pentylenetetrazole has been researched along with Bipolar Disorder in 10 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Lower doses of valproate and carbamazepine were required to prevent hyperactivity compared to doses required to block tonic-clonic seizures induced by pentylenetetrazole." | 3.73 | Evaluation of the effects of lamotrigine, valproate and carbamazepine in a rodent model of mania. ( Arban, R; Brackenborough, K; Gerrard, P; Large, C; Maraia, G; Wilson, A; Winyard, L, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHOPRA, BL | 1 |
| Ellis, LD | 1 |
| Soanes, KH | 1 |
| Arban, R | 1 |
| Maraia, G | 1 |
| Brackenborough, K | 1 |
| Winyard, L | 1 |
| Wilson, A | 1 |
| Gerrard, P | 1 |
| Large, C | 1 |
| Barkai, AI | 1 |
| Villeneuve, A | 1 |
| Fink, M | 1 |
| van Laere, JE | 1 |
| Romaszewska, K | 1 |
| Wlosinska, I | 1 |
| Jus, A | 1 |
| Varga, E | 1 |
| Haits, G | 1 |
| Schulz, H | 1 |
| Müller, J | 1 |
| Roth, B | 1 |
| Stein, J | 1 |
1 review available for pentylenetetrazole and Bipolar Disorder
| Article | Year |
|---|---|
CNS effects of convulsive therapy: significance for a theory of depressive psychosis.
Topics: Alpha Rhythm; Amobarbital; Antidepressive Agents; Bipolar Disorder; Brain; Depression; Electroconvul | 1972 |
1 trial available for pentylenetetrazole and Bipolar Disorder
| Article | Year |
|---|---|
[Fluorothyl: pharmacological aspect and clinical use].
Topics: Affective Symptoms; Animals; Bemegride; Bipolar Disorder; Central Nervous System Stimulants; Clinica | 1968 |
8 other studies available for pentylenetetrazole and Bipolar Disorder
| Article | Year |
|---|---|
A case of acute melancholia treated with cardiazol and insulin.
Topics: Bipolar Disorder; Depressive Disorder; Humans; Insulin; Mental Disorders; Pentylenetetrazole; Psycho | 1946 |
A larval zebrafish model of bipolar disorder as a screening platform for neuro-therapeutics.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Disorder; Dark Ada | 2012 |
Evaluation of the effects of lamotrigine, valproate and carbamazepine in a rodent model of mania.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Carbamazepine; Central Nervous Syst | 2005 |
Combined electroconvulsive and drug therapy.
Topics: Anesthesia; Apnea; Atropine; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect | 1985 |
[Medical aspects of anxiety].
Topics: Angina Pectoris; Anxiety; Bipolar Disorder; Brain; Humans; Limbic System; Neurotic Disorders; Pentyl | 1973 |
[Evolution of attacks of periodic manic-depressive psychosis (intermittent double form and intermittent melancholia) and methods of treatment].
Topics: Adolescent; Adult; Bipolar Disorder; Convulsive Therapy; Electroconvulsive Therapy; Female; Humans; | 1967 |
Therapeutic efficacy and the treatment of psychoses over the last three decades.
Topics: Adult; Bipolar Disorder; Convulsive Therapy; Electroconvulsive Therapy; Female; Humans; Imipramine; | 1968 |
Bioelectrically controlled convulsion treatment of endogenous psychoses under general anaesthesia and muscular relaxation. I. Changes of the passive EEG.
Topics: Adult; Aged; Anesthesia, General; Bipolar Disorder; Convulsive Therapy; Electrocardiography; Electro | 1968 |