pentylenetetrazole has been researched along with Concussive Convulsion in 8 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While CCI mice have no change in seizure susceptibility at 7d post-injury (dpi), at 70dpi they have reduced latency to PTZ-induced seizure onset, higher seizure frequency and longer seizure duration." | 1.91 | Delayed treatment with ceftriaxone reverses the enhanced sensitivity of TBI mice to chemically-induced seizures. ( Burns, MP; Harvey, AC; Longo, BM; Main, BS; Romariz, SAA, 2023) |
| "Their effects on seizure susceptibility and spontaneous epileptic seizures were evaluated with a pentylenetetrazol (PTZ) test in 2 weeks and with continuous video and wireless electroencephalography (EEG) monitoring between 2 and 6 weeks after injury, respectively." | 1.62 | Blocking receptor for advanced glycation end products (RAGE) or toll-like receptor 4 (TLR4) prevents posttraumatic epileptogenesis in mice. ( Chai, Z; Jin, X; Ma, C; Ping, X; Wang, W; White, FA, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Ping, X | 1 |
| Chai, Z | 1 |
| Wang, W | 1 |
| Ma, C | 1 |
| White, FA | 1 |
| Jin, X | 1 |
| Romariz, SAA | 1 |
| Main, BS | 1 |
| Harvey, AC | 1 |
| Longo, BM | 1 |
| Burns, MP | 1 |
| Cho, SJ | 1 |
| Park, E | 1 |
| Telliyan, T | 1 |
| Baker, A | 1 |
| Reid, AY | 1 |
| Pijet, B | 1 |
| Stefaniuk, M | 1 |
| Kostrzewska-Ksiezyk, A | 1 |
| Tsilibary, PE | 1 |
| Tzinia, A | 1 |
| Kaczmarek, L | 1 |
| Gerbatin, RR | 1 |
| Silva, LFA | 1 |
| Hoffmann, MS | 2 |
| Della-Pace, ID | 1 |
| do Nascimento, PS | 1 |
| Kegler, A | 1 |
| de Zorzi, VN | 1 |
| Cunha, JM | 1 |
| Botelho, P | 1 |
| Neto, JBT | 1 |
| Furian, AF | 2 |
| Oliveira, MS | 2 |
| Fighera, MR | 2 |
| Royes, LFF | 1 |
| Saraiva, AL | 1 |
| Ferreira, AP | 1 |
| Silva, LF | 1 |
| Dutra, FD | 1 |
| Royes, LF | 1 |
| Kharatishvili, I | 1 |
| Immonen, R | 1 |
| Gröhn, O | 1 |
| Pitkänen, A | 1 |
| Eliner, GI | 1 |
| Stepanov, AI | 1 |
| Filatov, PP | 1 |
8 other studies available for pentylenetetrazole and Concussive Convulsion
| Article | Year |
|---|---|
Blocking receptor for advanced glycation end products (RAGE) or toll-like receptor 4 (TLR4) prevents posttraumatic epileptogenesis in mice.
Topics: Animals; Disease Models, Animal; Epilepsy; Epilepsy, Post-Traumatic; Mice; Mice, Knockout; Pentylene | 2021 |
Delayed treatment with ceftriaxone reverses the enhanced sensitivity of TBI mice to chemically-induced seizures.
Topics: Animals; Brain Injuries, Traumatic; Ceftriaxone; Disease Models, Animal; Epilepsy, Post-Traumatic; G | 2023 |
Zebrafish model of posttraumatic epilepsy.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Brain Injuries, Traumatic; Convulsants; Disea | 2020 |
Elevation of MMP-9 Levels Promotes Epileptogenesis After Traumatic Brain Injury.
Topics: Animals; Brain Injuries, Traumatic; Cerebral Cortex; Epilepsy, Post-Traumatic; Genotype; Male; Matri | 2018 |
Delayed creatine supplementation counteracts reduction of GABAergic function and protects against seizures susceptibility after traumatic brain injury in rats.
Topics: Animals; Brain Injuries, Traumatic; Brain Waves; CA3 Region, Hippocampal; Cell Death; Creatine; Epil | 2019 |
Creatine reduces oxidative stress markers but does not protect against seizure susceptibility after severe traumatic brain injury.
Topics: Animals; Brain Injuries; Creatine; Dietary Supplements; Disease Models, Animal; Electroencephalograp | 2012 |
Quantitative diffusion MRI of hippocampus as a surrogate marker for post-traumatic epileptogenesis.
Topics: Animals; Brain Injuries; Cerebral Cortex; Convulsants; Diffusion Magnetic Resonance Imaging; Disease | 2007 |
[X-ray irradiation as a factor evincing cerebral epileptiform preparedness].
Topics: Animals; Carbon Dioxide; Chinchilla; Dose-Response Relationship, Radiation; Epilepsy, Post-Traumatic | 1975 |