pentylenetetrazole has been researched along with Ascorbic Acid Deficiency in 4 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures are a known co-occurring symptom of Alzheimer's disease, and they can accelerate cognitive and neuropathological dysfunction." | 5.42 | Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer's disease. ( Harrison, FE; Kang, JQ; Kennard, JA; Warner, TA, 2015) |
| "Seizures are a known co-occurring symptom of Alzheimer's disease, and they can accelerate cognitive and neuropathological dysfunction." | 1.42 | Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer's disease. ( Harrison, FE; Kang, JQ; Kennard, JA; Warner, TA, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Warner, TA | 1 |
| Kang, JQ | 1 |
| Kennard, JA | 1 |
| Harrison, FE | 1 |
| Odumosu, A | 3 |
| Wilson, CW | 3 |
4 other studies available for pentylenetetrazole and Ascorbic Acid Deficiency
| Article | Year |
|---|---|
Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; | 2015 |
Regional brain ascorbic acid distribution: its functional relationship to appetite and leptazol-induced convulsions in guinea-pigs.
Topics: Animals; Appetite Regulation; Ascorbic Acid; Ascorbic Acid Deficiency; Brain; Dose-Response Relation | 1980 |
The effect of vitamin C-deficienct diet and leptazol on the regional distribution of brain ascorbic acid in guinea-pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Brain; Female; Guinea Pigs; Male; Pentylenetetrazo | 1976 |
Proceedings: The relationship of ascorbic acid to leptazol-induced convulsions in guinea-pigs.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Guinea Pigs; Pentylenetetrazole; Seizures | 1974 |