pentylenetetrazole has been researched along with Brain Swelling in 9 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eclampsia is characterized by high morbidity and mortality wordwide." | 5.51 | Magnesium sulfate attenuates brain edema by lowering AQP4 expression and inhibits glia-mediated neuroinflammation in a rodent model of eclampsia. ( Li, X; Liu, H; Yang, Y, 2019) |
| "Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 5.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
| "Eclampsia is characterized by high morbidity and mortality wordwide." | 1.51 | Magnesium sulfate attenuates brain edema by lowering AQP4 expression and inhibits glia-mediated neuroinflammation in a rodent model of eclampsia. ( Li, X; Liu, H; Yang, Y, 2019) |
| "Here, we hypothesized severe preeclampsia is a state of increased seizure susceptibility due to blood-brain barrier (BBB) disruption and neuroinflammation that lowers seizure threshold." | 1.40 | Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia. ( Chan, SL; Cipolla, MJ; Johnson, AC; LaMarca, B; Moseley, J; Nagle, KJ; Tremble, SM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Tran, NB | 1 |
| Lee, SJ | 1 |
| Li, X | 1 |
| Liu, H | 1 |
| Yang, Y | 1 |
| Johnson, AC | 1 |
| Tremble, SM | 1 |
| Chan, SL | 1 |
| Moseley, J | 1 |
| LaMarca, B | 1 |
| Nagle, KJ | 1 |
| Cipolla, MJ | 1 |
| Binder, DK | 2 |
| Oshio, K | 1 |
| Ma, T | 1 |
| Verkman, AS | 2 |
| Manley, GT | 1 |
| Papadopoulos, MC | 1 |
| Haggie, PM | 1 |
| Iwanowski, L | 1 |
| Wasilewski, R | 1 |
| Stern, P | 1 |
| Leonhardt, H | 2 |
9 other studies available for pentylenetetrazole and Brain Swelling
| Article | Year |
|---|---|
Effects of Gryllus bimaculatus and Oxya chinensis sinuosa extracts on brain damage via blood-brain barrier control and apoptosis in mice with pentylenetetrazol-induced epilepsy.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Endothelial Cells; Epil | 2023 |
Magnesium sulfate attenuates brain edema by lowering AQP4 expression and inhibits glia-mediated neuroinflammation in a rodent model of eclampsia.
Topics: Animals; Aquaporin 4; Astrocytes; Brain Edema; CA3 Region, Hippocampal; Cytokines; Disease Models, A | 2019 |
Magnesium sulfate treatment reverses seizure susceptibility and decreases neuroinflammation in a rat model of severe preeclampsia.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Convulsants; Diet, High-Fat; Disease Models, Anima | 2014 |
Increased seizure threshold in mice lacking aquaporin-4 water channels.
Topics: Action Potentials; Animals; Aquaporin 4; Aquaporins; Brain; Brain Edema; Convulsants; Disease Models | 2004 |
In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching.
Topics: Animals; Aquaporin 4; Aquaporins; Astrocytes; Brain Edema; Cerebral Cortex; Convulsants; Dextrans; D | 2004 |
[Observations on succinate and lactate dehydrogenase activity following cardiazol convulsions. (A histochemical study with microdensitometrical evaluation)].
Topics: Animals; Brain; Brain Damage, Chronic; Brain Edema; Densitometry; Frontal Lobe; Hippocampus; Hypoxia | 1973 |
[The influence of O-(beta-hydroxyethyl)-rutoside on the experimental edema of the brain].
Topics: Adrenocorticotropic Hormone; Animals; Brain Edema; Female; Male; Mice; Pentylenetetrazole; Rats; Rut | 1970 |
[On brain edema in different pericapillar structures of various grisea of the rabbit caused by pentamethylenetetrazole (cardiazol)].
Topics: Animals; Basement Membrane; Blood-Brain Barrier; Brain; Brain Edema; Capillaries; Cerebral Cortex; C | 1968 |
[Intercellular perivascular brain edema following pentamethylenetetrazole ("Cardiazol") convulsions].
Topics: Animals; Basement Membrane; Brain Edema; Microscopy, Electron; Pentylenetetrazole; Rabbits; Seizures | 1966 |