pentylenetetrazole has been researched along with Behavior Disorders in 70 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Flurothyl inhalation-induced seizures were as clinically effective as electrical inductions with lesser effects on memory functions." | 8.90 | The chemical induction of seizures in psychiatric therapy: were flurothyl (indoklon) and pentylenetetrazol (metrazol) abandoned prematurely? ( Cooper, K; Fink, M, 2014) |
| " Flurothyl inhalation-induced seizures were as clinically effective as electrical inductions with lesser effects on memory functions." | 4.90 | The chemical induction of seizures in psychiatric therapy: were flurothyl (indoklon) and pentylenetetrazol (metrazol) abandoned prematurely? ( Cooper, K; Fink, M, 2014) |
| " In contrast, impaired performance in the Morris water maze test and decreased anxiety-like behavior persisted together with an increased susceptibility to pentylenetetrazole-induced seizures suggesting alterations in neural activity patterns." | 3.85 | Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow. ( Angenstein, F; Goldschmidt, J; Hummel, R; Pöttker, B; Radyushkin, K; Schäfer, MKE; Stöber, F, 2017) |
| " In the absence of other, more efficacious treatment methods, these therapies-such as insulin coma or atropine coma-brought at least some relief to those who suffered from serious mental disorders." | 3.74 | A few facts from the history of selected biological treatment methods in psychiatry. ( Jarema, M, 2008) |
| "Patients with epilepsy are often affected by not only seizures but also a variety of cognitive and psychiatric comorbidities that further impair their quality of life." | 2.61 | [Neurobehavioral Comorbidities in Pentylenetetrazol-kindled Mice and Role of the α4β2 Nicotinic Acetylcholine Receptor]. ( Takechi, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 64 (91.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (2.86) | 29.6817 |
| 2010's | 4 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takechi, K | 1 |
| Pöttker, B | 1 |
| Stöber, F | 1 |
| Hummel, R | 1 |
| Angenstein, F | 1 |
| Radyushkin, K | 1 |
| Goldschmidt, J | 1 |
| Schäfer, MKE | 1 |
| Cooper, K | 1 |
| Fink, M | 1 |
| Jarema, M | 1 |
| DE RAMIREZ DE ARELLANO, MI | 1 |
| COSSA, P | 1 |
| Kragh, JV | 1 |
| ZISKIND, E | 1 |
| SJAARDEMA, H | 1 |
| BERCEL, NA | 1 |
| SCHNACK, GF | 2 |
| SHAKOW, D | 2 |
| LIVELY, ML | 2 |
| CHOPRA, BL | 1 |
| SWENSON, WM | 2 |
| GRIMES, BP | 2 |
| SEIDEL, H | 1 |
| SILVER, AA | 1 |
| NAGEL, H | 1 |
| BERTELLI, A | 1 |
| ROVATI, V | 1 |
| LEVY, S | 1 |
| LIEBERMAN, AL | 2 |
| PACELLA, BL | 1 |
| LAUFER, MW | 1 |
| DENHOFF, E | 1 |
| RUBIN, EZ | 1 |
| LEIBERMAN, DM | 1 |
| HOENIG, J | 1 |
| HACKER, M | 1 |
| GROSS, M | 1 |
| FINN, MH | 1 |
| SCHWARTZ, SS | 1 |
| COOPER, M | 1 |
| THOMPSON, LJ | 1 |
| PROCTOR, RC | 2 |
| SUTER, WB | 1 |
| LINDEN, ME | 1 |
| COURTNEY, D | 1 |
| HOWLAND, AO | 1 |
| BARRABEE, P | 1 |
| WINGATE, JH | 1 |
| PHILLIPS, BD | 1 |
| GREENBLATT, M | 1 |
| ERWIN, HJ | 2 |
| BUTTERWORTH, TR | 2 |
| DENCKER, SJ | 2 |
| SILFVERSKIOLD, W | 2 |
| JOHNSON, FG | 1 |
| KOMORA, EJ | 1 |
| PADULA, LJ | 1 |
| SLUZYNSKI, L | 1 |
| ANDERSON, DE | 1 |
| RADICH, B | 1 |
| BAGGE, L | 1 |
| SCHLAUG, R | 1 |
| BAILEY, WH | 1 |
| MOREHOUSE, WG | 1 |
| SICHENEDER, T | 1 |
| NAHUNEK, K | 3 |
| HATORI, S | 1 |
| HAYDU, GG | 1 |
| LANGE, HS | 1 |
| WHITTIER, JR | 1 |
| TENNENT, JJ | 1 |
| DEB, AK | 1 |
| BHATTACHARJEE, S | 1 |
| VELLOSO, FM | 1 |
| PAPROCKI, J | 2 |
| BOECHAT, P | 1 |
| PLZAK, M | 1 |
| FISCHER, R | 1 |
| LEDEREROVA, E | 1 |
| TOMANOVA, M | 1 |
| MISUREC, J | 2 |
| GOLDBERG, RI | 1 |
| SHUMAN, FI | 1 |
| LEAKE, CD | 1 |
| CHEN, G | 1 |
| BASS, P | 1 |
| LEFFMAN, H | 1 |
| PERLO, VP | 1 |
| HOLLISTER, L | 1 |
| FITZPATRICK, WF | 1 |
| COHN, AG | 1 |
| COHN, WM | 1 |
| ROBINSON, DB | 1 |
| McCrae, N | 1 |
| SARGANT, W | 1 |
| Williams, JR | 1 |
| Csalany, L | 1 |
| Misevic, G | 1 |
| Crook, T | 1 |
| Barkai, AI | 1 |
| Cole, JO | 1 |
| Stotsky, BA | 1 |
| Hofling, CK | 1 |
| Winslow, WW | 1 |
| Kellner, R | 1 |
| Thigpen, CH | 1 |
| Tourney, G | 1 |
| Gabrynowicz, JW | 1 |
| Dumbrill, M | 1 |
| Vikhliaev, IuI | 1 |
| Klygul', TA | 1 |
| Prokudin, VN | 1 |
| Adronati, SA | 1 |
| Castelli, G | 1 |
| Nardini, L | 1 |
| Sommer, H | 1 |
| Quandt, J | 1 |
| Miller, JF | 1 |
| Salzberger, GJ | 1 |
3 reviews available for pentylenetetrazole and Behavior Disorders
| Article | Year |
|---|---|
[Neurobehavioral Comorbidities in Pentylenetetrazol-kindled Mice and Role of the α4β2 Nicotinic Acetylcholine Receptor].
Topics: Animals; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Down-Regulation; Epilepsy; Isoxa | 2019 |
The chemical induction of seizures in psychiatric therapy: were flurothyl (indoklon) and pentylenetetrazol (metrazol) abandoned prematurely?
Topics: Animals; Electroconvulsive Therapy; Flurothyl; Humans; Memory Disorders; Mental Disorders; Pentylene | 2014 |
Drug therapy.
Topics: Affective Symptoms; Antidepressive Agents; Butyrophenones; Cannabis; Clinical Trials as Topic; Human | 1972 |
2 trials available for pentylenetetrazole and Behavior Disorders
| Article | Year |
|---|---|
Drug therapy.
Topics: Affective Symptoms; Antidepressive Agents; Butyrophenones; Cannabis; Clinical Trials as Topic; Human | 1972 |
A clinical trial of leptazole with nicotinic acid in the management of psycho-geriatric patients.
Topics: Aged; Clinical Trials as Topic; Dementia; Female; Humans; Intracranial Arteriosclerosis; Male; Menta | 1968 |
66 other studies available for pentylenetetrazole and Behavior Disorders
| Article | Year |
|---|---|
Traumatic brain injury causes long-term behavioral changes related to region-specific increases of cerebral blood flow.
Topics: Animals; Brain Injuries, Traumatic; Cerebrovascular Circulation; Conditioning, Psychological; Diseas | 2017 |
A few facts from the history of selected biological treatment methods in psychiatry.
Topics: Atropine; Clinical Trials as Topic; Coma; Convulsants; Convulsive Therapy; History, 20th Century; Hu | 2008 |
Effect of metrazol on the electrical excitability of the respiratory center when depressed by phenobarbital.
Topics: Barbital; Barbiturates; Mental Disorders; Pentylenetetrazole; Phenobarbital; Psychomotor Agitation; | 1947 |
Respective indications of cures by insulin, cardiazolic and electric shocks.
Topics: Insulin; Mental Disorders; Pentylenetetrazole; Psychotic Disorders; Schizophrenia; Seizures; Therape | 1946 |
Respective indications of insulin therapy, cardiazoltherapy and electrochoctherapy.
Topics: Insulin; Mental Disorders; Pentylenetetrazole; Psychotic Disorders; Schizophrenia; Seizures; Therape | 1946 |
Shock therapy in Danish psychiatry.
Topics: Convulsants; Convulsive Therapy; Denmark; History, 20th Century; Hospitals, Psychiatric; Humans; Men | 2010 |
Minimal electroencephalographic response to metrazol as a method for measuring the convulsive threshold for use in human beings.
Topics: Brain; Electroencephalography; Mental Disorders; Pentylenetetrazole; Psychotic Disorders; Seizures; | 1946 |
Studies in insulin and metrazol therapy; the differential prognostic value of some psychological tests.
Topics: Humans; Insulin; Intelligence Tests; Mental Disorders; Pentylenetetrazole; Prognosis; Psychological | 1945 |
Studies in insulin and metrazol therapy; differential effects on some psychological functions.
Topics: Humans; Insulin; Mental Disorders; Pentylenetetrazole; Seizures; Therapeutics | 1945 |
A case of acute melancholia treated with cardiazol and insulin.
Topics: Bipolar Disorder; Depressive Disorder; Humans; Insulin; Mental Disorders; Pentylenetetrazole; Psycho | 1946 |
Oral use of metrazol in senile patients.
Topics: Dementia; Mental Disorders; Patients; Pentylenetetrazole; Psychotic Disorders | 1953 |
Effects of metrazol and nicotinamide on psychic and mental disorders in the geriatric patient; a preliminary report.
Topics: Aged; Humans; Mental Disorders; Niacin; Niacinamide; Nicotinic Acids; Patients; Pentylenetetrazole; | 1953 |
[Stressing activity of cardiazol and coramine].
Topics: Adrenal Cortex; Mental Disorders; Nikethamide; Pentylenetetrazole | 1953 |
Pharmacological treatment of aged patients in a state mental hospital.
Topics: Aged; Hospitals, Psychiatric; Hospitals, State; Humans; Mental Disorders; Niacin; Nicotinic Acids; P | 1953 |
Subconvulsive intravenous metrazol therapy in mental patients; a preliminary report.
Topics: Aged; Mental Disorders; Mentally Ill Persons; Pentylenetetrazole | 1954 |
Photic stimulation of psychiatric patients.
Topics: Barbiturates; Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Photic Stimul | 1953 |
Photo-metrazol activation in children.
Topics: Child; Electroencephalography; Epilepsy; Humans; Infant; Mental Disorders; Pentylenetetrazole | 1954 |
The metrazol-flicker threshold in neuro-psychiatric patients.
Topics: Electroencephalography; Epilepsy; Humans; Mental Disorders; Patients; Pentylenetetrazole | 1954 |
Oral metrazol therapy in psychotic senile and arteriosclerotic patients.
Topics: Arteriosclerosis; Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1954 |
Evaluation of intravenous and oral use of metrazol in hospitalized arteriosclerotic psychiatric patients.
Topics: Aged; Arteriosclerosis; Dementia; Disease; Humans; Mental Disorders; Pentylenetetrazole; Psychotic D | 1954 |
The effect of nicotinic acid and pentylenetetrazol in the therapy of psychiatric symptoms of cerebral arteriosclerosis.
Topics: Arteriosclerosis; Humans; Intracranial Arteriosclerosis; Mental Disorders; Niacin; Nicotinic Acids; | 1954 |
Oral metrazol therapy in senility; a preliminary report.
Topics: Aging; Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1955 |
Interdisciplinary research in the use of oral pentylenetetrazol (metrazol) in the emotional disorders of the aged; studies in gerontologic human relations. V.
Topics: Dementia; Geriatrics; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1956 |
Effects of L-glutavite compared with metrazol and vitamins on aged female psychotic patients.
Topics: Aged; Dementia; Disease; Glutamates; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorde | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
The geriatric patient; metalex in treatment.
Topics: Dementia; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
Some experiences with metrazol in geriatric practice.
Topics: Brain; Cardiovascular System; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Diso | 1956 |
[Modified cardiazol shock therapy].
Topics: Convulsive Therapy; Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychos | 1957 |
[Modified cardiazol shock therapy].
Topics: Convulsive Therapy; Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychos | 1957 |
[Modified cardiazol shock therapy].
Topics: Convulsive Therapy; Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychos | 1957 |
[Modified cardiazol shock therapy].
Topics: Convulsive Therapy; Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychos | 1957 |
Evaluation of nicozol in the care of the senile psychotic.
Topics: Dementia; Humans; Mental Disorders; Niacin; Nicotinic Acids; Pentylenetetrazole; Psychotic Disorders | 1957 |
Combined use of metrazol and succinylcholine in the therapy of mental disorders.
Topics: Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychosurgery; Psychotherap | 1957 |
Experiences with metrazol therapy in senile individuals.
Topics: Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1957 |
A re-evaluation of the oral use of metrazol in senile patients.
Topics: Dementia; Mental Disorders; Patients; Pentylenetetrazole; Psychotic Disorders | 1957 |
Metrazol treatment of the geriatric patient.
Topics: Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1957 |
An unusual complication in connection with metrazol-shock treatment; a case report.
Topics: Convulsive Therapy; Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychot | 1957 |
An analeptic tranquilizer for senile psychoses; report of clinical and pharmacological studies of nicozol with reserpine.
Topics: Central Nervous System Stimulants; Dementia; Mental Disorders; Niacin; Pentylenetetrazole; Psychotic | 1958 |
[The significance of tetrazole (cardiazol) in modern psychiatric therapy].
Topics: Electroconvulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychosurgery; Psychotherap | 1958 |
[Pentazol-ataractic treatment of psychoses; preliminary report].
Topics: Chlorpromazine; Mental Disorders; Pentylenetetrazole; Psychosurgery; Psychotic Disorders; Reserpine; | 1959 |
Activating effect of photometrazol on the EEG of various psychoses and neuroses cases.
Topics: Electroencephalography; Light; Mental Disorders; Neurotic Disorders; Pentylenetetrazole; Photobiolog | 1958 |
Effects of Metrazolvitamin administration in chronic psychoses.
Topics: Chronic Disease; Mental Disorders; Nutrition Therapy; Pentylenetetrazole; Psychotic Disorders; Vitam | 1961 |
Oral pentylenetetrazol in geriatric practice.
Topics: Aged; Dementia; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1960 |
Cardiazol convulsion therapy in some psychotic cases.
Topics: Convulsive Therapy; Humans; Mental Disorders; Pentylenetetrazole; Psychotic Disorders; Seizures | 1959 |
[Metrazole therapy under the protection of narcosis and synthetic curariform drug].
Topics: Atropine; Convulsive Therapy; Humans; Mental Disorders; Methohexital; Neuromuscular Nondepolarizing | 1963 |
[PHOTOMETRAZOLE THRESHOLD DURING THERAPY WITH VARIOUS ANTIDEPRESSIVE AGENTS].
Topics: Antidepressive Agents; Imipramine; Mental Disorders; Neurasthenia; Pentylenetetrazole; Psychotic Dis | 1963 |
[PHOTOMETRAZOLE THRESHOLD DURING THERAPY WITH VARIOUS ANTIDEPRESSIVE AGENTS].
Topics: Antidepressive Agents; Imipramine; Mental Disorders; Neurasthenia; Pentylenetetrazole; Psychotic Dis | 1963 |
[BIOLOGICAL TREATMENTS IN PSYCHIATRIC DAY HOSPITALS].
Topics: Convulsive Therapy; Electroconvulsive Therapy; Equipment and Supplies; Hospitals, Psychiatric; Human | 1963 |
PENTAMETHYLENE TETRAZOL, VASODILATOR, VITAMIN THERAPY FOR MENTALLY CONFUSED GERIATRIC PATIENTS: DOUBLE-BLIND STUDY.
Topics: Aged; Biomedical Research; Cerebral Arteries; Confusion; Double-Blind Method; Geriatrics; Humans; Hy | 1964 |
TREATING CONFUSED GERIATRIC PATIENTS.
Topics: Confusion; Dementia; Drug Therapy; Geriatrics; Glutamates; Humans; Mental Disorders; Pentylenetetraz | 1964 |
CERTAIN PHARMACOLOGICAL PROPERTIES OF 3-ETHYL-2-METHYL-2-PHENYLSUCCINIMIDE.
Topics: Anticonvulsants; Mental Disorders; Meprobamate; Mice; Pentylenetetrazole; Peptic Ulcer; Pharmacology | 1964 |
Metrazol and combined photic-metrazol activated electroencephalography in epileptic, schizophrenic, psychoneurotic, and psychopathic patients.
Topics: Electroencephalography; Epilepsy; Humans; Light; Mental Disorders; Pentylenetetrazole | 1955 |
Oral metrazol in the psychoses associated with old age.
Topics: Humans; Mental Disorders; Pentylenetetrazole; Psychotherapy; Psychotic Disorders | 1955 |
Oral metrazol treatment of senile and arteriosclerotic psychoses.
Topics: Arteriosclerosis; Dementia; Mental Disorders; Pentylenetetrazole; Psychotic Disorders | 1955 |
Evaluation of certain drugs in geriatric patients: effects of chlorpromazine, reserpine, pentylenetetrazol U. S. P., and placebo on eighty-four female geriatric patients in a state hospital.
Topics: Chlorpromazine; Dementia; Female; Hospitals, State; Mental Disorders; Pentylenetetrazole; Psychotic | 1959 |
[Photometrazole threshold in Thioridazine therapy].
Topics: Electroconvulsive Therapy; Mental Disorders; Pentylenetetrazole; Psychosurgery; Psychotherapy; Thior | 1962 |
'A violent thunderstorm': Cardiazol treatment in British mental hospitals.
Topics: Electroconvulsive Therapy; GABA Antagonists; History, 20th Century; Hospitals, Psychiatric; Humans; | 2006 |
Seven years of experience with modified insulin treatment in neuroses and early psychoses.
Topics: Insulin; Mental Disorders; Neurotic Disorders; Pentylenetetrazole; Psychotic Disorders | 1949 |
Drug therapy with or without group discussion: effects of various regimens on the behavior of geriatric patients in a mental hospital.
Topics: Aged; Brain Diseases; Chlorprothixene; Estradiol; Female; Hospitals, Psychiatric; Humans; Male; Ment | 1967 |
Stimulants and other drugs for treatment of mental symptoms in the elderly.
Topics: Aged; Central Nervous System Stimulants; Cognition Disorders; Humans; Mental Disorders; Methylphenid | 1978 |
Central-nervous-system stimulants: appraisal of use in geropsychiatric patients.
Topics: Aged; Humans; Mental Disorders; Methylphenidate; Pentylenetetrazole | 1979 |
Combined electroconvulsive and drug therapy.
Topics: Anesthesia; Apnea; Atropine; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect | 1985 |
Improving psychiatric drug therapy. A matter of dosage and choice.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anticoagulants; Antidepressive Agents; Antiparkinson Agents; B | 1974 |
Succinylcholine in EST.
Topics: Diazepam; Electroconvulsive Therapy; Humans; Injections, Intravenous; Mental Disorders; Methohexital | 1973 |
A history of therapeutic fashions in psychiatry, 1800-1966.
Topics: Convulsive Therapy; Electroconvulsive Therapy; History, 19th Century; History, 20th Century; Hospita | 1967 |
[Comparison of the characteristics of the effect of tranquilizing agents under experimental and clinical conditions].
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Diseases; Chlordiazepoxide; Depre | 1971 |
[Statistical reports of the psychopharmacological agents used in the past 10 years in the Ospedale Neuropsichiatrico Provinciale of Mantua].
Topics: Chlorpromazine; Chlorprothixene; Humans; Mental Disorders; Orphenadrine; Pentylenetetrazole; Phenelz | 1967 |
[The psychiatric shock therapy from the viewpoint of experimental neuropathological studies].
Topics: Animals; Cats; Cerebellum; Cerebral Cortex; Convulsive Therapy; Electroconvulsive Therapy; Humans; I | 1969 |
Management of chronic mental patients.
Topics: Adult; Aged; Humans; Intracranial Arteriosclerosis; Male; Mental Disorders; Middle Aged; Nicotinic A | 1965 |
Medical aspects and emotional responses to geriatric behavior problems.
Topics: Aged; Dementia; Emotions; Female; Humans; Mental Disorders; Middle Aged; Pentylenetetrazole | 1966 |