Page last updated: 2024-11-08

pentylenetetrazole and Coma

pentylenetetrazole has been researched along with Coma in 12 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
" In the absence of other, more efficacious treatment methods, these therapies-such as insulin coma or atropine coma-brought at least some relief to those who suffered from serious mental disorders."3.74A few facts from the history of selected biological treatment methods in psychiatry. ( Jarema, M, 2008)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kanawaku, Y1
Hirakawa, K1
Koike, K1
Kanetake, J1
Ohno, Y1
Jarema, M1
WEISSMAN, FM1
COPINSCHI, G1
CORNIL, A1
THYS, O1
CAMPANA, C1
CARDINALI, G1
BURGOS, MH1
Seiler, N1
Sarhan, S1
Knoedgen, B1
Hornsperger, JM1
Sablone, M1
Masciocchi, A1
Myschetzky, A1
Derr, RF1
Zieve, L1
Crighel, E1
Constantinescu, V1
Spehlman, R1
Colley, B1

Reviews

1 review available for pentylenetetrazole and Coma

ArticleYear
[TREATMENT OF ACUTE BARBITURATE POISONING].
    Acta clinica Belgica, 1963, Volume: 18

    Topics: Amphetamine; Amphetamines; Barbiturates; Bemegride; Coma; Humans; Nikethamide; Pentylenetetrazole; P

1963

Other Studies

11 other studies available for pentylenetetrazole and Coma

ArticleYear
Pattern recognition analysis of proton nuclear magnetic resonance spectra of postmortem cerebrospinal fluid from rats with drug-induced seizure or coma.
    Legal medicine (Tokyo, Japan), 2017, Volume: 25

    Topics: Animals; Cerebrospinal Fluid; Coma; Convulsants; Discriminant Analysis; Hypnotics and Sedatives; Mag

2017
A few facts from the history of selected biological treatment methods in psychiatry.
    Neuro endocrinology letters, 2008, Volume: 29 Suppl 1

    Topics: Atropine; Clinical Trials as Topic; Coma; Convulsants; Convulsive Therapy; History, 20th Century; Hu

2008
Treatment of barbiturate coma with massive doses of.
    New York state journal of medicine, 1953, Dec-15, Volume: 53, Issue:24

    Topics: Ascomycota; Barbiturates; Coma; Humans; Pentylenetetrazole

1953
[Grave barbituric coma after administration of 800 mg. of picrotoxin and 20 gm. of pentmethylenetetrazole in 44 hours].
    Il Policlinico. Sezione pratica, 1955, Apr-18, Volume: 62, Issue:16

    Topics: Coma; Humans; Pentylenetetrazole; Picrotoxin; Poisoning; Suicide

1955
[Intoxication with barbiturates; 7 cases of grave coma treated with picrotoxin, metrazole and carbogen].
    El Dia medico, 1951, Mar-19, Volume: 23, Issue:12

    Topics: Ascomycota; Barbital; Barbiturates; Carbon Dioxide; Coma; Humans; Oxygen; Pentylenetetrazole; Picrot

1951
Enhanced endogenous ornithine concentrations protect against tonic seizures and coma in acute ammonia intoxication.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:2

    Topics: 3-Mercaptopropionic Acid; Ammonia; Animals; Brain Chemistry; Coma; Dialysis; Dizocilpine Maleate; El

1993
Clinical and EEG study of a case of barbiturate coma.
    Electroencephalography and clinical neurophysiology, 1967, Volume: 23, Issue:2

    Topics: Barbiturates; Coma; Electroencephalography; Humans; Pentylenetetrazole

1967
Shortening of coma duration in narcotic poisoning.
    International anesthesiology clinics, 1966,Summer, Volume: 4, Issue:2

    Topics: Central Nervous System Stimulants; Coma; Diuresis; Hexobarbital; Humans; Narcotics; Nikethamide; Pen

1966
Adenylate energy charge: relation to guanylate energy charge and the adenylate kinase equilibrium constant.
    Biochemical and biophysical research communications, 1972, Dec-18, Volume: 49, Issue:6

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Ammonia; Animal Nutritional Physiological Phenomena; A

1972
Dispersion curve of responses evoked by visual stimuli. Method for analysis of stochastic mechanisms involved in information processing in the brain.
    International journal of bio-medical computing, 1971, Volume: 2, Issue:1

    Topics: Adult; Alcohol Amnestic Disorder; Animals; Brain; Cats; Coma; Computers; Electroencephalography; Epi

1971
Effect of diazepam (Valium) on experimental seizures in unanesthetized cat.
    Neurology, 1968, Volume: 18, Issue:1 Pt 1

    Topics: Animals; Cats; Cerebral Cortex; Coma; Diazepam; Electroencephalography; Light; Pentylenetetrazole; P

1968