pentylenetetrazole has been researched along with Astrocytoma in 2 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
Excerpt | Relevance | Reference |
---|---|---|
"India showed no abnormal seizure susceptibility or EEG response to photic stimulation and no electro-clinical features of epilepsy after pentylenetetrazol, 40 mg/kg sc." | 1.26 | Photic and pentylenetetrazol-induced seizure susceptibility in Macaca mulatta. ( David, J; Grewal, RS, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
FISCHER-WILLIAMS, M | 1 |
COOPER, RA | 1 |
David, J | 1 |
Grewal, RS | 1 |
2 other studies available for pentylenetetrazole and Astrocytoma
Article | Year |
---|---|
DEPTH RECORDING FROM THE HUMAN BRAIN IN EPILEPSY.
Topics: Adolescent; Amygdala; Astrocytoma; Bemegride; Caudate Nucleus; Child; Chlorpromazine; Electroencepha | 1963 |
Photic and pentylenetetrazol-induced seizure susceptibility in Macaca mulatta.
Topics: Animals; Astrocytoma; Brain Neoplasms; Craniocerebral Trauma; Electroencephalography; Haplorhini; Ma | 1977 |