pentylenetetrazole has been researched along with Body Weight in 65 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " infusion of phenobarbital to onset of loss of righting reflex showed that the starved animals required a larger body weight normalized dose and that they had higher phenobarbital concentrations in serum, serum water, brain and cerebrospinal fluid at the pharmacologic endpoint." | 7.67 | Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition. ( Levy, G; Wanwimolruk, S, 1987) |
| "Occasional, mild seizures occur in NPY-deficient mice and mutants are more susceptible to seizures induced by a GABA (gamma-aminobutyric acid) antagonist." | 5.29 | Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. ( Clegg, KE; Erickson, JC; Palmiter, RD, 1996) |
| " The mice displayed increased anxiety-like behaviour in several tests including elevated plus-maze and were more susceptible to pentylenetetrazole-induced seizures." | 3.73 | Behavioural phenotypes of hypomorphic KCC2-deficient mice. ( Airaksinen, MS; Rauvala, H; Savilahti, H; Tornberg, J; Voikar, V, 2005) |
| " We have studied the susceptibility to bicuculline and pentylenetetrazol-induced seizures in developing 10-, 20- and 30-day old rats, gestationally exposed to cocaine." | 3.69 | Prenatal cocaine: seizure susceptibility in rat offspring. ( de Feo, MR; Del Priore, D; Mecarelli, O, 1995) |
| " The parameters studies included body weight, pentobarbitone (50 mg/kg) sleeping time, chlorpromazine (6 mg/kg) induced motor incoordination and convulsions induced by leptazol (100 mg/kg) and electrical stimulation (18 mA for 0." | 3.68 | Effect of subacute insecticide exposure on body weight, drug responses & electrical convulsions in mice. ( Agarwal, AK; Sankaranarayanan, A; Sharma, PL, 1990) |
| " infusion of phenobarbital to onset of loss of righting reflex showed that the starved animals required a larger body weight normalized dose and that they had higher phenobarbital concentrations in serum, serum water, brain and cerebrospinal fluid at the pharmacologic endpoint." | 3.67 | Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition. ( Levy, G; Wanwimolruk, S, 1987) |
| "The threshold for seizure induction with progressive intravenous infusion of pentylenetrazole (PTZ) was evaluated in anesthetized Wistar rats after a ten-day oral administration of BD-AcAc2 (gavage)." | 1.43 | Different calorie restriction treatments have similar anti-seizure efficacy. ( Arnold, P; Coppola, G; D'Agostino, D; Monda, M; Pilla, R; Viggiano, A; Zeppa, P, 2016) |
| "The ketogenic diet (KD) controls seizure and improves cognition in patients with drug refractory epilepsy." | 1.43 | Ketogenic diet attenuates spatial and item memory impairment in pentylenetetrazol-kindled rats. ( Hou, Q; Jia, M; Jiang, Y; Lu, Y; Wang, B; Wang, X; Zhang, Z, 2016) |
| "The mechanism responsible for the anti-seizure effect of ketogenic diets is poorly understood." | 1.43 | Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats. ( Coppola, G; Iovane, V; Monda, M; Operto, FF; Pisano, S; Stoddard, M; Viggiano, A, 2016) |
| "Observed adverse effects differed between CsA treatment regimens and included reversible diarrhea, lowered body temperature, and tremor, the latter two of which were also induced by vehicle injections containing ethanol and/or polyethoxylated castor oil." | 1.42 | Different preparations, doses, and treatment regimens of cyclosporine A cause adverse effects but no robust changes in seizure thresholds in rats. ( Elger, DA; Gernert, M; Gey, L; Handreck, A; Mall, EM, 2015) |
| "Body weight was significantly higher in morphine groups than saline treated rats." | 1.40 | Effect of prenatal forced-swim stress and morphine co-administration on pentylentetrazol-induced epileptic behaviors in infant and prepubertal rats. ( Ebrahimi, L; Hashemi, P; Roshan-Milani, S; Saboory, E, 2014) |
| "Common withdrawal symptoms include anxiety, increased reactivity to stimuli and increased seizure susceptibility as well as the risk of increased seizure severity." | 1.38 | Running wheel activity protects against increased seizure susceptibility in ethanol withdrawn male rats. ( Devaud, LL; Khurana, RC; McCulley, WD; Rosenwasser, AM; Walls, SA, 2012) |
| "The incidence of spontaneous seizures has been reported to be increased in sporadic AD as well as in the early onset autosomal dominant forms of AD." | 1.38 | Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice. ( Bales, K; Cirrito, JR; Delong, C; Holtzman, DM; Hunter, JM; Kinley, RD; Koger, D; Lin, S; Liu, F; Paul, SM; Restivo, JL; Sullivan, PM; Zhao, L, 2012) |
| "All subjects were seizure tested by using the PTZ infusion test." | 1.33 | A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats. ( Abdelmalik, PA; Burnham, WM; Clarke, J; Likhodii, S; Nylen, K, 2005) |
| "In fact, the tests involving maximal seizures actually showed proconvulsant effects." | 1.31 | The MCT ketogenic diet: effects on animal seizure models. ( Burnham, WM; Cunnane, SC; Dell, C; Iracleous, C; Likhodii, SS; Mendonca, A; Musa, K; Thavendiranathan, P, 2000) |
| " In the subchronic experiments, rats were exposed to PCE at a dosage of 5 and 50 mg/kg in corn oil, 5 days per week for 8 weeks." | 1.31 | Behavioural effects of tetrachloroethylene exposure in rats: acute and subchronic studies. ( Chan, MH; Chen, HH; Fu, SH, 2002) |
| " These results suggest that long-term administration of neurosteroids pregnenolone sulfate or dehydroepiandrosterone sulfate produces proconvulsant effects." | 1.30 | Proconvulsant effects of neurosteroids pregnenolone sulfate and dehydroepiandrosterone sulfate in mice. ( Kulkarni, SK; Reddy, DS, 1998) |
| "Results indicate that seizure threshold was significantly elevated with increasing ketogenic ratios (i." | 1.30 | Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat. ( Bough, KJ; Chen, RS; Eagles, DA, 1999) |
| "Occasional, mild seizures occur in NPY-deficient mice and mutants are more susceptible to seizures induced by a GABA (gamma-aminobutyric acid) antagonist." | 1.29 | Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. ( Clegg, KE; Erickson, JC; Palmiter, RD, 1996) |
| "In addition, ED and latency to convulsion were measured in WSP and WSR mice at 5 different concentrations of PTZ." | 1.28 | Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice. ( Crabbe, JC; Cross, SJ; Kosobud, AE, 1992) |
| "The sensitivity to insulin hypoglycemic convulsions has been shown to decrease at early times (16 and 24 hr) and increase at later times (1 week) after gold thioglucose (GTG) treatment." | 1.26 | Change in sensitivity to insulin hypoglycemic convulsions after gold thioglucose treatment: time course of development. ( Fish, KW; Holliday, JF; Luby, JL; Marrazzi, MA, 1981) |
| "Tonic seizure was seen at birth, myoclonic jerks at 2 weeks of age, myoclonic seizure and catalepsy at 3 weeks of age." | 1.25 | Maturation of convulsogenic activity induced by leptazol in the albino rat. ( de Casrilevitz, M; Engelhardt, E; Esbérard, CA, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (36.92) | 18.7374 |
| 1990's | 14 (21.54) | 18.2507 |
| 2000's | 14 (21.54) | 29.6817 |
| 2010's | 12 (18.46) | 24.3611 |
| 2020's | 1 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Dos Santos, FM | 1 |
| Pflüger, PF | 1 |
| Lazzarotto, L | 1 |
| Uczay, M | 1 |
| de Aguida, WR | 1 |
| da Silva, LS | 1 |
| Boaretto, FBM | 1 |
| de Sousa, JT | 1 |
| Picada, JN | 1 |
| da Silva Torres, IL | 1 |
| Pereira, P | 1 |
| Menezes, FP | 1 |
| Da Silva, RS | 1 |
| Ebrahimi, L | 1 |
| Saboory, E | 1 |
| Roshan-Milani, S | 1 |
| Hashemi, P | 1 |
| Handreck, A | 1 |
| Mall, EM | 1 |
| Elger, DA | 1 |
| Gey, L | 1 |
| Gernert, M | 1 |
| Viggiano, A | 2 |
| Pilla, R | 1 |
| Arnold, P | 1 |
| Monda, M | 2 |
| D'Agostino, D | 1 |
| Zeppa, P | 1 |
| Coppola, G | 2 |
| Grauncke, AC | 1 |
| Souza, TL | 1 |
| Ribeiro, LR | 2 |
| Brant, F | 1 |
| Machado, FS | 1 |
| Oliveira, MS | 2 |
| Jiang, Y | 1 |
| Lu, Y | 1 |
| Jia, M | 1 |
| Wang, X | 1 |
| Zhang, Z | 1 |
| Hou, Q | 1 |
| Wang, B | 1 |
| Stoddard, M | 1 |
| Pisano, S | 1 |
| Operto, FF | 1 |
| Iovane, V | 1 |
| Porta, N | 1 |
| Vallée, L | 1 |
| Lecointe, C | 1 |
| Bouchaert, E | 1 |
| Staels, B | 1 |
| Bordet, R | 1 |
| Auvin, S | 2 |
| Souza, MA | 1 |
| Furian, AF | 1 |
| Rambo, LM | 1 |
| Lima, FD | 1 |
| Dalla Corte, LC | 1 |
| Silva, LF | 1 |
| Retamoso, LT | 1 |
| Dalla Corte, CL | 1 |
| Puntel, GO | 1 |
| de Avila, DS | 1 |
| Soares, FA | 1 |
| Fighera, MR | 1 |
| de Mello, CF | 1 |
| Royes, LF | 1 |
| Ghasemi, M | 1 |
| Shafaroodi, H | 1 |
| Karimollah, AR | 1 |
| Gholipour, T | 1 |
| Nezami, BG | 1 |
| Ebrahimi, F | 1 |
| Dehpour, AR | 1 |
| Said, SA | 1 |
| El-Agamy, DS | 1 |
| McCulley, WD | 1 |
| Walls, SA | 1 |
| Khurana, RC | 1 |
| Rosenwasser, AM | 1 |
| Devaud, LL | 1 |
| Hunter, JM | 1 |
| Cirrito, JR | 1 |
| Restivo, JL | 1 |
| Kinley, RD | 1 |
| Sullivan, PM | 1 |
| Holtzman, DM | 1 |
| Koger, D | 1 |
| Delong, C | 1 |
| Lin, S | 1 |
| Zhao, L | 1 |
| Liu, F | 1 |
| Bales, K | 1 |
| Paul, SM | 1 |
| Taha, AY | 2 |
| Trepanier, MO | 1 |
| Ciobanu, FA | 1 |
| Taha, NM | 1 |
| Ahmed, M | 1 |
| Zeng, Q | 1 |
| Cheuk, WI | 1 |
| Ip, B | 1 |
| Filo, E | 1 |
| Scott, BW | 1 |
| Burnham, WM | 4 |
| Bazinet, RP | 1 |
| Eagles, DA | 2 |
| Boyd, SJ | 1 |
| Kotak, A | 1 |
| Allan, F | 1 |
| GOERES, E | 1 |
| LANGE, P | 1 |
| JUNG, F | 1 |
| Calderón Guzmán, D | 1 |
| Espitia Vázquez, I | 1 |
| Barragán Mejía, G | 1 |
| Labra Ruiz, N | 1 |
| Rodríguez Pérez, R | 1 |
| Santamaria del Angel, D | 1 |
| Ayala Guerrero, F | 1 |
| Juárez Olguín, H | 1 |
| Compan, V | 1 |
| Zhou, M | 1 |
| Grailhe, R | 1 |
| Gazzara, RA | 1 |
| Martin, R | 1 |
| Gingrich, J | 1 |
| Dumuis, A | 1 |
| Brunner, D | 1 |
| Bockaert, J | 1 |
| Hen, R | 1 |
| Wu, HM | 1 |
| Liang, YC | 1 |
| Chen, SH | 2 |
| Huang, CC | 1 |
| Tsai, JJ | 1 |
| Hsieh, CL | 1 |
| Hsu, KS | 1 |
| Huang, TP | 1 |
| Ho, IK | 1 |
| Mehendale, HM | 1 |
| Chiu, CS | 1 |
| Brickley, S | 1 |
| Jensen, K | 1 |
| Southwell, A | 1 |
| Mckinney, S | 1 |
| Cull-Candy, S | 1 |
| Mody, I | 1 |
| Lester, HA | 1 |
| Tornberg, J | 1 |
| Voikar, V | 1 |
| Savilahti, H | 1 |
| Rauvala, H | 1 |
| Airaksinen, MS | 1 |
| Nylen, K | 1 |
| Likhodii, S | 1 |
| Abdelmalik, PA | 1 |
| Clarke, J | 1 |
| Shin, D | 1 |
| Mazarati, A | 1 |
| Sankar, R | 1 |
| Raffo, E | 1 |
| François, J | 1 |
| Ferrandon, A | 1 |
| Koning, E | 1 |
| Nehlig, A | 1 |
| Huot, PS | 1 |
| Reza-López, S | 1 |
| Prayitno, NR | 1 |
| Kang, JX | 1 |
| Ma, DW | 1 |
| Luby, JL | 1 |
| Holliday, JF | 3 |
| Fish, KW | 2 |
| Marrazzi, MA | 3 |
| Churchill, B | 1 |
| da Silva, VA | 1 |
| Ribeiro, MJ | 1 |
| Masur, J | 1 |
| Bogdanov, NN | 1 |
| Poletaeva, II | 1 |
| Popova, NV | 1 |
| de Feo, MR | 1 |
| Del Priore, D | 1 |
| Mecarelli, O | 1 |
| Taukulis, HK | 1 |
| Erickson, JC | 1 |
| Clegg, KE | 1 |
| Palmiter, RD | 1 |
| Palencia, G | 1 |
| Calvillo, M | 1 |
| Sotelo, J | 1 |
| Kim, E | 1 |
| Lowenson, JD | 1 |
| MacLaren, DC | 1 |
| Clarke, S | 1 |
| Young, SG | 1 |
| Reddy, DS | 1 |
| Kulkarni, SK | 1 |
| Becker, HC | 1 |
| Veatch, LM | 1 |
| Diaz-Granados, JL | 1 |
| Acheson, SK | 1 |
| Richardson, R | 1 |
| Swartzwelder, HS | 1 |
| Bough, KJ | 1 |
| Chen, RS | 1 |
| Thavendiranathan, P | 1 |
| Mendonca, A | 1 |
| Dell, C | 1 |
| Likhodii, SS | 1 |
| Musa, K | 1 |
| Iracleous, C | 1 |
| Cunnane, SC | 1 |
| Chen, HH | 1 |
| Chan, MH | 1 |
| Fu, SH | 1 |
| Hommes, OR | 1 |
| ten Berge, EJ | 1 |
| Jansen, MJ | 1 |
| Kok, JC | 1 |
| Yehuda, S | 1 |
| Carasso, RL | 1 |
| Okonmah, AD | 1 |
| Soliman, KF | 1 |
| Kosobud, AE | 1 |
| Cross, SJ | 1 |
| Crabbe, JC | 1 |
| Martínez, E | 1 |
| de Vera, N | 1 |
| Artigas, F | 1 |
| Jänicke, B | 1 |
| Coper, H | 1 |
| Agarwal, AK | 1 |
| Sankaranarayanan, A | 1 |
| Sharma, PL | 1 |
| Wanwimolruk, S | 1 |
| Levy, G | 1 |
| Cassel, JC | 1 |
| Kelche, C | 1 |
| Will, BE | 1 |
| Litterst, CL | 1 |
| Mimnaugh, EG | 1 |
| Edelman, S | 1 |
| Peters, E | 1 |
| Miller, E | 1 |
| Van Loon, EJ | 1 |
| Takagi, H | 1 |
| Kobayashi, S | 1 |
| Kumakura, S | 1 |
| Mori, M | 1 |
| Koike, H | 1 |
| Leite, JR | 1 |
| Carlini, EA | 1 |
| Chesher, GB | 1 |
| Jackson, DM | 1 |
| Uhlemann, ER | 1 |
| Neims, AH | 1 |
| de Casrilevitz, M | 1 |
| Engelhardt, E | 1 |
| Esbérard, CA | 1 |
| Prabhu, VG | 1 |
| Oester, YT | 1 |
| Danielsen, J | 1 |
| Ellebjerg, J | 1 |
| Okabe, Y | 1 |
| Iizuka, H | 1 |
| Asahi, K | 1 |
| Yanagida, T | 1 |
| Iturrian, WB | 1 |
| Fink, GB | 1 |
| Mukawa, J | 1 |
| Hayakawa, T | 1 |
| Nakatani, S | 1 |
| Iwata, K | 1 |
| Kobayashi, K | 1 |
| Arai, Y | 1 |
| Gorski, RA | 1 |
| Davis, WM | 1 |
| Su, MQ | 1 |
1 trial available for pentylenetetrazole and Body Weight
| Article | Year |
|---|---|
Comparable EEG activation by megimide and metrazol.
Topics: Adolescent; Adult; Aged; Bemegride; Body Weight; Clinical Trials as Topic; Electroencephalography; E | 1966 |
64 other studies available for pentylenetetrazole and Body Weight
| Article | Year |
|---|---|
Gamma-Decanolactone Alters the Expression of GluN2B, A
Topics: Animals; Body Weight; Cyclooxygenase 2; DNA Damage; Female; Lactones; Male; Mice; Neuroprotective Ag | 2021 |
The influence of temperature on adult zebrafish sensitivity to pentylenetetrazole.
Topics: Animals; Anticonvulsants; Body Weight; Convulsants; Dizocilpine Maleate; Female; Fever; Male; Models | 2017 |
Effect of prenatal forced-swim stress and morphine co-administration on pentylentetrazol-induced epileptic behaviors in infant and prepubertal rats.
Topics: Animals; Animals, Newborn; Body Weight; Female; Male; Morphine; Narcotics; Pentylenetetrazole; Pregn | 2014 |
Different preparations, doses, and treatment regimens of cyclosporine A cause adverse effects but no robust changes in seizure thresholds in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Body Weight; Convulsants; Cyclosp | 2015 |
Different calorie restriction treatments have similar anti-seizure efficacy.
Topics: Analysis of Variance; Animals; Anticonvulsants; Blood Glucose; Body Weight; Butylene Glycols; Calori | 2016 |
Increased susceptibility to pentylenetetrazol following survival of cerebral malaria in mice.
Topics: Animals; Body Weight; Convulsants; Disease Models, Animal; Disease Susceptibility; Electroencephalog | 2016 |
Ketogenic diet attenuates spatial and item memory impairment in pentylenetetrazol-kindled rats.
Topics: Animals; Body Weight; Diet, Ketogenic; Kindling, Neurologic; Male; Maze Learning; Memory Disorders; | 2016 |
Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Blood Glucose; Body Weight; Convulsants; Diet, Ke | 2016 |
Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, exerts anticonvulsive properties.
Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Body Weight; Diet, Ketogenic; Disease Models, | 2009 |
Swimming training prevents pentylenetetrazol-induced inhibition of Na+, K+-ATPase activity, seizures, and oxidative stress.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Catalase; Disease Models, Animal; Elec | 2009 |
ATP-sensitive potassium channels contribute to the time-dependent alteration in the pentylenetetrazole-induced seizure threshold in diabetic mice.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cromakalim; Diabetes Mellitus, Experiment | 2010 |
Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.
Topics: Acetylcysteine; Animals; Anticonvulsants; Body Weight; Chemical and Drug Induced Liver Injury; Convu | 2010 |
Running wheel activity protects against increased seizure susceptibility in ethanol withdrawn male rats.
Topics: Alcohol Withdrawal Seizures; Animals; Behavior, Animal; Body Weight; Energy Intake; Male; Motor Acti | 2012 |
Emergence of a seizure phenotype in aged apolipoprotein epsilon 4 targeted replacement mice.
Topics: Aging; Amyloid beta-Peptides; Animals; Apolipoprotein E4; Behavior, Animal; Biomarkers; Body Weight; | 2012 |
A minimum of 3 months of dietary fish oil supplementation is required to raise amygdaloid afterdischarge seizure thresholds in rats--implications for treating complex partial seizures.
Topics: Amygdala; Animals; Body Weight; Convulsants; Disease Models, Animal; Docosahexaenoic Acids; Dose-Res | 2013 |
Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Convulsants; Dietary Carbohydrates; Dietary Fats; Energ | 2003 |
[ANIMAL EXPERIMENTAL STUDIES ON THE CHARACTERIZATION OF THE MECHANISM OF ACTION OF SULFONAMIDES WITH ANALEPTIC ACTION].
Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Weight; Central Nervous System Stimulant | 1964 |
Effect of valproic acid on levels of GABA and glutamic acid in pentylenetetrazole-damaged rat brain.
Topics: Animals; Anticonvulsants; Body Weight; Brain Chemistry; Convulsants; gamma-Aminobutyric Acid; Glutam | 2003 |
Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice.
Topics: Animals; Behavior, Animal; Body Weight; Convulsants; Eating; Environment; Gene Targeting; Locomotion | 2004 |
Valacyclovir treatment ameliorates the persistently increased pentylenetetrazol-induced seizure susceptibility in mice with herpes simplex virus type 1 infection.
Topics: Acyclovir; Animals; Antiviral Agents; Behavior, Animal; Body Weight; Disease Susceptibility; Dose-Re | 2004 |
Assessment of neurotoxicity induced by oral administration of chlordecone (Kepone) in the mouse.
Topics: Animals; Body Weight; Chlordecone; Convulsants; Dose-Response Relationship, Drug; Drinking; Eating; | 1981 |
GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.
Topics: Animals; Anxiety; Ataxia; Behavior, Animal; Benzodiazepines; Body Temperature; Body Weight; Cerebell | 2005 |
Behavioural phenotypes of hypomorphic KCC2-deficient mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Blotting, Wester | 2005 |
A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats.
Topics: 3-Hydroxybutyric Acid; Age Factors; Animals; Blood Glucose; Body Weight; Dietary Fats; Disease Model | 2005 |
The utility of testing pentylenetetrazol threshold.
Topics: Age Factors; Animals; Body Weight; Brain; Convulsants; Diet Therapy; Disease Models, Animal; Epileps | 2006 |
Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Caloric Restriction; Cerebral Cortex; Di | 2008 |
Seizure resistance in fat-1 transgenic mice endogenously synthesizing high levels of omega-3 polyunsaturated fatty acids.
Topics: Animals; Body Weight; Brain; Chromatography, Gas; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatt | 2008 |
Change in sensitivity to insulin hypoglycemic convulsions after gold thioglucose treatment: time course of development.
Topics: Animals; Aurothioglucose; Body Weight; Brain; Female; Gold; Gold Sodium Thiomalate; Hypoglycemia; In | 1981 |
Comparison of insulin hypoglycemia-induced and fluoroacetate-induced convulsions in gold thioglucose lesioned mice.
Topics: Animals; Aurothioglucose; Blood Glucose; Body Weight; Citrates; Citric Acid; Female; Fluoroacetates; | 1981 |
Effects of bipiperidyl mustard (BPM) lesions on insulin hypoglycemic convulsions.
Topics: Animals; Aurothioglucose; Body Weight; Eating; Female; Hypoglycemia; Insulin; Mice; Mice, Inbred CBA | 1982 |
Developmental, behavioral, and pharmacological characteristics of rat offspring from mothers receiving ethanol during gestation or lactation.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Body Weight; Female; Lactation; Male; Maternal Behavior | 1980 |
[Mice selected on the basis of low weight are more selective to the convulsant effect of pentylenetetrazole].
Topics: Animals; Body Weight; Convulsants; Mice; Mice, Inbred Strains; Pentylenetetrazole; Seizures | 1995 |
Prenatal cocaine: seizure susceptibility in rat offspring.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Body Weight; Brain; Cocaine; Female; Humans; In | 1995 |
Conditional attenuation of the antipentylenetetrazol activity of chlordiazepoxide.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Chlordiazepoxide; Chlorpromazine; Conditioning, Operant; | 1993 |
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y.
Topics: Animals; Body Weight; Eating; Feeding Behavior; Female; Food Deprivation; GABA Antagonists; Gene Tar | 1996 |
Chronic malnutrition caused by a corn-based diet lowers the threshold for pentylenetetrazol-induced seizures in rats.
Topics: Animals; Body Weight; Brain; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; | 1996 |
Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.
Topics: Animals; Asparagine; Aspartic Acid; Body Weight; Death, Sudden; DNA Primers; Female; Growth Disorder | 1997 |
Proconvulsant effects of neurosteroids pregnenolone sulfate and dehydroepiandrosterone sulfate in mice.
Topics: Animals; Body Weight; Convulsants; Dehydroepiandrosterone Sulfate; Injections, Subcutaneous; Male; M | 1998 |
Repeated ethanol withdrawal experience selectively alters sensitivity to different chemoconvulsant drugs in mice.
Topics: Animals; Body Weight; Convulsants; Ethanol; Kainic Acid; Kindling, Neurologic; Male; Mice; Mice, Inb | 1998 |
Developmental changes in seizure susceptibility during ethanol withdrawal.
Topics: Age Factors; Animals; Body Weight; Central Nervous System Depressants; Convulsants; Ethanol; Pentyle | 1999 |
Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Body Weight; Convulsants; Diet; Differential Threshold; Disea | 1999 |
The MCT ketogenic diet: effects on animal seizure models.
Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Body Weight; Dietary Fats, Unsaturated; Electroshock; M | 2000 |
Behavioural effects of tetrachloroethylene exposure in rats: acute and subchronic studies.
Topics: Animals; Behavior, Animal; Body Weight; Convulsants; Injections, Intravenous; Male; Motor Activity; | 2002 |
Effects of change in dietary folic acid content on pentylenetetrazol seizure threshold in rat.
Topics: Animals; Body Weight; Brain; Differential Threshold; Electroencephalography; Female; Folic Acid; Fol | 1977 |
The effects of d-amphetamine and temperature on p-cresol and pentylenetetrazol induced convulsions.
Topics: Animals; Body Weight; Cresols; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship | 1977 |
CNS stimulation effect on the sexual maturation of the female rat.
Topics: Animals; Body Weight; Female; Gonadotropins, Equine; Organ Size; Ovary; Pentylenetetrazole; Rats; Se | 1978 |
Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice.
Topics: Animals; Body Weight; Brain; Disease Susceptibility; Dose-Response Relationship, Drug; Environment; | 1992 |
Differential response of rat brain polyamines to convulsant agents.
Topics: Animals; Biogenic Polyamines; Body Weight; Brain; Convulsants; Hexachlorocyclohexane; Kainic Acid; M | 1991 |
Effects of age and drugs on food and fluid intake.
Topics: Aging; Amphetamines; Animals; Behavior, Animal; Benzodiazepines; Body Weight; Diazepam; Drinking; Dr | 1991 |
Effect of subacute insecticide exposure on body weight, drug responses & electrical convulsions in mice.
Topics: Animals; Body Weight; Chlorpromazine; Drug Interactions; Insecticides; Male; Mice; Mice, Inbred Stra | 1990 |
Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition.
Topics: Animals; Blood Proteins; Body Weight; Central Nervous System; Diet; Dietary Carbohydrates; Dietary P | 1987 |
Susceptibility to pentylenetetrazol-induced and audiogenic seizures in rats with selective fimbria-fornix lesions and intrahippocampal septal grafts.
Topics: Acoustic Stimulation; Animals; Body Weight; Female; Hippocampus; Neural Pathways; Pentylenetetrazole | 1987 |
Distribution and biochemical effects of pentylenetetrazol in brains of swine treated with a polychlorinated biphenyl.
Topics: Aminobutyrates; Animals; Body Weight; Brain; Caudate Nucleus; Cerebellum; Chromatography, Gas; Dihyd | 1974 |
[Pharmacological studies of a new potent antitussive agent, 14-hydroxy-dihydro-6 beta-thebainol-4-methyl ether (oxymethebanol)].
Topics: Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Antitussive Agents; Blood Pressur | 1969 |
Failure to obtain "cannabis-directed behavior" and abstinence syndrome in rats chronically treated with cannabis sativa extracts.
Topics: Adrenal Glands; Animals; Barbiturates; Behavior, Animal; Body Weight; Brain; Cannabis; Drinking Beha | 1974 |
The effect of withdrawal from cannabis on pentylenetetrazol convulsive threshold in mice.
Topics: Animals; Body Weight; Cannabis; Dronabinol; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male | 1974 |
Anticonvulsant properties of the ketogenic diet in mice.
Topics: Age Factors; Animals; Anticonvulsants; Body Weight; Caseins; Dietary Fats; Electroshock; Fasting; Fe | 1972 |
Maturation of convulsogenic activity induced by leptazol in the albino rat.
Topics: Age Factors; Animals; Body Weight; Brain Stem; Catalepsy; Central Nervous System; Female; Humans; In | 1971 |
Neuromuscular functions of mature mice following neonatal monosodium glutamate.
Topics: Animals; Animals, Newborn; Body Weight; Crowding; Dextroamphetamine; Female; Food Additives; Glutama | 1971 |
[Influence of food deprivation on efficacy and toxicity of drugs in mice].
Topics: Acetates; Aminopyrine; Analgesics; Animals; Anticonvulsants; Blood Glucose; Blood Proteins; Body Wei | 1969 |
Influence of age and brief auditory conditioning upon experimental seizures in mice.
Topics: Acoustic Stimulation; Age Factors; Animals; Biological Evolution; Body Weight; Brain; Conditioning, | 1969 |
[Characteristics of Metrazol and Megimide for activation of seizure discharge--experimental study and their clinical uses].
Topics: Adolescent; Adult; Animals; Bemegride; Body Weight; Cats; Cerebral Cortex; Child; Electroencephalogr | 1967 |
Protection against the neural organizing effect of exogenous androgen in the neonatal female rat.
Topics: Animals; Animals, Newborn; Body Weight; Chlorpromazine; Desoxycorticosterone; Female; Hypothalamus; | 1968 |
Effects of adrenalectomy and repeated convulsions on responses of rats to flurothyl.
Topics: Adrenalectomy; Animals; Body Weight; Ethers; Fluorine; Male; Pentylenetetrazole; Rats; Seizures; Sod | 1969 |