Page last updated: 2024-11-08

pentylenetetrazole and Cough

pentylenetetrazole has been researched along with Cough in 6 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"In order to understand the relationship between the cough and respiratory centers in the brain stem, we investigated the effects of respiratory stimulants, pentylenetetrazol (PTZ) and nikethamide (NK), and a respiratory depressant, pentobarbital (PB)on the cough reflex."3.66[Effects of respiratory drugs on the cough reflex]. ( Hosokawa, T; Kitagawa, H; Misawa, M; Yanaura, S, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yanaura, S1
Kitagawa, H1
Hosokawa, T1
Misawa, M1
Gaetti, R1
Lucchesi, M1
Tansini, G1
Cavallaro, G1
Palumbo-Vargas, O1
Bini, P1
Romagnoli, E1

Other Studies

6 other studies available for pentylenetetrazole and Cough

ArticleYear
[Effects of respiratory drugs on the cough reflex].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:1

    Topics: Animals; Cough; Dogs; Dose-Response Relationship, Drug; Male; Nikethamide; Pentobarbital; Pentylenet

1982
[Clinical experience with Cardiazol-Paracodin in bronchopathies of aged persons].
    Minerva medica, 1972, Apr-14, Volume: 63, Issue:28

    Topics: Acute Disease; Aged; Aging; Bronchitis; Chronic Disease; Cough; Drug Combinations; Humans; Laryngiti

1972
[Clinical experiences with pentamethylentetrazole-dihydrocodeine in the therapy of cough in patients with pulmonary].
    La Clinica terapeutica, 1971, Sep-30, Volume: 58, Issue:6

    Topics: Codeine; Cough; Humans; Male; Pentylenetetrazole; Tuberculosis, Pulmonary

1971
[Clinical considerations on a new antitussive agent].
    Minerva medica, 1971, Feb-28, Volume: 62, Issue:17

    Topics: Adolescent; Adult; Aged; Antitussive Agents; Bronchitis; Codeine; Cough; Female; Humans; Lung Diseas

1971
[On the therapy of cough in bronchial diseases of children].
    Minerva medica, 1971, Feb-28, Volume: 62, Issue:17

    Topics: Antitussive Agents; Bronchial Diseases; Bronchitis; Bronchopneumonia; Child; Child, Preschool; Codei

1971
[Clinical study of the cough sedative, expectorant and eupneic properties of the preparation, "Cardiazol-Paracodin" Knoll].
    Minerva medica, 1971, Feb-28, Volume: 62, Issue:17

    Topics: Bronchial Diseases; Codeine; Cough; Expectorants; Humans; Lung Diseases; Lung Neoplasms; Pentylenete

1971