pentylenetetrazole has been researched along with Atrophy in 3 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast, seizures between P20 and P30 did not result in cerebral atrophy or significant imaging abnormalities in the hippocampus or white matter, but irreversibly decreased PPI in the DG compared to normal adult controls." | 1.42 | Age-dependent long-term structural and functional effects of early-life seizures: evidence for a hippocampal critical period influencing plasticity in adulthood. ( Hutchinson, E; Meyerand, ME; Sayin, U; Sutula, T, 2015) |
| " Thus we aim to evaluate the effect of an increase in Cstb gene dosage on spontaneous epileptic activity and susceptibility to PTZ-induced seizure." | 1.37 | Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB. ( Bizot, JC; Brault, V; Costet, N; Hérault, Y; Martin, B, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sayin, U | 1 |
| Hutchinson, E | 1 |
| Meyerand, ME | 1 |
| Sutula, T | 1 |
| Brault, V | 1 |
| Martin, B | 1 |
| Costet, N | 1 |
| Bizot, JC | 1 |
| Hérault, Y | 1 |
| WAGNER, JW | 1 |
| DE GROOT, J | 1 |
3 other studies available for pentylenetetrazole and Atrophy
| Article | Year |
|---|---|
Age-dependent long-term structural and functional effects of early-life seizures: evidence for a hippocampal critical period influencing plasticity in adulthood.
Topics: Animals; Animals, Newborn; Atrophy; Corpus Callosum; Diffusion Tensor Imaging; Disease Models, Anima | 2015 |
Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB.
Topics: Animals; Atrophy; Brain; Cystatin B; Disease Models, Animal; Disease Susceptibility; Down Syndrome; | 2011 |
Changes in feeding behavior after intracerebral injections in the rat.
Topics: Acetylcholine; Animals; Appetite; Atrophy; Epinephrine; Feeding Behavior; Gallamine Triethiodide; Gl | 1963 |