pentylenetetrazole has been researched along with Blood Pressure, High in 8 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was to examine the effect on the blood-brain barrier function of a rapid blood pressure elevation and the duration of this pressure during bicuculline and pentylenetetrazol-induced seizures." | 3.68 | The effect of acute hypertension on blood-brain barrier permeability to albumin during experimentally induced epileptic seizures. ( Kaya, M; Oztaş, B, 1991) |
| "In rabbits subjected to bicuculline (BC)- or pentylenetetrazole (PTZ)-seizures of 3 or 20 min duration or to adrenaline-induced hypertension, specific gravity (SG) was measured bilaterally in 15 regional brain areas in order to detect possible associations between the regionally limited blood-brain barrier openings due to these insults (see Nitsch and Klatzo 1983) and the presence of brain edema." | 3.67 | Specific gravity increases and brain water content decreases during short epileptiform seizures in discrete rabbit brain areas. ( Fujiwara, K; Klatzo, I; Kuroiwa, T; Nitsch, C, 1984) |
| "Pentylenetetrazol-induced seizure produces less disruption of the blood-brain barrier in right cerebral hemisphere than in left cerebral hemisphere in female rats." | 1.30 | Asymmetrical changes in blood-brain barrier permeability during pentylenetetrazol-induced seizures and in acute hypertension. ( Oztaş, B, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MORIN, G | 2 |
| CORRIOL, J | 2 |
| Nitsch, C | 1 |
| Fujiwara, K | 1 |
| Kuroiwa, T | 1 |
| Klatzo, I | 1 |
| Oztaş, B | 2 |
| Kaya, M | 1 |
| Chen, G | 1 |
| Ensor, CR | 1 |
| Bohner, B | 1 |
| Secor, HV | 1 |
| DeBardeleben, JF | 1 |
| Beleslin, BB | 1 |
| Beleslin, DB | 1 |
8 other studies available for pentylenetetrazole and Blood Pressure, High
| Article | Year |
|---|---|
[Mechanism of arterial hypertension produced by intravenous injection of cardiazol dogs treated with curare and in dogs treated and not treated with chloralose].
Topics: Animals; Chloralose; Curare; Dogs; Hypertension; Hypnotics and Sedatives; Injections, Intravenous; P | 1955 |
[Relation between the hypertensive and epiletogen effects of penta-methylene-tetrazole].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Pentylenetetrazole; Rubiaceae; S | 1957 |
Specific gravity increases and brain water content decreases during short epileptiform seizures in discrete rabbit brain areas.
Topics: Animals; Bicuculline; Blood; Blood-Brain Barrier; Body Water; Brain; Epilepsy; Epinephrine; Hyperten | 1984 |
Asymmetrical changes in blood-brain barrier permeability during pentylenetetrazol-induced seizures and in acute hypertension.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Capillary Permeability; Convulsants; Female; Functiona | 1998 |
The effect of acute hypertension on blood-brain barrier permeability to albumin during experimentally induced epileptic seizures.
Topics: Acute Disease; Albumins; Animals; Bicuculline; Blood Pressure; Blood-Brain Barrier; Evans Blue; Fema | 1991 |
The pharmacology of 2-(ethylamino)-2-(2-thienyl)-cyclohexanone-HCl (CI-634).
Topics: Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Catalepsy; Cats; Central Nervou | 1969 |
Syntheses and screening of some trifluoromethyl pyrazoles.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents; Blood Pressure; Fluorin | 1971 |
On the mechanism of hypertensive effect of leptazol.
Topics: Animals; Blood Pressure; Female; Hypertension; Male; Pentylenetetrazole; Rats | 1967 |