pentylenetetrazole has been researched along with Arrhythmia in 20 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac arrhythmias are a proposed cause for some cases of SUDEP, yet the susceptibility and potential mechanism of arrhythmogenesis in Dravet syndrome remain unknown." | 1.39 | Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. ( Auerbach, DS; Clawson, BC; Isom, LL; Jones, J; Lenk, GM; Meisler, MH; Offord, J; Ogiwara, I; Parent, JM; Yamakawa, K, 2013) |
| "Autonomic dysfunction, including arrhythmias, has been shown to be associated with epileptogenic activity." | 1.27 | The role of enkephalins in the production of epileptogenic activity and autonomic dysfunction: origin of arrhythmia and sudden death in the epileptic patient? ( Kraras, CM; Lathers, CM; Tumer, N, 1987) |
| "Phenobarbital pretreatment depressed heart rate, blood pressure and postganglionic cardiac sympathetic neural discharge." | 1.27 | Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat. ( Carnel, SB; Lathers, CM; Schraeder, PL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (85.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Auerbach, DS | 1 |
| Jones, J | 1 |
| Clawson, BC | 1 |
| Offord, J | 1 |
| Lenk, GM | 1 |
| Ogiwara, I | 1 |
| Yamakawa, K | 1 |
| Meisler, MH | 1 |
| Parent, JM | 1 |
| Isom, LL | 1 |
| Sahin, D | 1 |
| Ilbay, G | 1 |
| Imal, M | 1 |
| Bozdogan, O | 1 |
| Ates, N | 1 |
| Taha, AY | 1 |
| Ciobanu, FA | 1 |
| Saxena, A | 1 |
| McIntyre Burnham, W | 1 |
| BIRCHER, RP | 4 |
| KANAI, T | 1 |
| WANG, SC | 4 |
| FERRISS, GS | 1 |
| HACKETT, ER | 1 |
| TANG, RZ | 1 |
| SHAO, BR | 1 |
| XEI, RR | 1 |
| CHAI, CY | 2 |
| Suter, LE | 1 |
| Lathers, CM | 7 |
| Schraeder, PL | 5 |
| Carnel, SB | 2 |
| Weiner, FL | 1 |
| Kraras, CM | 1 |
| Tumer, N | 1 |
| Bhargava, KP | 1 |
| Ferrini, R | 1 |
| Miragoli, G | 1 |
| Croce, G | 1 |
| Tymiński, W | 1 |
| Czestochowska, E | 1 |
| Szlabowicz, JW | 1 |
| Makabe, T | 1 |
| Rozear, M | 1 |
| Tseng, DT | 1 |
2 reviews available for pentylenetetrazole and Arrhythmia
| Article | Year |
|---|---|
Assessing the link between omega-3 fatty acids, cardiac arrest, and sudden unexpected death in epilepsy.
Topics: Animals; Anticonvulsants; Arrhythmias, Cardiac; Cardiotonic Agents; Convulsants; Death, Sudden, Card | 2009 |
Modulation of presynaptic gamma aminobutyric acid release by prostaglandin E2: explanation for epileptogenic activity and dysfunction in autonomic cardiac neural discharge leading to arrhythmias?
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Cats; Dinoprostone; Epilepsy; gamma-Aminobu | 1984 |
18 other studies available for pentylenetetrazole and Arrhythmia
| Article | Year |
|---|---|
Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cardiac Electrophysiology; Death, Sudden, Cardiac; | 2013 |
Vagus nerve stimulation suppresses generalized seizure activity and seizure-triggered postictal cardiac rhythm changes in rats.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Disease Models, Animal; Electrocardiography; Electroe | 2009 |
Mechanism of cardiac arrhythmias and blood pressure changes induced in dogs by pentylenetetrazol, picrotoxin, and deslanoside.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Deslanoside; Dogs; Lanatosides; Pentylenetetrazole; P | 1963 |
CARDIAC ARREST DURING INTRAVENOUS METRAZOL ADMINISTRATION. REPORT OF A CASE DURING EEG ACTIVATION PROCEDURE.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Electroencephalography; H | 1963 |
[SOME PHARMACOLOGICAL ACTIONS OF F30066].
Topics: Arrhythmias, Cardiac; Body Temperature; Central Nervous System; Gastrointestinal Tract; Guinea Pigs; | 1964 |
EFFECTS OF HEXAMETHONIUM AND TETRAETHYLAMMONIUM ON CARDIAC ARRHYTHMIAS PRODUCED BY PENTYLENETETRAZOL, PICROTOXIN AND DESLANOSIDE IN DOGS.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Central Nervous System; Deslanoside; Dogs; | 1965 |
Neural mechanisms in cardiac arrhythmias associated with epileptogenic activity: the effect of phenobarbital in the cat.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Disease Models, Anima | 1984 |
Cardiac neural discharge and epileptogenic activity in the cat: an animal model for unexplained death.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Death, Sudden; Electr | 1983 |
Autonomic dysfunction in epilepsy: characterization of autonomic cardiac neural discharge associated with pentylenetetrazol-induced epileptogenic activity.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Cats; Heart; Parasympathetic Nervo | 1982 |
Synchronization of cardiac autonomic neural discharge with epileptogenic activity: the lockstep phenomenon.
Topics: Animals; Arrhythmias, Cardiac; Cats; Dysautonomia, Familial; Electroencephalography; Epilepsy; Heart | 1987 |
The role of enkephalins in the production of epileptogenic activity and autonomic dysfunction: origin of arrhythmia and sudden death in the epileptic patient?
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Death, Sudden; Enkephalins; | 1987 |
Effect of phenobarbital pretreatment on cardiac neural discharge and pentylenetetrazol-induced epileptogenic activity in the cat.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electrocardio | 1985 |
On the importance of a central beta-adrenoceptor site in the antiarrhythmic activity of beta-blockers.
Topics: Aconitum; Adrenal Glands; Adrenergic beta-Antagonists; Alprenolol; Animals; Arrhythmias, Cardiac; Ca | 1972 |
Pharmacological actions of 1-(o-methoxyphenoxy)3-isopropylamino-2-propanol hydrochloride (S-D-1601), a new beta-blocking agent.
Topics: Adrenergic beta-Antagonists; Amphetamine; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antic | 1970 |
Activation of fibrinolysis during electroconvulsive treatment.
Topics: Anesthesia, General; Arrhythmias, Cardiac; Cold Temperature; Convulsive Therapy; Electric Countersho | 1971 |
[Influence of pentetrazol (PTZ), dimorpholamine (DMP) and trans-pi-oxocamphor (t-pi-oc) on the ventricular pacemaker of guinea pigs].
Topics: Amides; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Bradycardia; Camphor; Electrocardiog | 1969 |
Effects of intracerebroventricular l-hyoscyamine, ethybenztropine and procaine on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside.
Topics: Animals; Arrhythmias, Cardiac; Atropa belladonna; Bradycardia; Carotid Artery Thrombosis; Central Ne | 1968 |
Effects of synthetic oxytocin on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside.
Topics: Arrhythmias, Cardiac; Cardiovascular System; Electrocardiography; Heart Ventricles; Injections, Intr | 1968 |