pentylenetetrazole has been researched along with Child Development Disorders, Pervasive in 2 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Susceptibility to absence seizures was examined by analysing the frequency and duration of spike-and-wave discharge (SWD) events and accompanying motor seizure activity induced by subcutaneous administration of low dosage (20 or 30mg/kg) PTZ." | 1.42 | Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism. ( Anderson, P; Argyropoulos, A; Hannan, AJ; Hill-Yardin, EL; Hosie, S; O'Brien, TJ; Rind, G, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, JA | 1 |
| Clesse, D | 1 |
| Spiegelhalter, C | 1 |
| Schwab, Y | 1 |
| Le Merrer, J | 1 |
| Kieffer, BL | 1 |
| Hill-Yardin, EL | 1 |
| Argyropoulos, A | 1 |
| Hosie, S | 1 |
| Rind, G | 1 |
| Anderson, P | 1 |
| Hannan, AJ | 1 |
| O'Brien, TJ | 1 |
2 other studies available for pentylenetetrazole and Child Development Disorders, Pervasive
| Article | Year |
|---|---|
Autistic-like syndrome in mu opioid receptor null mice is relieved by facilitated mGluR4 activity.
Topics: Aggression; Anilides; Animals; Anxiety; Behavior, Animal; Brain; Child Development Disorders, Pervas | 2014 |
Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.
Topics: Animals; Cell Adhesion Molecules, Neuronal; Child Development Disorders, Pervasive; Dose-Response Re | 2015 |