pentylenetetrazole and Arrhythmias, Cardiac
pentylenetetrazole has been researched along with Arrhythmias, Cardiac in 20 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Cardiac arrhythmias are a proposed cause for some cases of SUDEP, yet the susceptibility and potential mechanism of arrhythmogenesis in Dravet syndrome remain unknown." | 1.39 | Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. ( Auerbach, DS; Clawson, BC; Isom, LL; Jones, J; Lenk, GM; Meisler, MH; Offord, J; Ogiwara, I; Parent, JM; Yamakawa, K, 2013) |
"Autonomic dysfunction, including arrhythmias, has been shown to be associated with epileptogenic activity." | 1.27 | The role of enkephalins in the production of epileptogenic activity and autonomic dysfunction: origin of arrhythmia and sudden death in the epileptic patient? ( Kraras, CM; Lathers, CM; Tumer, N, 1987) |
"Phenobarbital pretreatment depressed heart rate, blood pressure and postganglionic cardiac sympathetic neural discharge." | 1.27 | Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat. ( Carnel, SB; Lathers, CM; Schraeder, PL, 1985) |
Research
Studies (20)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (85.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (10.00) | 29.6817 |
2010's | 1 (5.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Auerbach, DS | 1 |
Jones, J | 1 |
Clawson, BC | 1 |
Offord, J | 1 |
Lenk, GM | 1 |
Ogiwara, I | 1 |
Yamakawa, K | 1 |
Meisler, MH | 1 |
Parent, JM | 1 |
Isom, LL | 1 |
Sahin, D | 1 |
Ilbay, G | 1 |
Imal, M | 1 |
Bozdogan, O | 1 |
Ates, N | 1 |
Taha, AY | 1 |
Ciobanu, FA | 1 |
Saxena, A | 1 |
McIntyre Burnham, W | 1 |
BIRCHER, RP | 4 |
KANAI, T | 1 |
WANG, SC | 4 |
FERRISS, GS | 1 |
HACKETT, ER | 1 |
TANG, RZ | 1 |
SHAO, BR | 1 |
XEI, RR | 1 |
CHAI, CY | 2 |
Suter, LE | 1 |
Lathers, CM | 7 |
Schraeder, PL | 5 |
Carnel, SB | 2 |
Weiner, FL | 1 |
Kraras, CM | 1 |
Tumer, N | 1 |
Bhargava, KP | 1 |
Ferrini, R | 1 |
Miragoli, G | 1 |
Croce, G | 1 |
Tymiński, W | 1 |
Czestochowska, E | 1 |
Szlabowicz, JW | 1 |
Makabe, T | 1 |
Rozear, M | 1 |
Tseng, DT | 1 |
Reviews
2 reviews available for pentylenetetrazole and Arrhythmias, Cardiac
Article | Year |
---|---|
Assessing the link between omega-3 fatty acids, cardiac arrest, and sudden unexpected death in epilepsy.
Topics: Animals; Anticonvulsants; Arrhythmias, Cardiac; Cardiotonic Agents; Convulsants; Death, Sudden, Card | 2009 |
Modulation of presynaptic gamma aminobutyric acid release by prostaglandin E2: explanation for epileptogenic activity and dysfunction in autonomic cardiac neural discharge leading to arrhythmias?
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Cats; Dinoprostone; Epilepsy; gamma-Aminobu | 1984 |
Other Studies
18 other studies available for pentylenetetrazole and Arrhythmias, Cardiac
Article | Year |
---|---|
Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cardiac Electrophysiology; Death, Sudden, Cardiac; | 2013 |
Vagus nerve stimulation suppresses generalized seizure activity and seizure-triggered postictal cardiac rhythm changes in rats.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Disease Models, Animal; Electrocardiography; Electroe | 2009 |
Mechanism of cardiac arrhythmias and blood pressure changes induced in dogs by pentylenetetrazol, picrotoxin, and deslanoside.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Deslanoside; Dogs; Lanatosides; Pentylenetetrazole; P | 1963 |
CARDIAC ARREST DURING INTRAVENOUS METRAZOL ADMINISTRATION. REPORT OF A CASE DURING EEG ACTIVATION PROCEDURE.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Electroencephalography; H | 1963 |
[SOME PHARMACOLOGICAL ACTIONS OF F30066].
Topics: Arrhythmias, Cardiac; Body Temperature; Central Nervous System; Gastrointestinal Tract; Guinea Pigs; | 1964 |
EFFECTS OF HEXAMETHONIUM AND TETRAETHYLAMMONIUM ON CARDIAC ARRHYTHMIAS PRODUCED BY PENTYLENETETRAZOL, PICROTOXIN AND DESLANOSIDE IN DOGS.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Central Nervous System; Deslanoside; Dogs; | 1965 |
Neural mechanisms in cardiac arrhythmias associated with epileptogenic activity: the effect of phenobarbital in the cat.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Disease Models, Anima | 1984 |
Cardiac neural discharge and epileptogenic activity in the cat: an animal model for unexplained death.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Death, Sudden; Electr | 1983 |
Autonomic dysfunction in epilepsy: characterization of autonomic cardiac neural discharge associated with pentylenetetrazol-induced epileptogenic activity.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Cats; Heart; Parasympathetic Nervo | 1982 |
Synchronization of cardiac autonomic neural discharge with epileptogenic activity: the lockstep phenomenon.
Topics: Animals; Arrhythmias, Cardiac; Cats; Dysautonomia, Familial; Electroencephalography; Epilepsy; Heart | 1987 |
The role of enkephalins in the production of epileptogenic activity and autonomic dysfunction: origin of arrhythmia and sudden death in the epileptic patient?
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Death, Sudden; Enkephalins; | 1987 |
Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electrocardio | 1985 |
On the importance of a central beta-adrenoceptor site in the antiarrhythmic activity of beta-blockers.
Topics: Aconitum; Adrenal Glands; Adrenergic beta-Antagonists; Alprenolol; Animals; Arrhythmias, Cardiac; Ca | 1972 |
Pharmacological actions of 1-(o-methoxyphenoxy)3-isopropylamino-2-propanol hydrochloride (S-D-1601), a new beta-blocking agent.
Topics: Adrenergic beta-Antagonists; Amphetamine; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antic | 1970 |
Activation of fibrinolysis during electroconvulsive treatment.
Topics: Anesthesia, General; Arrhythmias, Cardiac; Cold Temperature; Convulsive Therapy; Electric Countersho | 1971 |
[Influence of pentetrazol (PTZ), dimorpholamine (DMP) and trans-pi-oxocamphor (t-pi-oc) on the ventricular pacemaker of guinea pigs].
Topics: Amides; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Bradycardia; Camphor; Electrocardiog | 1969 |
Effects of intracerebroventricular l-hyoscyamine, ethybenztropine and procaine on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside.
Topics: Animals; Arrhythmias, Cardiac; Atropa belladonna; Bradycardia; Carotid Artery Thrombosis; Central Ne | 1968 |
Effects of synthetic oxytocin on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside.
Topics: Arrhythmias, Cardiac; Cardiovascular System; Electrocardiography; Heart Ventricles; Injections, Intr | 1968 |