate on seizure threshold in rats under conditions of dietary magnesium deficiency.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:2

    Topics: Animals; Anticonvulsants; Aspartic Acid; Magnesium Chloride; Magnesium Deficiency; Male; Pentylenete

2007
Synthesis and anticonvulsant and neurotoxic properties of substituted N-phenyl derivatives of the phthalimide pharmacophore.
    Journal of medicinal chemistry, 2000, Apr-06, Volume: 43, Issue:7

    Topics: Administration, Oral; Animals; Anticonvulsants; Batrachotoxins; Cerebral Cortex; Convulsants; Electr

2000