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pentylenetetrazole and Constipation

pentylenetetrazole has been researched along with Constipation in 2 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.

Research Excerpts

ExcerptRelevanceReference
"Constipation is a common gastrointestinal disorder characterized by symptoms such as straining, hard stool, and infrequent defecation."5.42Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice. ( Inaloo, S; Moezi, L; Pirsalami, F, 2015)
"Constipation is a common gastrointestinal disorder characterized by symptoms such as straining, hard stool, and infrequent defecation."1.42Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice. ( Inaloo, S; Moezi, L; Pirsalami, F, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moezi, L1
Pirsalami, F1
Inaloo, S1
Takagi, H1
Kobayashi, S1
Kumakura, S1
Mori, M1
Koike, H1

Other Studies

2 other studies available for pentylenetetrazole and Constipation

ArticleYear
Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice.
    Epilepsy & behavior : E&B, 2015, Volume: 44

    Topics: Animals; Antidiarrheals; Constipation; Convulsants; Disease Models, Animal; Drug Interactions; Gastr

2015
[Pharmacological studies of a new potent antitussive agent, 14-hydroxy-dihydro-6 beta-thebainol-4-methyl ether (oxymethebanol)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Mar-20, Volume: 65, Issue:2

    Topics: Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Antitussive Agents; Blood Pressur

1969