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pentylenetetrazole and Brain Diseases

pentylenetetrazole has been researched along with Brain Diseases in 14 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"Some previous reports indicate that the excitability of the brain may be increased for days following enflurane anesthesia."7.66Lidocaine and pentylenetetrazol seizure thresholds in cats are not reduced after enflurane anesthesia. ( Amory, DW; Heavner, JE, 1981)
"Some previous reports indicate that the excitability of the brain may be increased for days following enflurane anesthesia."3.66Lidocaine and pentylenetetrazol seizure thresholds in cats are not reduced after enflurane anesthesia. ( Amory, DW; Heavner, JE, 1981)
"A parenchymal brain granuloma is the final consequence of a localized inflammatory reaction against an infectious agent, particularly parasites."1.29Changes in the threshold of pentylenetetrazol-induced seizures in cats with a chronic granuloma in brain amygdala. ( Calvillo, M; Paz, C; Sotelo, J, 1993)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MUKAWA, J1
Williams, JR1
Csalany, L1
Misevic, G1
Heavner, JE1
Amory, DW1
Calvillo, M1
Paz, C1
Sotelo, J1
Burnard, DM1
Veale, WL1
Pittman, QJ1
Hernandez, TD1
Schallert, T1
Swartzwelder, HS1
Földi, M1
Obál, F1
Kahán, A1
Wagner, A1
Csanda, E1
Börcsök, E1
Lloyd-Smith, DL1
Van den Brenk, HA1
Harris, JW1
Rpopoviciu, L1
Asgian, B1
Fagarasanu, M1
Dulau, E1
Sandru, E1
Adams, AE1
Wood, JD1
Watson, WJ1
Baker, RN1
Klass, DW1

Reviews

1 review available for pentylenetetrazole and Brain Diseases

ArticleYear
The electroencephalogram as a diagnostic aid in neurosurgery: a review.
    Clinical neurosurgery, 1969, Volume: 16

    Topics: Adult; Age Factors; Amobarbital; Brain Diseases; Brain Injuries; Brain Neoplasms; Child; Child, Pres

1969

Trials

1 trial available for pentylenetetrazole and Brain Diseases

ArticleYear
[Lymphogenous encephalopathy: a new clinical picture and its management].
    Acta paediatrica Academiae Scientiarum Hungaricae, 1967, Volume: 8, Issue:2

    Topics: Adult; Animals; Brain Diseases; Cerebrospinal Fluid; Cerebrovascular Circulation; Child; Clinical Tr

1967

Other Studies

12 other studies available for pentylenetetrazole and Brain Diseases

ArticleYear
EFFECTS OF BRAINSTEM AND SUBCORTICAL LESIONS ON CORTICOGENIC EPILEPTIC CONVULSION WITH SPECIAL REFERENCE TO FOREL H-FIELD.
    Acta medicinae Okayama, 1964, Volume: 18

    Topics: Brain Diseases; Brain Stem; Cats; Cerebral Cortex; Electroencephalography; Electromyography; Epileps

1964
Drug therapy with or without group discussion: effects of various regimens on the behavior of geriatric patients in a mental hospital.
    Journal of the American Geriatrics Society, 1967, Volume: 15, Issue:1

    Topics: Aged; Brain Diseases; Chlorprothixene; Estradiol; Female; Hospitals, Psychiatric; Humans; Male; Ment

1967
Lidocaine and pentylenetetrazol seizure thresholds in cats are not reduced after enflurane anesthesia.
    Anesthesiology, 1981, Volume: 54, Issue:5

    Topics: Anesthesia; Animals; Brain Diseases; Cats; Enflurane; Female; Lidocaine; Male; Pentylenetetrazole; S

1981
Changes in the threshold of pentylenetetrazol-induced seizures in cats with a chronic granuloma in brain amygdala.
    Epilepsy research, 1993, Volume: 16, Issue:1

    Topics: Amygdala; Animals; Brain Diseases; Cats; Granuloma; Kaolin; Male; Pentylenetetrazole; Seizures; Tomo

1993
Prevention of arginine-vasopressin-induced motor disturbances by a potent vasopressor antagonist.
    Brain research, 1986, Jan-01, Volume: 362, Issue:1

    Topics: Animals; Arginine Vasopressin; Brain Diseases; Deamino Arginine Vasopressin; Drug Hypersensitivity;

1986
Seizures and recovery from experimental brain damage.
    Experimental neurology, 1988, Volume: 102, Issue:3

    Topics: Animals; Behavior, Animal; Brain Diseases; Forelimb; Locomotion; Male; Motor Cortex; Pentylenetetraz

1988
Central neurotoxicity after exposure to organic lead: susceptibility to seizures.
    Neuroscience letters, 1985, Jul-31, Volume: 58, Issue:2

    Topics: Animals; Brain Diseases; Drug Interactions; Limbic System; Male; Organometallic Compounds; Pentylene

1985
Brain dmage in rats following pentylenetetrazole and high pressure oxygen.
    Experientia, 1970, Dec-15, Volume: 26, Issue:12

    Topics: Animals; Brain; Brain Diseases; Cerebrovascular Circulation; Female; Hyperbaric Oxygenation; Paralys

1970
[Clinical, electroencephalographic and polygraphic studies of sleep in spasmophilia. Relation of spasmophilia to epilepsy, organic diseases of the nervous system, and neuroses].
    Revue neurologique, 1970, Volume: 123, Issue:4

    Topics: Bemegride; Brain Diseases; Electroencephalography; Electromyography; Epilepsy; Humans; Neurotic Diso

1970
[Frequency analysis of the flat EEG].
    Deutsche Zeitschrift fur Nervenheilkunde, 1968, Volume: 193, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Bemegride; Brain Diseases; Cerebral Cortex; Child; Child, Presc

1968
The effect of intraperitoneal injections of hyperosmotic solutions on convulsions induced by drugs and hyperbaric oxygen.
    Canadian journal of physiology and pharmacology, 1968, Volume: 46, Issue:4

    Topics: Aminobutyrates; Animals; Brain Diseases; Dehydration; Glucose; Hyperbaric Oxygenation; Hypertonic So

1968
The metrazol activation of the normal brain.
    Bulletin of the Los Angeles neurological societies, 1965, Volume: 30, Issue:4

    Topics: Adult; Brain; Brain Diseases; Electroencephalography; Epilepsy; Humans; Male; Pentylenetetrazole; Se

1965