pentylenetetrazole has been researched along with Complex Partial Epilepsy in 9 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "), status epilepticus (SE) of limbic seizures produced by kainic acid (KA, 10 mg/kg, i." | 3.73 | 5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats. ( González-Trujano, ME; Hong, E; López-Meraz, ML; Neri-Bazán, L; Rocha, LL, 2005) |
| "The objective of this study was to evaluate the interaction of the novel antiepileptic drug (AED), topiramate (TPM), with conventional AEDs against amygdala-kindled seizures in rats and pentylenetetrazol-induced convulsions in mice." | 3.72 | Effect of topiramate on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy. ( Borowicz, KK; Czuczwar, SJ; Duda, AM; Luszczki, JJ, 2003) |
| "Acetone has been shown to suppress experimental seizures." | 1.32 | Anticonvulsant properties of acetone, a brain ketone elevated by the ketogenic diet. ( Burnham, WM; Cortez, MA; Likhodii, SS; Murphy, P; Serbanescu, I; Snead, OC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, Y | 1 |
| Cai, S | 1 |
| Jiang, Y | 1 |
| Zhong, K | 1 |
| Wen, C | 1 |
| Ruan, Y | 1 |
| Chew, LA | 1 |
| Khanna, R | 1 |
| Xu, Z | 1 |
| Yu, J | 1 |
| Ahsan, MJ | 2 |
| Stables, JP | 1 |
| Taha, AY | 1 |
| Trepanier, MO | 1 |
| Ciobanu, FA | 1 |
| Taha, NM | 1 |
| Ahmed, M | 1 |
| Zeng, Q | 1 |
| Cheuk, WI | 1 |
| Ip, B | 1 |
| Filo, E | 1 |
| Scott, BW | 1 |
| Burnham, WM | 2 |
| Bazinet, RP | 1 |
| Borowicz, KK | 1 |
| Luszczki, JJ | 1 |
| Duda, AM | 1 |
| Czuczwar, SJ | 1 |
| Likhodii, SS | 1 |
| Serbanescu, I | 1 |
| Cortez, MA | 1 |
| Murphy, P | 1 |
| Snead, OC | 1 |
| RAND, RW | 1 |
| CRANDA, PH | 1 |
| WALTER, R | 1 |
| López-Meraz, ML | 1 |
| González-Trujano, ME | 1 |
| Neri-Bazán, L | 1 |
| Hong, E | 1 |
| Rocha, LL | 1 |
| Theodore, WH | 1 |
| Balish, M | 1 |
| Leiderman, D | 1 |
| Bromfield, E | 1 |
| Sato, S | 1 |
| Herscovitch, P | 1 |
1 review available for pentylenetetrazole and Complex Partial Epilepsy
| Article | Year |
|---|---|
Semicarbazone analogs as anticonvulsant agents: a review.
Topics: Animals; Anticonvulsants; Drug Design; Drug Evaluation, Preclinical; Electroshock; Epilepsy, Complex | 2013 |
8 other studies available for pentylenetetrazole and Complex Partial Epilepsy
| Article | Year |
|---|---|
Tetramethylpyrazine Reduces Epileptogenesis Progression in Electrical Kindling Models by Modulating Hippocampal Excitatory Neurotransmission.
Topics: Animals; Anticonvulsants; Anxiety; CA1 Region, Hippocampal; Calcium Channel Blockers; Calcium Channe | 2019 |
Psychomotor seizure test, neurotoxicity and in vitro neuroprotection assay of some semicarbazone analogues.
Topics: Animals; Anticonvulsants; Cell Death; Coloring Agents; Dose-Response Relationship, Drug; Drug Design | 2013 |
A minimum of 3 months of dietary fish oil supplementation is required to raise amygdaloid afterdischarge seizure thresholds in rats--implications for treating complex partial seizures.
Topics: Amygdala; Animals; Body Weight; Convulsants; Disease Models, Animal; Docosahexaenoic Acids; Dose-Res | 2013 |
Effect of topiramate on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, | 2003 |
Anticonvulsant properties of acetone, a brain ketone elevated by the ketogenic diet.
Topics: Acetone; Amygdala; Animals; Anticonvulsants; Ataxia; Brain Chemistry; Convulsants; Diabetes Mellitus | 2003 |
CHRONIC STEREOTACTIC IMPLANTATION OF DEPTH ELECTRODES FOR PSYCHOMOTOR EPILEPSY.
Topics: Brain; Electric Stimulation; Electrodes; Electroencephalography; Electrophysiology; Epilepsy; Epilep | 1964 |
5-HT1A receptor agonists modify epileptic seizures in three experimental models in rats.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Anticonvulsants; Con | 2005 |
Effect of seizures on cerebral blood flow measured with 15O-H2O and positron emission tomography.
Topics: Adult; Cerebrovascular Circulation; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, | 1996 |