Page last updated: 2024-11-08

pentylenetetrazole and Astrocytoma

pentylenetetrazole has been researched along with Astrocytoma in 2 studies

Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"India showed no abnormal seizure susceptibility or EEG response to photic stimulation and no electro-clinical features of epilepsy after pentylenetetrazol, 40 mg/kg sc."1.26Photic and pentylenetetrazol-induced seizure susceptibility in Macaca mulatta. ( David, J; Grewal, RS, 1977)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FISCHER-WILLIAMS, M1
COOPER, RA1
David, J1
Grewal, RS1

Other Studies

2 other studies available for pentylenetetrazole and Astrocytoma

ArticleYear
DEPTH RECORDING FROM THE HUMAN BRAIN IN EPILEPSY.
    Electroencephalography and clinical neurophysiology, 1963, Volume: 15

    Topics: Adolescent; Amygdala; Astrocytoma; Bemegride; Caudate Nucleus; Child; Chlorpromazine; Electroencepha

1963
Photic and pentylenetetrazol-induced seizure susceptibility in Macaca mulatta.
    Journal of medical primatology, 1977, Volume: 6, Issue:6

    Topics: Animals; Astrocytoma; Brain Neoplasms; Craniocerebral Trauma; Electroencephalography; Haplorhini; Ma

1977