pentylenetetrazole has been researched along with Decerebrate Posturing in 22 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(iv) Generalized seizures induced by cortical perfusions showed a clear predominance of contractions in the muscles contralateral to the perfusion site, whereas perfusions in the MRF induced generalized seizures indistinguishable from those produced by i." | 1.27 | Comparative effects of topical perfusions of pentylenetetrazol in the mesencephalon and cerebral cortex of cats. ( Márquez, I; Pacheco, T; Velasco, F; Velasco, M, 1985) |
| "Results suggest that (i) PTZ-induced seizures start in the brain stem reticular formation and propagate to muscles by at least two different pathways: a pyramidal and an extrapyramidal pathway; (ii) that inhibition of seizure activity may start at the cortical level." | 1.26 | Specific and non-specific multiple unit activities during pentylenetetrazol seizures. I. Animals with 'encéphale isolé'. ( Romo, R; Velasco, F; Velasco, M, 1980) |
| "The hypothesis that the seizure susceptibility of chronically denervated cortex is due to interruption of recurrent inhibitory pathways was tested by examining the release of 3H-labeled gamma-aminobutyric acid ([3H]GABA) from chronic slabs and normal cortex of cats." | 1.26 | Release of exogenous gamma-[3H]aminobutyric acid during seizure activity in chronically denervated and normal cat cortex. ( Reiffenstein, RJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MAITI, A | 1 |
| DOMINO, EF | 1 |
| Arushanian, EB | 1 |
| Belozertsev, IuA | 1 |
| Collins, RJ | 1 |
| Tang, AH | 1 |
| Keasling, HH | 1 |
| Velasco, F | 5 |
| Velasco, M | 5 |
| Romo, R | 4 |
| Pacheco, MT | 1 |
| Patnaik, GK | 1 |
| Dhawan, BN | 1 |
| Mares, P | 1 |
| Pohl, M | 1 |
| Kubová, H | 1 |
| Zelízko, M | 1 |
| Reiffenstein, RJ | 1 |
| Pacheco, T | 1 |
| Márquez, I | 1 |
| Boyd, ES | 1 |
| Boyd, EH | 1 |
| Brown, LE | 1 |
| Grossmann, W | 1 |
| Jurna, I | 2 |
| Theres, C | 1 |
| Laycock, GM | 1 |
| Shulman, A | 1 |
| Wright, RD | 1 |
| Schomburg, ED | 1 |
| Kirsten, EB | 2 |
| Schoener, EP | 1 |
| Tseng, TC | 1 |
| Babington, RG | 1 |
| Horovitz, ZP | 1 |
| Menétrey, D | 1 |
| Decaud-Gasarabwe, J | 1 |
| Besson, JM | 1 |
| Hirsh, K | 1 |
| Wang, SC | 1 |
| Molnár, L | 1 |
22 other studies available for pentylenetetrazole and Decerebrate Posturing
| Article | Year |
|---|---|
EFFECTS OF ANESTHETIC CONCENTRATIONS OF CARBON DIOXIDE ON THE AMYGDALA AND NEURONALLY ISOLATED CEREBRAL CORTEX.
Topics: Amygdala; Anesthesia; Anesthesia, Inhalation; Anesthetics; Animals; Brain; Carbon Dioxide; Cerebral | 1964 |
[The effect of trimetin on facilitation and inhibition of the spinal reflex in stimulation of the reticular formation of the brain stem].
Topics: Animals; Anticonvulsants; Cats; Decerebrate State; Depression, Chemical; Electric Stimulation; Penty | 1966 |
Neuropharmacologic evaluation of 2-phenylimidazo-[1,2-a] pyrimidine hydrobromide (U-13,376B), an unusual strychnine antagonist.
Topics: Action Potentials; Anesthesia; Animals; Autonomic Agents; Cats; Caudate Nucleus; Chloralose; Decereb | 1967 |
Specific and non-specific multiple unit activities during pentylenetetrazol seizures. I. Animals with 'encéphale isolé'.
Topics: Action Potentials; Animals; Cats; Decerebrate State; Electroencephalography; Electromyography; Male; | 1980 |
Push-pull perfusion of pentylenetetrazol in the brain stem of 'encéphale isolé' cats.
Topics: Animals; Brain Mapping; Brain Stem; Cats; Decerebrate State; Male; Mesencephalon; Pentylenetetrazole | 1983 |
Topical perfusion of metrazol in the central nervous system of "encephale isole" cats.
Topics: Animals; Brain; Cats; Decerebrate State; Electroencephalography; Electromyography; Pentylenetetrazol | 1983 |
Specific and nonspecific multiple-unit activities during pentylenetetrazol seizures in animals with pretrigeminal brain stem transection.
Topics: Animals; Brain Stem; Cats; Decerebrate State; Electroencephalography; Male; Neurons; Pentylenetetraz | 1981 |
Mechanism of respiratory stimulant action of 4-(4-morpholinyl)-2,3-pentamethylenequinoline (compound 65/127) in cat.
Topics: Animals; Cats; Decerebrate State; Pentylenetetrazole; Quinolines; Respiration; Seizures | 1981 |
Is the site of action of ethosuximide in the hindbrain?
Topics: Animals; Anticonvulsants; Brain Stem; Clonazepam; Decerebrate State; Electrocardiography; Electroenc | 1994 |
Release of exogenous gamma-[3H]aminobutyric acid during seizure activity in chronically denervated and normal cat cortex.
Topics: Animals; Cats; Cerebral Cortex; Decerebrate State; Electric Stimulation; Female; gamma-Aminobutyric | 1979 |
Comparative effects of topical perfusions of pentylenetetrazol in the mesencephalon and cerebral cortex of cats.
Topics: Administration, Topical; Animals; Cats; Cerebral Cortex; Decerebrate State; Electroencephalography; | 1985 |
The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols.
Topics: Animals; Atropine; Blood Pressure; Brain; Cannabis; Cerebral Cortex; Chloralose; Chlorpromazine; Dec | 1974 |
The site of action of the optical isomers of 1-methyl-5-phenyl-5-propyl barbituric acid.
Topics: Action Potentials; Animals; Barbiturates; Binding Sites; Blood Pressure; Cats; Decerebrate State; El | 1974 |
Hypnotic-analeptic interaction at different neural levels in cats and rabbits.
Topics: Animals; Bemegride; Cats; Central Nervous System; Central Nervous System Stimulants; Decerebrate Sta | 1965 |
Supraspinal interactions of anesthetic, neuroleptic and analeptic drugs on the fusimotor effects of pinna stimulation in the cat.
Topics: Animals; Barbiturates; Bemegride; Blood Pressure; Brain Stem; Cats; Central Nervous System Stimulant | 1970 |
Antagonism of pentylenetetrazol excitation by anticonvulsants on single brain stem neurons.
Topics: Animals; Anticonvulsants; Brain Stem; Cats; Decerebrate State; Diazepam; Drug Antagonism; In Vitro T | 1972 |
Effects of tybamate and pentylenetetrazol on spinal interneurons.
Topics: Action Potentials; Animals; Carbamates; Cats; Decerebrate State; Electric Stimulation; Evoked Potent | 1972 |
Neuropharmacology of SQ 10,996, a compound with several therapeutic indications.
Topics: Amides; Animals; Anticonvulsants; Antidepressive Agents; Anxiety; Behavior, Animal; Carbamazepine; C | 1973 |
Effects of diazepam on dorsal root potentials induced by cortical paroxysmal activity.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Blood Pressure; Body Temperature; Cats; Cerebral Cor | 1973 |
Selective respiratory stimulating action of doxapram compared to pentylenetetrazaol.
Topics: Animals; Blood Pressure; Carbon Dioxide; Carotid Arteries; Catheterization; Cats; Chemoreceptor Cell | 1974 |
Role of brain stem in CBF regulation.
Topics: Anesthesia; Animals; Blood Pressure; Brain Stem; Carbon Dioxide; Cats; Cerebrovascular Circulation; | 1968 |
Depression of the dorsal root potential of the cat spinal cord by amidopyrine.
Topics: Aminopyrine; Animals; Cats; Decerebrate State; Electrophysiology; Injections, Intravenous; Pentylene | 1966 |